Hot Topics - Diseases and vaccines - Flu/flu vaccine
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Diseases and vaccines - Flu/flu vaccine
March 1-7, 2004
►March 6, 2004 - Flu alarm rang falsely, state says - Portland Press Herald - "As Maine's flu season winds down, it appears that predictions of an abnormally severe outbreak were overblown. The flu season in Maine was "not particularly noteworthy," state epidemiologist Kathleen Gensheimer said, despite reports from Western states that this year's flu strain was breaking out early and hitting hard...'There's a fine line between providing information and scaring people,' Gensheimer said. 'This story was sensationalized all the way up the channels.'"
►March 2, 2004 - New, Deadly Flu Pandemic 'Inevitable,' Experts Warn - USA Today via www.immunizationinfo.org (abstract)
Comment: How do they know it is "inevitable"? Do we really know why the 1918 flu pandemic occurred and that it is a repeatable event? If so, how do we "know" that?
►March 4, 2004 - Bills seek to allow greater access to flu shots - Legislation would expand pharmacists' powers to give vaccinations - Baltimore Sun
►March 4, 2004 -
Texas working quickly to solve avian flu issue - Country World News
►March 4, 2004 -
Japan
calls in army to contain bird flu -
www.abc.net.au
►The Immunization of Children against Influenza can Protect the Elderly - media release - Leeds, Grenville & Lanark District Health Unit
►March 3, 2004 -
Inactivated Flu Vaccine Works in Kids Too -
Clinical Infectious Diseases via Reuters via Yahoo!
►March 3, 2004 - Health Hype -
What Ever
Happened to the Flu Scare? - ABC News - "The flu is now at levels well below
last season ...Health officials had acknowledged that the vaccine formula this
season did not cover the so-called 'Fujian' strain of virus, but encouraged
vaccinations just the same."
►March 3, 2004 -
Moment of
truth nears on bird flu - Asia Times
►March 2, 2004 -
Vietnam's National Assembly Standing Committee told bird flu contained -
Xinhuanet via China View
►March 2, 2004 -
Officials see big threat from avian influenza - USA Today via The Desert Sun
►March 2, 2004 -
Avian
Influenza - A 'moving target' for diagnosticians - Ag News, Texas A&M
University Agriculture Program
►March 2, 2004 -
U.S.
flu season is over - UPI via The Washington Times
►March 2, 2004 -
Targeted
Antiviral Prophylaxis Of Flu Case Contacts Could Successfully Contain Pandemic
Influenza - Emory University Health Sciences Center via Science Daily - "In
a future outbreak of pandemic influenza, such as the three pandemics that
sickened millions and killed hundreds of thousands of people during the 20th
century, supplies of flu vaccine might not be available quickly enough to
contain the spread of disease. However, according to research by
biostatisticians in Emory University's Rollins School of Public Health, many
thousands of deaths could be prevented if antiviral agents were given to the
close contacts of those with suspected cases of flu until adequate supplies of
vaccine could be manufactured and distributed."
►March 2, 2004 -
MedImmune Looks to Boost FluMist Sales - Company Hopes New Version Will Fix
Problems Faced by Nasal Vaccine in Its Debut (requires registration) - The
Washington Post
►March 3, 2004 - USDA Says Bird Flu in Texas Appears Contained - Reuters via Yahoo! News
►March 3, 2004 -
`Flu' an informative, precise look at the 1918 pandemic -
http://metromix.chicagotribune.com
- "In recent American history, the experience with flu is mostly one of minor
inconvenience and, perhaps, major discomfort...But epidemiologists, insurance
companies and an increasing number of citizens understand that the influenza
virus, in one form or another, has the potential to do much worse in the
not-too-distant future...In 1918, influenza
caused the worst pandemic in the world's history, more lethal than the Black
Death, killing more people in months than World War I had in four years."
