Reduced passive measles immunity in infants of mothers who have not been exposed to measles outbreaks.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10381212&dopt=Abstract

Scand J Infect Dis 1999;31(1):17-9

Reduced passive measles immunity in infants of mothers who have not been exposed to measles outbreaks.

Ohsaki M, Tsutsumi H, Takeuchi R, Kuniya Y, Chiba S.

Department of Pediatrics, Sapporo Medical University School of Medicine, Japan.

Natural measles infection usually confers life-long immunity which is transferred from mothers to their offspring, protecting them from natural measles until the age of about 12 months. Recently, however, natural measles has been observed with increased frequency in infants under the age of 12 months. Natural measles outbreaks in the city of Sapporo have been suppressed by widely applied measles vaccination. Passive measles immunity in 160 neonates (cord blood), born during the last 17 y in Sapporo, Japan was determined by a neutralization (NT) antibody test. The mothers of these infants had had natural measles infection during childhood. Geometric mean titres (GMTs) of cord blood NT antibodies gradually decreased after 1989 and the GMTs of the most recently born infants were significantly lower than those of infants born in the first few years of the study. These observations suggest that even in mothers who experienced natural measles in childhood, recurrent exposure to natural measles is necessary in order to maintain adequate antibody levels for effective passive immunity of their infants.

PMID: 10381212 [PubMed - indexed for MEDLINE]

AN: 99308942

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* ►February 8, 2010 - URGENT: Call Now, Stop NY Bill, Allows Kids To Decide All STD Vaccines Allowed Without Your Consent - The Autism Action Coalition

* ►February 8, 2010 - The Conflicting Views of Dr. Ben Goldacre and the Wakefield Affair - Ben Goldacre The conflicting views of Dr Ben Goldacre and the Wakefield affair: dumbing the public down. By John Stone - Age of Autism

* ►February 8, 2010 - Inovio Biomedical Cervical Cancer Therapeutic Vaccine Generates Dose-Related Immune Response in Clinical Trial - Inovio via BusinessWire via Technology Marketing Corporation - "VGX-3100 is a DNA vaccine targeting the E6 and E7 proteins of human papillomavirus (HPV) types 16 and 18 and is delivered via in vivo electroporation. Similar to previously reported data from the initial lowest dose cohort of this phase I trial, the vaccine was found to be generally safe and well tolerated. While previously reported data showed significant cellular and humoral immune responses, data from this second, intermediate dose group highlighted a significantly increased and dose-related immune response specific to the antigens targeted by the vaccine."..."While recent HPV preventive vaccines have been successful in protecting against infections that may lead to cervical cancer, Inovio's therapeutic vaccine targets the millions of women already infected with HPV and is intended to treat pre-cancerous cells and cervical cancer caused by this virus. Current vaccines do not serve this group of women," Dr. Kim added."

* ►February 6, 2010 - Autism Findings Retracted - The New American - "Actress Holly Robinson Peete remembers, 'When my son was two-and-a-half, he was just recovering from an ear infection and had been on antibiotics, therefore his immune system was suppressed. He had already missed several appointments for his vaccination so his pediatrician wanted to catch him up on all of them in the same day. Althrough I asked if he’d consider waiting or breaking up the cocktail, which contains three viruses, he laughed me out of the office and belittled me. I firmly believe that it took my son to a place of no return and his body could not handle it. He had a violent reaction with convulsions and then he stopped talking and slipped into a silence. He no longer said, 'Hi, Mommy,' he no longer responded to his name and he no longer made eye contact.”

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