Hot Topics - Vaccine-related issues - Adverse reactions/VAERS (includes non-vaccine-related)
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Vaccine-related issues - Adverse reactions/VAERS (includes non-vaccine-related)
March 1-7, 2004
►March 4, 2004 -
Group Seeks Ban of Anti-Cholesterol Drug - AP via Yahoo!
►March 4, 2004 -
4 subjects
challenge Lilly over drug trial - Outside overseer says he found no
indication that suicide victim was depressed - Indianapolis Star via
www.indystar.com - "Four participants in
an Eli Lilly and Co. drug trial in California said the clinic's staff told them
that Traci Johnson, who committed suicide last month during the same study in
Indianapolis, had a history of depression...But Dr. Rafat Abonour, chairman of
the institutional review board that reviews all Lilly drug trials at Indiana
University-Purdue University Indianapolis, said his review of Johnson's records
showed no such history."
►March 4, 2004 -
Addictive Effects
of Steroids Raise Questions About Users' Awareness (requires registration or
subscription) - The New York Times
►March 3, 2004 - Anti-depressants 'cause bleeding' - Elderly people and those with a history of bleeding disorders have been warned of the risk of taking certain types of anti-depressants. - BBC
February 23-29, 2004
►February 26, 2004 - Intranasal Influenza Vaccine Used in Switzerland During 2000-2001 Season Apparently Conferred a High Risk of Bell's Palsy - New England Journal of Medicine via Doctor's Guide - "The intranasal influenza vaccine used during the 2000-2001 influenza season in Switzerland was associated with a greatly increased risk of Bell's palsy that was highest during the second month after vaccination. This inactivated virosomal-subunit influenza vaccine, licensed only in Switzerland, is no longer in use...'In contrast, no significant risk of Bell's palsy was found to be associated with the parenteral influenza vaccines,' reports Margot Mutsch, PhD, MPH, World Health Organization Collaborating Centre for Travellers' Health, in Zurich, and colleagues."
Comment: The authors of this study are to be commended for following these vaccinees for more than a month.
►February 24, 2004 - New Health Dangers of Genetically Modified Food (and vaccines) Discovered - press release - Institute for Responsible Technology via Common Dreams Progressive Newswire - "Data from three groups of studies currently being conducted by the Norwegian Institute for Gene Ecology, in Tromsö, Norway, reveal potentially serious health dangers of genetically modified (GM) foods and vaccines...3. Genetically engineered pox viruses in cell cultures recombined with natural viruses to create new hybrid viruses with unpredictable and potentially dangerous characteristics."
►Canada's Adverse Drug Reaction database - CBC
►February 20, 2004 - What harm might antidepressants do? - The Globe and Mail
February 16-22, 2004
none selected this week
February 9-15, 2004
►February 14, 2004 - Vaccine risk acceptance depends on what you do and don't know - Georgia Institute of Technology Research News via www.eurekalert.org - "Beyond describing the factors that affect individual choices regarding vaccine risk acceptance, Bostrom also will discuss the sometimes-controversial public decision-making process on vaccination policy...'Controversy isn't always a bad thing,' she explains. 'Conflicts of interest can be real, and both scientific and policy processes should be scrutinized. Science, and in particular the science that has enabled vaccine development, has given us much longer, healthier lives. But engineering our immune systems is no mean task, and thinking broadly about that bigger picture is important.'Comment: Paul Offit is paid by the vaccine manufacturers to "explain" to doctors about the safety of vaccines.
January 26 - February 8, 2004 (2 weeks combined due to illness)
►February 7, 2004 - Increased susceptitibility to adverse effects from vaccinations (pdf) - by Teresa Binstock - submitted to the IOM Immunization Safety Review: Vaccines and Autism, to be held February 9, 2004
►February 2004 - Be prepared to recognize and treat anaphylaxis (requires registration) - Infectious Diseases in Children - "The risk of anaphylaxis following immunization is said to be about one in 1.5 per million (Pediatrics. 2003;112:815). As multiple vaccines often are given at the same visit, it is difficult to identify specific culprits...The Institute of Medicine has reported that causal relationships exist for the measles-mumps-rubella (MMR), hepatitis B and diphtheria-tetanus toxoids vaccines... It is difficult to estimate the risks of anaphylaxis to various agents, as episodes are not usually reported."
Comment: I'm not sure what they mean by "one in 1.5 per million". (Do they mean one to 1.5?) And per million what? Children? Doses? Chances are they mean doses, because that is traditionally how vaccine risk is assessed. But since children usually receive more than one dose, that skews estimates towards them being underestimated. For more on this, go to Scandals: Contemporary Legends - How To Lie With Statistics I
►Safety Data-Vaccine Excipient & Media Summary with Material Data Safety Sheet (MSDS) information and Vaccine Inserts. - Critical Decisions Count
►IOM Immunization Safety Review Committee Meetings - http://www4.nas.edu
January 19-25, 2004
none selected this week
January 12-18, 2004
►December 16, 2003 - Parents' vaccine concerns on the rise, making accurate information crucial - Concerns split between known short-term effects, and unproven or discredited theories - University of Michigan Health System via www.eurekalert.org
►
April 21, 2003 - Vaccination: A Grant of Immunity - www.cbc.ca - "What the BMJ calls 'a vocal minority of parents' in Britain are opposing vaccination, believing that the vaccination itself could be more dangerous than the disease. But, as the journal points out, diseases such as measles, diphtheria and polio are still common among unimmunized populations and could spread easily among a family or community that forgoes immunization."Comment: As seems to be the norm, the long-term consequences of vaccination are being compared to the mere incidence of disease. Except in those cases where there are long term consequences of disease, there may be little reason to avoid a disease, and some considerable reason to experience it. (For more on this, see, for instance, Scandals: Prescription For Disaster - Is Vaccine Policy A "House of Cards"?) Either the incidence of vaccination should be compared to the incidence of disease, in which case the incidence of vaccination might win out, but would, of course, be meaningless; or the long-term consequences of vaccination needs to be compared to the long-term consequences of disease. About that we know little since we have never compared the two in any meaningful way (see, for instance, comments re: No solid evidence links vaccines, autism).
