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Diseases and vaccines - Meningitis/meningitis vaccine/Prevnar/pneumonia/pneumococcal vaccine

March 1-7, 2004

►March 3, 2004 - U.S. Further Rations Meningitis Vaccine - Wall Street Journal via www.immunizationinfo.org (abstract)

►March 4, 2004 - Immunization controversy: Should colleges require the bacterial meningitis vaccine? - The Stanford Daily - "'I don’t think it would be a good policy to require the vaccine,' said Dr. Ira Friedman, who works at Vaden. 'A vaccine should be required only when its benefits far outweigh its costs, in dollars and otherwise. This is not the case for the meningococcal vaccine. That’s why public health authorities support an educational approach.'”...However, other medical professionals disagree with Friedman’s opinions and claim that there is no significant reason not to get the meningitis vaccine.  According to the CDC, the vaccine proves 85 to 90 percent effective against the most common strains,with rare side effects of mild redness or slight fever."

Comment:  For a different take on the vaccine, go to Scandals: Another Unnecessary Vaccine?  Here Comes the Hype for a New Meningitis Vaccine.

►March 2004 - Decrease of Invasive Pneumococcal Infections in Children Among 8 Children's Hospitals in the United States After the Introduction of the 7-Valent Pneumococcal Conjugate Vaccine - journal article (Pediatrics) - "Conclusions. Since the introduction of the PCV7, the number of invasive pneumococcal infections caused by vaccine-serogroup isolates among 8 US children’s hospitals has decreased >75% among children <=24 months old. In addition, penicillin resistance decreased in 2002 for the first time since our surveillance began in 1993–1994. However, we have noted that replacement may be developing with serogroups 15 and 33. Furthermore, penicillin resistance seems to be increasing among nonvaccine serogroups. Surveillance must be continued to detect the emergence of changes in the distribution of serotypes as well as antibiotic susceptibility."

Comment:  For more on this problem of serotype replacement, go to Scandals: Changing Disease Epidemiology Via Vaccines - Are We "Robbing Peter To Pay Paul"?.

►March 4, 2004 - LHS student dies of suspected meningitis - Lemoore Advance via www.newzcentral.com

Comment:  Although meningitis can be deadly, it is still a very rare event.  For that reason, vigilance is needed to guard against any hysteria generated over it.  For more on this, go to Scandals: Another Unnecessary Vaccine?  Here Comes the Hype for a New Meningitis Vaccine.

►March 2, 2004 - Senate Passes 2 New Bills On Vaccinations - Colleges Could Be Required To Give Info On Meningitis - www.theiowachannel.com

►March 2, 2004 - Pneumococcal Vaccine in Short Supply - Prevnar Shortage Prompts Change in Vaccination Recommendations - WebMD

►March 3, 2004 - A Shortage of Meningitis Vaccine (requires registration or subscription) - The New York Times - "Because of a severe shortage of a new vaccine to prevent meningitis and ear infections in young children, doctors should postpone giving the last two doses in a four-dose regimen, the Centers for Disease Control and Prevention recommended Tuesday...The shortage was caused by production problems at Wyeth Vaccines, the world's sole manufacturer of the vaccine, known as Prevnar, the disease centers said. The agency said the problems were not expected to be corrected until fall at the earliest...But Douglas Petkus, a spokesman for Wyeth, said he expected supply levels to return to normal by the summer, adding that the shortfall was a result of the company's efforts to keep up with the demand."

Comment:  Should the vaccine be used for ear infections?  Not if you believe "whistle blower" Dr. Erdem Cantekin.  (Also see, News 8 Investigates: Prevnar-Part 1 and News 8 Investigates: Vaccine Safety Part 2.)