►March 1, 2004 -
Unexpected lessons learned this flu season - New influenza strain reminds
the public that influenza is not harmless while making health officials aware of
the vaccine program's shortcomings. (requires registration) - The Los Angeles
Times - "As it turns out, the 2003-04 flu season appears to have been no worse
than many other seasons. Even though it peaked extremely early — in December —
the numbers of people who became sick or died weren't unusual...The
season did have an impact, however. As health officials prepare for a new
season, they're paying special attention to the last season's legacy — both in
public awareness and in their strategies to deal with new outbreaks."
►March 2, 2004 - Flu Season Seems Over, Officials Say (requires registration or subscription) - The New York Times - "The flu season appears to have ended early and as abruptly as it started, and was not much more severe than usual seasonal outbreaks, federal health officials said here on Monday...'The influenza season has wound down very dramatically, declining to levels lower than we often expect at this time of year,' said Dr. Keiji Fukuda, a top influenza expert at the Centers for Disease Control and Prevention."
Comment: So much for the benefits of creating hysteria (unless you consider vaccine manufacturer profits a benefit of vaccination). For more on this, go to How the Mass Media in the U.S. Created Flu Hysteria and Helped Drive the Vaccine Markets for the Makers of FluMist And Fluzone. - by RFD columnist Sherri Tenpenny, DO in the Online Vaccines Conference @ www.redflagsdaily.com
►March 2, 2004 -
Flu threatens
world, experts say - Pandemic risk at 30-year high, scientists report - The
Atlanta Journal-Constitution
►March 1, 2004 -
CDC
warns of pandemic dangers posed by avian flu - USA Today - "The flu season
is fading away, but experts warn that a far greater menace may be on the
horizon: The avian flu galloping across Asia poses "the most serious pandemic
threat since 1968," Keiji Fukuda said Monday at the International Conference on
Emerging Infectious Diseases...A pandemic caused by a flu strain that is new,
deadly to humans and highly contagious "is inevitable," he said, but no one
knows when it may strike."
Comment: From the people who just brought you the 2003-2004 flu season hysteria and who apparently believe you just can't have too much hysteria (warranted or not).
►March 1, 2004 - Troubled
FluMist Vaccine to Remain in Production - Status of Saatchi on $40 Million
Account Still Unknown - www.adage.com - "MedImmune
today said it will continue producing troubled nasal flu vaccine FluMist,
despite slumping sales and the possibility of a $75 million write-off if Wyeth
bows out of a co-marketing agreement on the drug."
►March 1, 2004 -
FluMist Flop Dogs MedImmune -
www.thestreet.com - "Medimmune
said Monday that it would stick with FluMist, its inhaled flu vaccine, conceding
that the product wouldn't produce meaningful financial results until the
2007-2008 flu season. FluMist has been a flop, but the company insisted that an
improved version of the drug launched in September could eventually produce
annual U.S. sales of $500 million."
►March 2, 2004 -
Bird-flu shot ready for trials - The Standard - "A vaccine for
the deadly H5N1 virus is ready for testing on humans and is expected to be
available in six months, the World Health Organisation (WHO) said
yesterday...The United Nations health agency had said in January that a vaccine
may not be available until next winter...The new vaccine was developed by using
a technology that involves genetic modification of the virus."
Comment: It may sound great on the surface, but what are the risks? For instance, it was recently reported that genetic modification of vaccines may may pose considerable problems: "Genetically engineered pox viruses in cell cultures recombined with natural viruses to create new hybrid viruses with unpredictable and potentially dangerous characteristics". Dr. Bonnie Dunbar, a vaccine researcher, testified that the recombinant hepatitis B vaccine causes serious side effects.