January 5-11, 2004
►January 10, 2004 - Oculorespiratory Syndrome: Adverse Effect of Flu Vaccine - American Family Physician via http://i-medreview.subportal.com
►January 9, 2004 - Doubts on vaccine patch for children - Sydney Morning Herald - "An adhesive patch hailed as a revolutionary method of mass vaccination may increase a child's risk of developing type-one diabetes and multiple sclerosis, Australian researchers have found."
►January 7, 2004 - Vaccines: New Campaigns Against Scepticism, Says Sirchia - "'We must launch new vaccine campaigns, despite the recent scepticisms' said today health minister Girolamo Sirchia, in Genoa to attend the 'Children and the Mediterranean conference. 'The fact that a measles epidemic has killed three people in Campania and that flu kills thousands of people each year is a crime, just as ignoring that a vaccine exists is. There is an anti-scientific behaviour which establishes that the vaccine causes the disease. We have gone back to step 1, when Jenner and Pasteur were considered plague-spreaders'. According to the minister, the fear of vaccines is due to a lack of information: 'the more scientific development advances, the more anti-scientific movements come about. Today's vaccines are completely safe - concluded Sirchia - even the one against smallpox. There are no risks whatsoever'.
Comment: If it's not obvious by now that politics and medicine shouldn't mix, I don't know when it will be. "NO RISKS WHATSOEVER"? And why are these politicians (like Blair earlier today) suddenly speaking out, and so confidently and vociferously? What's up or about to be?
►January 3, 2004 - Vaccinate your child - National Post via www.canada.com - "As a general rule, parents know better than any one else how best to look after their children. That said, it seems more and more parents are making the wrong choice when it comes to vaccinating their offspring against potentially deadly diseases...Concerned than ever about the safety of vaccines, with many citing unfounded worries that the preventive shots are 'unnatural' and will cause everything from brain damage to multiple sclerosis."
Comment: Perhaps these fears are unfounded, but it is more likely they are not. For instance, a recent study, Risk factors of multiple sclerosis: a case-control study, found a highly significant relationship between measles vaccination and MS. And there has always been considerable evidence of brain damage, among the most noteworthy being the report co-authored by the "father of pediatric neurology", Dr. John Menkes, entitled Workshop on neurologic complications of pertussis and pertussis vaccination. Among the findings, it was reported that "Although the majority of seizures following pertussis vaccination are associated with fever, it was the consensus of the neurologists attending the workshop, that these do not represent febrile convulsions, but are non-benign convulsions (my emphasis)." The Institute of Medicine, in its safety review of vaccines, found, among other things, "that the evidence is consistent with a causal relation between DPT vaccine and acute encephalopathy and shock and 'unusual shock-like state'..." While it is unknown exactly how many actual vaccine-associated adverse reactions would be identified were they assiduously followed, cavalierly dismissing the over 100,000 of them, as if they must all be meaningless, is simply absurd. Some idea of their full extent and import can be gleaned from examination of VAERS reports, as long as estimates of under-reporting, ranging from 90-99%, are factored in. For instance, there were 269 reports of vaccine-associated encephalopathy, probably representing between 2,690 and 26,900 cases. There were another 371 reports (overlap unknown) of encephalitis, representing a possible additional 3,710 to 37,100 cases. If one takes into consideration the time between administration of vaccine and reports of infant death, and the extremely high percentage that appear to be occurring even within one day of vaccination, it should be clear that neither jubilation nor relief about the benign nature of vaccination is warranted. If reports of vaccine reactions are taken seriously, as they should be, it becomes apparent that the only thing that is truly unfounded is the notion that fears about vaccines are "unfounded".
►January 6, 2004 - Needle-free vaccines may cause more harm than good: study - AEDT via www.abc.net.au - "Professor Alan Baxter says the onset of auto immune diseases accelerated when the patches were tested on mice...This can lead to inflammation of the pancreas or brain."
►Diagnosis: Acute disseminated encephalomyelitis (presumptive) - Summary and Discussion - Baylor neurology case of the month - "Several infectious agents are thought to precede the development of ADEM, including: Measles (most common, 1/1000 measles cases, with autoreactive T-cells and antibodies to MBP), Rubella, Corona virus, Mycoplasma, influenza, parainfluenza, CMV, EBV, HHV-6, Varicella-chicken pox, and nonspecific URI's. Vaccines to smallpox, rabies (Semple vaccine), mumps, rubella, influenza and live measles have also been reported to antedate development of this condition."
December 29, 2003 - January 4, 2004
none selected this week
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