Various Clinical Findings CRS

Rubella Syndrome, Congenital - 1999 Case Definition

Clinical case definition

An illness, usually manifesting in infancy, resulting from rubella infection in utero and characterized by signs or symptoms from the following categories:

a) Cataracts/congenital glaucoma, congenital heart disease (most commonly patent ductus arteriosus or peripheral pulmonary artery stenosis), hearing impairment, pigmentary retinopathy.

b) Purpura, hepatosplenomegaly, jaundice, microcephaly, developmental delay, meningoencephalitis, radiolucent bone disease.

Prominent Clinical Findings in Congenital Rubella Syndrome - "Vaccines", p. 410

Cataracts, retinitis, microphthalmia, glaucoma, cochlear deafness, central auditory imperception, patent ductus arteriosus, peripheral pulmonic artery stenosis, encephalitis, microcephaly, mental retardation, autism, intrauterine growth retardation, metaphyseal rarefactions, hepatosplenomegaly, thrombocytopenic purpura, interstitial pneumonitis, diabetes and hypothyroidism

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