LONDON (Reuters Health) May 02 - Scientists said on Thursday that
immunising children against varicella could increase the risk of
shingles in adults.
The team, at Britain's Public Health Laboratory Service, said that
although vaccination would save thousands of lives over time,
thousands of elderly people could also die from the complications of
herpes zoster.
Writing in the journal Vaccine, they called for a re-evaluation of
the policy of mass varicella vaccination that has been introduced
already in the United States and is imminent in many other countries.
In 1995, the varicella vaccine was approved for use in children older
than 1 year in the US and is now required for school entry.
Dr. Marc Brisson and his team report that adults living with
children have more exposure to the virus and enjoy high levels of
protection against shingles. Being close to children means that adults
are exposed to the varicella, which acts like a "booster" vaccine
against reactivation of the infection, they believe. But if all
children were vaccinated, adults who have had chickenpox would not
receive ongoing exposure, and would therefore be at greater risk of
developing shingles.
The researchers worked out a mathematical model that predicts that
eliminating chickenpox in a country the size of the United States
would prevent 186 million cases of the disease and 5,000 deaths over
50 years.
However they said it could also result in 21 million more cases of
shingles and 5000 deaths.
The PHLS said in a statement it was working out what the impact
might be of introducing a chickenpox vaccine in Britain.
"As more evidence becomes available, it will be shared with the
Joint Committee on Vaccination and Immunisation (JCVI) which advises
the Department of Health on the immunisation schedule."