Reduced passive measles immunity in infants of mothers who have not been exposed to measles outbreaks.

  • warning: include_once(./sites/all/modules/date_backup/date/date.theme) [function.include-once]: failed to open stream: No such file or directory in /home/vaccgot7/public_html/includes/theme.inc on line 645.
  • warning: include_once() [function.include]: Failed opening './sites/all/modules/date_backup/date/date.theme' for inclusion (include_path='.:/usr/lib/php:/usr/local/lib/php') in /home/vaccgot7/public_html/includes/theme.inc on line 645.

Vaccination News Home Page

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10381212&dopt=Abstract

 
Scand J Infect Dis 1999;31(1):17-9 Related Articles, Books, LinkOut
Click here to read 
Reduced passive measles immunity in infants of mothers who have not been exposed to measles outbreaks.

Ohsaki M, Tsutsumi H, Takeuchi R, Kuniya Y, Chiba S.

Department of Pediatrics, Sapporo Medical University School of Medicine, Japan.

Natural measles infection usually confers life-long immunity which is transferred from mothers to their offspring, protecting them from natural measles until the age of about 12 months. Recently, however, natural measles has been observed with increased frequency in infants under the age of 12 months. Natural measles outbreaks in the city of Sapporo have been suppressed by widely applied measles vaccination. Passive measles immunity in 160 neonates (cord blood), born during the last 17 y in Sapporo, Japan was determined by a neutralization (NT) antibody test. The mothers of these infants had had natural measles infection during childhood. Geometric mean titres (GMTs) of cord blood NT antibodies gradually decreased after 1989 and the GMTs of the most recently born infants were significantly lower than those of infants born in the first few years of the study. These observations suggest that even in mothers who experienced natural measles in childhood, recurrent exposure to natural measles is necessary in order to maintain adequate antibody levels for effective passive immunity of their infants.

PMID: 10381212 [PubMed - indexed for MEDLINE]


AN: 99308942
 

Vaccination News Home Page

ALL INFORMATION, DATA, AND MATERIAL CONTAINED, PRESENTED, OR PROVIDED HERE IS FOR GENERAL INFORMATION PURPOSES ONLY AND IS NOT TO BE CONSTRUED AS REFLECTING THE KNOWLEDGE OR OPINIONS OF THE PUBLISHER, AND IS NOT TO BE CONSTRUED OR INTENDED AS PROVIDING MEDICAL OR LEGAL ADVICE.  THE DECISION WHETHER OR NOT TO VACCINATE IS AN IMPORTANT AND COMPLEX ISSUE AND SHOULD BE MADE BY YOU, AND YOU ALONE, IN CONSULTATION WITH YOUR HEALTH CARE PROVIDER.
 

Date: 
September 6, 2002