►March 3, 2004 - Shortage of Meningitis Drug Continues (requires registration) - The Washington Post

►February 29, 2004 - New Vaccine Shortage - CDC via www.about.com

February 23-29, 2004

►March 1, 2004 - Meningococcal septicaemia: do not be reassured by normal investigations - journal article (Emergency Medicine Journal)

►February 28, 2004 - Fewer cases of meningitis reported - Fewer cases of meningococcal disease have been reported so far this year but health authorities still warn against complacency. - www.stuff.co.nz

►February 26, 2004 - Infant Vaccine Shortage Little Cause for Concern - The Intelligencer & Wheeling News Register

►February 26, 2004 - Pneumonia shots advocated - Capital Journal

February 23, 2004 - Children at risk as vaccine runs short - The Courier-Mail

►February 25, 2004 - New Report into Meningitis Diagnosis - www.itv.com

►February 24, 2004 - More babies needed for meningitis vaccine trial - Hundreds more babies are needed to take part in a pilot meningococcal vaccine programme in Auckland. - www.stuff.co.nz

February 16-22, 2004

►February 12, 2004 - Wyeth Reaffirms Distribution Plan for Prevnar(R) to Optimize Product Availability for Children - PR Newswire-First Call via Yahoo! Finance

►February 20, 2004 - The Meningitis Debate - More states are encouraging vaccines for students, despite objections from some campus health officials - The Chronicle Of Higher Education - "He learned that the disease is spread through saliva and can be transmitted through coughing, sneezing, shared drinks, or any other form of close contact. Most people who become infected, however, don't contract meningitis and aren't even aware that they are carriers. He also discovered that there is a vaccine that might have prevented him from catching the disease...On the surface, the meningitis laws are the swift product of grass-roots efforts to protect college students from a fatal disease. But many college health officials are questioning whether the laws are necessary. These officials argue that legislators have acted irrationally in response to lobbying efforts by pharmaceutical companies and emotional appeals from small groups of advocates."

►March 2004 - Nasopharyngeal Carriage of Streptococcus pneumoniae by Adults and Children in Community and Family Settings - journal article (Clinical Infectious Diseases)

►February 18, 2004 - Bill makes meningitis information mandatory - Colorado State Collegian - "A bill has been introduced to the Colorado General Assembly that would require all Colorado institutions of higher education to provide information about meningitis and the available vaccine to students living in campus housing...Students living in the residence halls have a slightly increased risk of contracting bacterial meningitis, an infection of fluid in the spinal cord and brain, according to a study by the Centers for Disease Control and Prevention completed in 2000...Up to 125 cases of bacterial meningitis occur on college campuses around the country, 10 to 15 of which have been deadly, said Lisa Duggan, immunization specialist at the Hartshorn Health Service...'It's not a huge number,' Duggan said. 'But it's tragic considering it is a preventable disease.'"

►February 18, 2004 - Dissemination of information on viral pneumonia accelerated nationwide - Vietnam News Agency

►February 19, 2004 - Babies at risk of pneumococcal - Herald Sun - "THOUSANDS of Victorian babies have been left exposed to the deadly pneumococcal disease as a global shortage of preventative jabs worsens...Vaccine-maker Wyeth said last month that babies who had begun the three-shot immunisation course would be able to finish the program...But worried parents have now been told supplies are no longer available, and they will have to wait at least four months before their children can resume the course...The delay will not negate the effect of the shots already administered, but those children do not have complete protection against the killer disease...Parents have been advised not to use an older pneumococcal vaccine."

►February 2004 - Culture-Negative Pericarditis Caused by Neisseria meningitidis Serogroup C - journal article (Journal of Clinical Microbiology) 

February 9-15, 2004

►February 12, 2004 - Health Groups Recommend Temporary Suspension Of Pediatric Pneumococcal Conjugate Vaccine Dose - press release - CDC

►February 13, 2004 - Shortage of Meningitis Vaccine May Delay Booster Shot for Some - Wall Street Journal via www.immunizationinfo.org (abstract)

►February 13, 2004 - Meningitis drugs blunder - Doctors are hoping to finish giving second doses of antibiotics to 80 children at Tiverton High School on Friday after it emerged a mistake had been made over the mixture. - BBC - "Pupils were given antibiotics on Tuesday after the death of a girl from meningitis the day before...But some of the children who were given the drug in liquid form received a dose that had not been properly mixed."

►February 13, 2004 - Health Officials Urge Halt to Meningitis Shots (requires registration) - Times Wire Services via The Los Angeles Times - "U.S. health officials urged doctors and nurses to temporarily suspend routine use of a booster shot that protects children against bacterial meningitis because of a looming shortage of vaccine...Curtailing the fourth dose of pneumococcal conjugate vaccine is not expected to hurt the health of children, officials said."