►March 1, 2004 - MedImmune Plans to Keep FluMist Alive - MedImmune to Keep FluMist Alive Despite Dismal Sales, Lowering Outlook for the Coming Year - AP via ABC News
►March 1, 2004 - Unexpected
Lessons Learned This Flu Season - Los Angeles Times via
www.immunizationinfo.org
(abstract)
►February 29, 2004 -
Experts say Flu to Cost Asia $500 Million (requires registration) - The Los
Angeles Times
►February 29, 2004 - Great Influenza killed quickly, cruelly, perversely - Vivid history of U.S. epidemic of 1918 is also a cautionary tale for our times (requires registration) - book review - The Providence Journal
February 23-29, 2004
►February 28, 2004 - Farm's reticence shocks officials - No Notification Despite Mass Fowl Deaths - The Japan Times - "Health and animal experts expressed shock at the news Friday that a chicken farm in Tanba, Kyoto Prefecture, did not notify officials that thousands of its birds had died despite mounting bird flu fears...The incident highlights the difficulties involved in trying to contain an infectious disease when announcing that a farm is affected is virtually certain to cripple its business."
►February 29, 2004 - Flu Vaccinations (requires registration or subscription) - letter - The New York Times - "I was upset to learn that such a low percentage of health care workers are immunized...It baffles me that health care officials would make such a big deal about the public's taking part in immunization when the people hired to help the public get healthy and stay healthy aren't even participating."
Comment: This college student is right to be baffled.
►February 29, 2004 -
Thailand reports one more suspected human bird flu infection - Xinhuanet via
China View
►February 29, 2004 -
Farm shipped
15,000 live chickens despite seeing mass deaths - Japan Today
►February 20, 2004 - Bird Flu in Pennsylvania Poses Uncertain Risk to People - Gene Analysis Is Underway for New Strain - Genome News Network
►February 15, 2004 - Avian influenza ("bird flu") and the significance of its transmission to humans - WHO
►February 23, 2004 - Egg Beaters - Flu vaccine makers look beyond the chicken egg - Scientific American
►February 23, 2004 - Flu vaccine makers look beyond the chicken egg - Scientific American
►February 26, 2004 - Experts say bird flu virus may be eliminated in a year, vaccine available soon - www.channelnewsasia.com
►February 28, 2004 - Va. worker may have caught avian flu - Fell ill as it swept the Shenandoah Valley's poultry farms in 2002 - Richmond Times-Dispatch
►February 28, 2004 -
Asia Faces Huge Cost in Bird Flu Fight - Reuters via Yahoo!
►February 27, 2004 -
Racing ban looms as equine flu resurfaces - Saturday Weekend Argus via
www.iol.co.za
►February 21, 2004 -
Bird Flu
Politics Hits Poor Hardest - The Nation/ANN via
http://e.sinchew-i.com
►February 23, 2004 - Is it safe? - Clarksburg Exponent Telegram - "The state Department of Health and Human Resources distributed 68,000 flu vaccine doses this flu season, with 63,000 of them containing a chemical the U.S. Food and Drug Administration has suggested be removed from childhood vaccines..Joe Thornton, state Health and Human Resources spokesman, said 5,000 were pediatric doses that did not contain thimerosal, a preservative containing mercury."
►February 26, 2004 -
Most
of nasal spray flu vaccine unsold - UPI via The Washington Times - "Eighty
percent of the new nasal spray vaccine FluMist, manufactured by MedImmune Inc.,
of Gaithersburg, Md., went unsold in the United States...MedImmune told a
federal panel Tuesday in Atlanta about 4 million doses of leftover FluMist would
most likely have to be destroyed."
►February 26, 2004 -
Nasal Flu Vaccine Available for Free - The Ledger
►February 26, 2004 -
Scientific Tests
Led to Bird Flu Upgrade - Sophisticated Tests Led Scientists to Upgrade Bird
Flu Risk - AP via ABC News
►February 26, 2004 -
Conditions 'ripe' for human bird flu - AP via The Australian
►February 26, 2004 - Human bird flu
vaccine nearly ready - Could be widely available in 3-6 months, scientists
say - Reuters via MSNBC
►February 27, 2004 -
UN conference hears bird flu crisis poses "unprecedented" threat - AFP via
www.channelnewsasia.com - "'Never
in the past have we witnessed an avian virus circulating so quickly in such a
large part of the world,' he said in a statement as experts from 23 Asia Pacific
nations convened for three days of talks...Vallat said the immediate priority
for affected nations was to stop the virus in its tracks by slaughtering
infected poultry as well as birds that had come in contact with them."
