Need for laboratory testing of congenital rubella syndrome

Guidelines for surveillance of congenital rubella syndrome and rubella - WHO

From the Introduction:  "Surveillance of congenital rubella syndrome (CRS) requires a comprehensive system to detect suspected CRS cases in infants who present to a range of different health services.  Suspected cases must be investigated, with full clinical and laboratory investigation."

Rubella Syndrome, Congenital - 1999 Case Definition - CDC

Case classification

Suspected: A case with some compatible clinical findings but not meeting the criteria for a probable case.

Probable: A case that is not laboratory confirmed and that has any two complications listed in paragraph "a" of the clinical case definition or one complication from paragraph "a" and one from paragraph "b", and lacks evidence of any other etiology.

Confirmed: A clinically consistent case that is laboratory confirmed.

Infection only: A case that demonstrates laboratory evidence of infection, but without any clinical symptoms or signs.

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