►February 12, 2004 - Health groups urge change in vaccination procedure - AP via www.nbc25.com - "Health care providers are being urged to suspend temporarily the routine use of a fourth dose of a widely used childhood vaccination...Three major health groups, including the Centers for Disease Control and Prevention, say the move would help conserve vaccine and minimize the likelihood of shortages caused by production and supply problems at Wyeth Vaccines. It's the only supplier in the U-S...The vaccine in question is pneumococcal conjugate (noo-moh-KAH'-kuhl KAHN'-joo-gut) vaccine, pr P-C-V-7. It can help prevent serious pneumococcal disease such as meningitis and blood infections. Health officials say cutting back to three doses from four won't have any adverse health consequences."

Comment:  If cutting back to three doses from four "won't have any adverse health consequences", what is the purpose of the fourth dose?  (That is, other than to line the coffers of the vaccine manufacturers?)

►February 12, 2004 - Homeless Vaccinated to Prevent Meningitis (requires registration) - The Los Angeles Times

►February 12, 2004 - Letter submitted to the Houston Chronicle re: A Mother's Message - She pushes for meningitis immunizations - as yet unpublished

Comment:  It will only be when the death and damage caused by vaccines and diseases both raise the same level of concern that vaccination policy can be viewed as having a moral and ethical base, and those who promote it as having honorable intent.  If vaccination policy continues to be supported and administered based on the notion that some unknown, but presumed to be small, number must be sacrificed for someone's notion of the "common good", it will remain a bankrupt, immoral policy.  This well-written letter by the mother of a vaccine-damaged child represents the fair-minded, honorable view that current vaccination policy lacks.

►February 11, 2004 - Viral pneumonia reported from 27 provinces and cities - Vietnam News Agency

►January 2004 - Are economic evaluations of vaccines useful to decision-makers? Case study of Haemophilus influenzae type b vaccines. - journal article (Pediatric Infectious Disease Journal)

►January 2004 - Outbreak of Haemophilus influenzae type b disease among fully vaccinated children in a day-care center. - journal article (Pediatric Infectious Disease Journal) - "Conclusions. Although immunization against Hib has resulted in a reduction in the incidence of this disease in the UK, individual protection cannot be assumed to be infallible. The importance of timely chemoprophylaxis of close contacts of a child with invasive Hib disease is reinforced."

►February 2004 - Case-control studies of the effectiveness of vaccines: validity and assessment of potential bias - journal article (Pediatric Infectious Disease Journal) - "Because case-control studies of the effectiveness of vaccines are nonexperimental, it is difficult to assure that bias does not affect the validity of the results...Conclusion. With the use of a virtually identical study design, vaccines against Hib were shown to be highly effective in preventing invasive Hib infections but were not effective in preventing invasive infections due to S. pneumoniae. Case-control studies are a valid method of assessing the effectiveness of vaccines."

►February 11, 2004 - Prevention of viral pneumonia enhanced - Vietnam News Agency - "According to the Health Ministry, the country had by Feb. 11 had 197 viral pneumonia patients in 27 provinces and cities, 18 of whom contracted the strain of H5N1 virus. Thirty-five died, including 14 H5N1 virus carriers."

January 26 - February 8, 2004 (2 weeks combined due to illness)

►February 2004 - Impact of pneumococcal and influenza vaccines on otitis media - journal article (Current Opinion in Pediatrics) 

2004 -Vaccine sparks fall in meningitis deaths - The Evening Times, UK

February 4, 2004 - A Mother's Message: She pushes for meningitis immunizations - Houston Chronicle - ""I just want to scream when I run into these people who say immunization doesn't work or it works only part of the time or it has risks," she said one recent afternoon in the dining room of her home southeast of Conroe...Inoculation against the disease is not required in Texas, but the U.S. Centers for Disease Control and Prevention recommends vaccination when an area experiences more than 10 cases per 100,000 population within 90 days...Bacterial meningitis remains comparatively rare, with Texas registering 119 cases in 2002. But Milley believes that number is low because mild cases are sometimes treated as some other illness and go unreported."