►February 26, 2004 -
Health Asia - Better Detection Key to Avoiding New Bird Flu Crisis - If Asia
is to avoid another avian flu crisis, the region has to change the current ways
that its poultry industry has been expanding and put into place new surveillance
systems to detect animal diseases, experts said here Thursday. - Inter Press
Service News Agency
►February 26, 2004 -
Intranasal Influenza Vaccine Used in Switzerland During 2000-2001 Season
Apparently Conferred a High Risk of Bell's Palsy -
New England Journal of Medicine via
Doctor's Guide - "The intranasal influenza vaccine used during the 2000-2001
influenza season in Switzerland was associated with a greatly increased risk of
Bell's palsy that was highest during the second month after vaccination. This
inactivated virosomal-subunit influenza vaccine, licensed only in Switzerland,
is no longer in use...'In contrast, no significant risk of Bell's palsy was
found to be associated with the parenteral influenza vaccines,' reports Margot
Mutsch, PhD, MPH, World Health Organization Collaborating Centre for Travellers'
Health, in Zurich, and colleagues."
Comment: The authors of this study are to be commended for following these vaccinees for more than a month.
►February 26, 2004 - Superflu is being brewed in the lab - New Scientist - "After the worldwide alarm triggered by 2003's SARS outbreak, it might seem reckless to set about creating a potentially far more devastating virus in the lab. But that is what is being attempted by some researchers, who argue that the dangers of doing nothing are even greater...We already know that the H5N1 bird flu virus ravaging poultry farms in Asia can be lethal on the rare occasions when it infects people. Now a team is tinkering with its genes to see if it can turn into a strain capable of spreading from human to human. If they manage this, they will have created a virus that could kill tens of millions if it got out of the lab."
►February 22, 2004 - China capable of detecting bird flu in human beings - Xinhuanet via China View
►February 22, 2004 -
In Oregon: New
flu-like virus strikes in Medford - Statesman Journal
►February 22, 2004 -
Flu fighters mix
science, soothsaying - Decisions made now will affect next vaccine (requires
registration) - The Kansas City Star
►February 22, 2004 -
New
DNA-based test speeds diagnosis of avian influenza - In a matter of hours,
it can determine both the presence and strain of the disease. - Philadelphia
Inquirer via www.philly.com
►February 25, 2004 -
Researchers to gauge bird flu's lethal potential - AP via The Seattle Times
►February 25, 2004 -
Bird Flu Spread Among Humans Would Be Deadly - Human Cases Mount, but Still
No Giant Leap to Mankind - www.webmd.com
►February 25, 2004 -
Leading Health and
Labor Organizations Call For Improved Influenza Vaccination Rates Among Health
Care Workers - National Foundation for Infectious Diseases Joins Supporters
to Issue Call to Action for Institutions to Increase Dismally Low Immunization
Rates Among Health Care Workers - press release - National Foundation for
Infectious Diseases via PRNewswire via Yahoo!
►February 25, 2004 -
Tough Times for Nasal Flu Vaccines - HealthDay via Palm Beach Post
►February 25, 2004 -
U.S. public health chief says emergence of SARS, avian flu the "new normal"
- Canadian Press via www.canada.com - "The
flurry of exotic infectious diseases that have threatened global health in the
past couple of years aren't an aberration - they are the new reality, the
director of the U.S. Centers for Disease Control said Wednesday...The rapid-fire
emergence of diseases like SARS, West Nile virus, monkeypox and avian influenza
point to a future where new and serious health threats arise on a regular basis
from nature, Dr. Julie Gerberding said in an interview from nearby Hamilton,
where she was speaking at McMaster University."
►February 26, 2004 - Study Finds Most Health Care Workers Do Not Get Flu Vaccines (requires registration or subscription) - The New York Times - "Only 36 percent of health workers receive influenza vaccinations each year, despite a longstanding federal recommendation that such workers be immunized for their own protection and to prevent the spread of the disease, a leading health organization said here Wednesday."
