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http://www.wfaa.com/wfaa/articledisplay/0,1002,20550,00.html

News 8 Investigates: Vaccine Safety Part 2
Reporter: Valeri Williams
Updated: Feb 23, 2001 at 12:57AM

DALLAS - Most parents trust the government to ensure that the vaccines we inject into our children are safe.

A News 8 Investigation focused on what some call the questionable science behind getting vaccines licensed in this country.

As we've said before and we want to stress again: traditional childhood vaccinations have been a good thing.

But what we've chosen to do with this is take a closer look at how some of the newer vaccines are coming on to the market, and to ask why parents aren't being told more.

"I feel like I took him to the doctor's office and I paid them to poison my son -- and I didn't know any better," said Melynda Slay.

In June 1999, Slay had her newborn son inoculated with the new RotaShield vaccine.

Vaccine ads from that time promised that RotoShield would help prevent childhood diarrhea. But within days, Harrison's bowels were dangerously obstructed to the point of possibly rupturing.

"That probably was the worst week I've ever had in my life because I wasn't sure if my son was going to live or die," Slay recalled.

Federal regulators from the Centers for Disease Control soon discovered that more than 100 other infants had suffered the same problem.

RotoShield was pulled off the U.S. market in less than 15 months and some are now questioning how the drug ever received government approval.

"These committees have become the rubber stamp committees for the drug companies to push their product in the market," said Dr. Erdem Cantekin, a medical researcher.

Cantekin has long been concerned about the financial links between the pharmaceutical industry and many doctors and scientists who sit on vaccine approval committees.

He is not alone.

Last summer Rep. Dan Burton (R-Ind.) held Congressional hearings which revealed that at least half the members of vaccine committees at both the Food and Drug Administration and the Centers for Disease Control had financial ties to drug companies developing different versions of the Rotavirus vaccine.

"We have had people who are head of advisory panels who own stock in pharmaceutical companies," Burton said.

The report found others who received grants or contracts worth hundreds of thousands of dollars, yet all were granted waivers which let them vote on the vaccine's approval.

"If you own stock in a pharmaceutical company, and you are on an advisory panel that will be approving or disapproving a vaccine by that pharmaceutical company and you know it could have an adverse impact on the stock that you hold in that company, it just might taint your judgment," Burton said.

On the very same day that the CDC's Vaccine Advisory Committee pulled the plug on RotoShield, it drafted a recommendation for another vaccine called Prevnar.

News 8's investigation found that out of 12 committee members, four had financial ties to the drug company making Prevnar.

At the FDA, three out of 12 committee members received waivers for conflicts of interest so they could vote on Prevnar's license.

Among them was Dr. Robert Daum, the newly-elected chairman of the committee.  He said his conflict amounted to research on another vaccine for children at another company.

"You have to understand I still drive my 1989 Toyota, and the door on the right side still doesn't open. Nothing good happened to me," Dr. Daum said.  "They're still selling God-knows how many million doses a year now for American Home Products. I don't benefit from that. Nothing has changed in my life."

Daum admitted, however, that his role is "a very fine line."

Daum and others argue that there is a very limited list of experts within the world of vaccine research. They say that in order to have the best professionals on the committees, there must be acceptance of conflicts of interest.

"No man can serve two masters," Cantekin countered. "I could find 100 competent scientists and doctors to put on these committees which are better than they have. All of whom don't have any conflict of interest and have not taken a single dollar from anybody."

He and others claim all this chumminess has made government committees unwilling to challenge poor testing procedures in studies of a proposed vaccine's safety.

For example, here are the results of a clinical trial of Prevnar in 38,000 California children:

According to the drug company's own documentation, children receiving Prevnar with other vaccines had more seizures, more rashes, higher fevers and other side effects than children who received the control vaccine.

And the real surprise? The control vaccine in the testing was not a placebo, but another experimental vaccine that was still being tested.

Dr. Daum defended the testing procedure. "I think it makes for better parent compliance and more willingness to participate to have a control that would actually benefit from receiving something, and not saline. I wouldn't want to submit my child to an experimental protocol where there was a chance he just going to get a dummy shot."

Barbara Fisher is the only member of the FDA's Vaccine Committee who is not a doctor or a scientist; she's a consumer advocate and the only committee member to have voted against issuing a license for Prevnar.

Fisher said the study leading up to the license fails to measure up -- ethically, morally or scientifically.

"What's scientific about that? That every time something bad happens after vaccination it's 'coincidence'? That's not science, that's politics," said Fisher.

Prevnar was licensed to vaccinate infants against certain strains of meningitis, pneumonia and bacteremia -- horrible diseases which combined affect fewer than 150,000 children each year.

Weighing the risks of vaccination versus the risks of disease is a tough decision for any parent, but what many parents have told us upsets them is that they were surprised -- and scared -- by how much information they did not know.

Rep. Burton said he is calling for another Congressional hearing on the approval of Prevnar this spring.

FOR MORE INFORMATION

 Prevnar: Official Web Site
 Prevnar Q & A
 House Committee Critical of Vaccine Approval Process
 Pediatrics Group Recommends Prevnar
 Parents Requesting Open Vaccine Education
 Texas Vaccine Schedule
 Vaccine Averse Event Reporting System
 CDC: Overview of Vaccine Safety
 More Information About Earaches
 The Centers for Disease Control and Prevention
 New Childhood Vaccine Targets Meningitis
 Report a Vaccine Reaction
 Eight Questions Parents Should Ask
 National Vaccine Information Center

 Note: These sites are not part of WFAA.COM website. WFAA.COM has no control
over their content or availability.

Copyright: 2001 by WFAA-TV Co. All Rights Reserved.


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Breaking News Archives - each day's breaking news from December 1, 2003 (check here for breaking news you might have missed and breaking news that didn't ever hit the "front page")

More News - all the news most recently posted on this website

All the News - a running tab of everything posted on this website since October 29, 2003

Top Stories Archives - daily breaking and other important news stories

Daily News Archives - all the news posted on this website each day (from April 2001)

Hot Topics - selected stories, by category

Return to Vaccination News Home Page (for best results, right click to "open in new window")

DISCLAIMER:    All information, data, and material contained, presented, or provided here is for general information purposes only and is not to be construed as reflecting the knowledge or opinions of the publisher, and is not to be construed or intended as providing medical or legal advice.  The decision whether or not to vaccinate is an important and complex issue and should be made by you, and you alone, in consultation with your health care provider.