Comment:  For more on meningitis vaccine and meningitis risk, go to Scandals: Another Unnecessary Vaccine?  Here Comes the Hype for a New Meningitis Vaccine.

January 19-25, 2004

►January 21, 2004 - Bacterial Meningitis risk appears small - Officials get word out after death - Tri-Valley Herald Online - "'It's important to emphasize that it really requires ongoing, close intimate contact with somebody that has been diagnosed with meningococcal meningitis to put you at risk for exposure,' said Dr. Peter Dietrich, medical director of Berkeley's University Health Service. 'So casual exposures like eating in the same dining hall together or attending a class together, or going to the training room or the weight room or passing each other on the campus is not the type of exposure we're worried about.'"

►January 23, 2004 - Vaccine close to release - International pharmaceutical company Chiron Corporation is speeding up the manufacture of the new vaccine designed to combat the deadly meningoccocal B epidemic hitting New Zealand. - www.stuff.co.nz

►January 20, 2004 - Doctors try to trace disease that killed Cal basketball player - Contra Costa Times via www.sanluisobispo.com - "The disease that killed University of California Berkeley basketball player Alisa Lewis on Monday probably is not a risk to those who had contact with her, but university health officials who don't know where or how she was exposed, aren't taking any chances...About five percent of the general population carries the bacterium without showing symptoms and will never get sick, said infectious diseases expert Dr. Arthur Reingold, chairman of epidemiology at University of California Berkeley's School of Public Health. But the carriers can spread it to others, usually by sneezing, coughing, kissing, or sharing cups and eating utensils...Both doctors said the public has little to fear. "This bacterium can't last outside the body longer than two minutes," Reingold said. "It doesn't get spread by casual contact...'Only a tiny fraction of those who are exposed ever get sick," he said. "Most of us are have antibodies that protect us. But if you're that rare individual who doesn't have those antibodies, as this young lady apparently didn't, you're definitely at risk.'"

January 12-18, 2004

►January 17, 2004 - Meningitis deaths unrelated, officials say - AP via www.thestate.com - "A high school student who died Jan. 9 was thought to have meningitis, but tests came back negative. Officials think the tests may have been affected by antibiotics given before a spinal tap was done."

Comment:  How often do things like this happen?

January 16, 2004 - Life-saving baby jabs running low - The Herald Sun - "THOUSANDS of newborn Australian children will miss out on shots against the deadly pneumococcal disease as a global vaccine shortage takes effect...Australian supplies of the Prevenar vaccine will not be fully restored until at least April, according to manufacturer Wyeth...The drug company has been forced to halt production of Prevenar at its US plant amid an upgrade to meet increased international demand."

January 5-11, 2004

►January 9, 2004 - Tragic mum's plea for rare bug vaccine - The Mercury - "The first time Stacey Harper heard of pneumococcal disease was a few minutes after her seven-year-old son died...Jacob, her only child, lost his life to streptococcus pneumonia septicemia less than six hours after arriving in hospital."

January 10, 2004 - Query on bug vaccine - The Mercury - "The Health Department is investigating whether a meningococcal C vaccine may have failed after a child contracted the illness...Last month there were four suspected cases of meningococcal C...Three of the cases were from one family and the children had received the meningococcal C vaccine. ..Further testing found only one child contracted the illness, while the other two received precautionary treatment."

 

Comment:  Given the fact that there are no short or long-term, properly designed studies comparing the vaccinated to the never vaccinated (or those vaccinated, but not against meningitis), it is impossible to know how well the vaccine works.  For more on the new meningitis vaccine, and possible ramifications of its use, go to Scandals: Another Unnecessary Vaccine?  Here Comes the Hype for a New Meningitis Vaccine (originally published under another title).

 

►January 7, 2004 - Scandals: Another Unnecessary Vaccine?  Here Comes the Hype for a New Meningitis Vaccine was Scandals: Is the excitement about a new meningitis vaccine warranted or is it premature?

