http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8589168&dopt=Abstract
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Clin Infect Dis 1995 Nov;21(5):1322-4 |
The emergence of Haemophilus influenzae types
e and f as significant pathogens.
Waggoner-Fountain LA, Hendley JO, Cody EJ, Perriello VA, Donowitz LG.
Department of Pediatrics, University of Virginia Health Sciences Center,
Charlottesville 22908, USA.
Non-type b encapsulated Haemophilus influenzae meningitis (two cases due to H.
influenzae type e, two due to H. influenzae type f) was diagnosed in four
children in a 6-month period at the University of Virginia. H. influenzae type
b was the most common cause of bacterial meningitis in the United States before
the introduction of an effective vaccine, whereas the other five encapsulated
serotypes of H. influenzae rarely caused invasive disease. The clinical
features of non-type b H. influenzae meningitis and the therapy for this
infection are the same as those for type b H. influenzae disease. We report
these four cases to document an increase in infection due to non-type b
serotypes of H. influenzae, and we postulate that this change may result from
the well-documented decrease in H. influenzae type b oropharyngeal carriage and
disease that has occurred because of universal vaccination for H. influenzae
type b.
PMID: 8589168 [PubMed - indexed for MEDLINE]
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