 

►January 6, 2004 - Meningitis experts pin hopes on new vaccine - Plans for immunisation of children against B strain - Belfast Telegraph - "Meningitis experts in Northern Ireland said today they were "crossing their fingers" that a new vaccine would be the breakthrough needed to protect against the most dangerous form of the illness...The Meningitis Research Foundation was commenting on latest research carried out by scientists at the University of Surrey which could allow doctors to immunise children against meningitis B for the first time."

 

►January 6, 2004 - Vaccine ' could beat meningitis' - Scientists believe they may have found a way to protect people against every strain of meningitis. - BBC

 

►January 6, 2004 - Scientists: Meningitis Vaccine Breakthrough - The Scotsman, UK

►January 5, 2004 - Hope For New Meningitis Vaccine - University of Surrey via www.innovations-report.com - "The Surrey researchers used genetic engineering technology to make a mutant group of the meningococcus that was incapable of causing disease in mice. The mutant was made in a C group of the meningococcus. However, mice that were inoculated with the mutant group developed antibodies that killed not only C groups but also B and A groups. It appears that, by inoculating with the disabled group, the mice have effectively been immunised against all groups."

Comment:  But what about the problem of changing serotypes, with them sometimes becoming more virulent, due to outside pressure like vaccines and antibiotics?

►December 30, 2003 - Meningitis Cases Have Unrelated Strains - AP via www.intelihealth.com

December 29, 2003 - January 4, 2004

►December 30, 2003 - Meningitis Drops in 2003, Despite Several Recent Cases - Boston Globe via www.immunizationinfo.org (abstract) - "New Hampshire health officials have disclosed that the strain of meningitis that killed an 18-year-old woman in the Bennington area is not the same strain that infected two 15-year-old students in Keene, allaying fears that an outbreak of the dangerous illness is erupting. In addition, two other youths who contracted meningitis last week appear to have no relation to any of the other cases. In fact, the rate of meningitis infection has dropped in 2003 despite this recent jump in the disease's visibility."

January 4, 2004 - Meningitis group urges child vaccinations - www.2theadvocate.com - "The chances of dying from bacterial meningitis, which has claimed the lives of two area teen-agers in the past month, are about one in a million in Louisiana, health officials said...But such odds, as small as they seem, are still too great for the National Meningitis Foundation."

Comment:  If there were no potential risks from meningitis vaccine, perhaps this would be a no-brainer.  But there are. (There have been 644 adverse meningitis vaccine-associated reactions, representing in all likelihood between 6,440 and 64,400 cases, reported to VAERS so far.)

►December 29, 2003 - Docs Hunt Teen Meningitis Link - "If all of the strains of the bacteria match, and certainly if there are more cases, that would be more concerning." Jesse Greenblatt, state epidemiologist - AP via CBS News

December 30, 2003 - Meningitis Cases Have Unrelated Strains - AP via The Herald-Sun

December 29, 2003 - Meningitis victim was sent home by hospital - N.H. teen lacked 'classic' symptoms - The Boston Globe - "Greenblatt said the 15-year-olds appear to have spread the disease to one another, but health officials had found no links between the other cases. Ells, Gilman, and Perry all contracted a strain of the disease that cannot be prevented by vaccination. Health officials were testing to determine whether the Colebrook boy had the same strain, and suspect the Concord-area boy did, as well....'If all of the strains of the bacteria match, and certainly if there are more cases, that would be more concerning," Greenblatt said. "It would mean that there is potentially more risk from a new strain that has entered the area.'"

Additional comment: Given the propensity for serotypes to change, and the possibility that vaccination can drive such changes, perhaps there is marginal benefit in exposing people to any possible risks of meningitis vaccine.  (There have been 644 adverse meningitis vaccine-associated reactions, representing in all likelihood between 6,440 and 64,400 cases, reported to VAERS so far.)  For more on the this problem, go to Scandals: Changing Disease Epidemiology Via Vaccines - Are We "Robbing Peter To Pay Paul"?

 

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DISCLAIMER:    All information, data, and material contained, presented, or provided here is for general information purposes only and is not to be construed as reflecting the knowledge or opinions of the publisher, and is not to be construed or intended as providing medical or legal advice.  The decision whether or not to vaccinate is an important and complex issue and should be made by you, and you alone, in consultation with your health care provider.