►February 22, 2004 - Deadly human diseases often arrive via animals - Global travel, conditions in food processing, exotic pets cited in new strains - The News Journal via The Detroit News - "The danger of these diseases to become pandemics often has been exaggerated, some scientists said. Even so, scientists and health officials cannot ignore the possible danger."
►February 23, 2004 -
U.S. Watches Texas Farmworkers for Bird Flu Symptoms - Reuters
►February 24, 2004 -
Scientists Test
Potential of Bird Flu - AP Exclusive: Scientists Experiment With Bird Flu
Virus to Test How Dangerous It Could Be - AP via ABC News
►February 24, 2004 - Flu vaccines reduce death rates by 40% - European Respiratory Journal via Medical News Today
Comment: Unless they compared
people who were vaccinated against the flu vaccine to those who have not been
vaccinated against the flu, including those who have never been vaccinated at
all, they simply do not know what is going on.
►February 23, 2004 -
Low
Pathogenic Avian Influenza in British Columbia - Canadian Food Inspection
Agency via Canada News Wire
►February 25, 2004 - Spray Flu Vaccine Is Little Used, Even With Shots Scarce (requires registration or subscription) - The New York Times
►February 24, 2004 -
Universal flu shots considered - USA Today
►February 25, 2004 -
Flu Vaccines for Everyone? If Uncle Sam made shots universal, a stabilized
vaccine industry might be ready for the killer virus doctors have long feared -
Business Week
►February 22, 2004 -
When death was all around: the flu of 1918 - History Offers Insight into
Microbes to Come - Washington Post via The Mercury News
►February 24, 2004 - Flu shots for all could become goal - Cox News Service via Longview News-Journal - "This is long overdue,' said Dr. Paul Offit, chief of infectious diseases at Children's Hospital of Philadelphia, who served on ACIP until last summer. 'Influenza is an infectious disease than can be prevented easily and safely, and it should be.'"
Comment: First, it is important to bear in mind that Paul Offit is highly conflicted, counting among his various financial ties to the vaccine industry, being paid by them to tout their safety to doctors. Second, while the claim is made that it can be prevented easily and safely, in truth, no one knows whether the benefits of flu vaccine outweighs its risks. The benefits are assumed, and the risks either dismissed or ignored. Let's see some long-term studies comparing the flu vaccinated to the never vaccinated and then we'll have some idea whether or not the benefits outweigh their risks.
►February 24, 2004 - CDC Study: Flu Shot Effective Up to 63 Percent for Adults 50-64 - AP via www.immunizationinfo.org (abstract)
►March 1, 2004 - Flu testing is usually not cost-effective - Studies suggest physician judgment may be a sounder means of diagnosing and treating influenza. - American Medical News via www.ama-assn.org
►February 23, 2004 - CDC being advised on flu shots for all - Experts mull yearly plan for vaccinations - Atlanta Journal-Constitution - "Vaccination experts who advise the Centers for Disease Control and Prevention are debating a significant change in immunization policy: Suggesting or recommending that every American receive a flu shot every year...If the change becomes policy, it could - depending on the strength of its wording - more than triple the number of flu shots now given annually in the United States."
Comment: What's the chance this has something to do with the flu vaccine manufacturer's demanding that the government create more demand for their vaccine? (See Flu Vaccine Makers Say Gov't Must Increase Demand.)
►February 24, 2004 - Fatal Bird Flu Diagnosed in Texas Flock (requires registration) - Reuters via The Washington Post
►February 22, 2004 - Report on avian-flu source expected - CanWest News Service via www.canada.com
►February 23, 2004 - Australian drug could combat avian flu - ABC Rural via www.abc.net.au
►February 22, 2004 - Bird Flu Comes to Texas - www.kfdx.com
February 16-22, 2004
►February 21, 2004 - Maryland Orders Poultry Farms to Test Chickens for Avian Flu before Processing - The Baltimore Sun via www.miami.com
►February 22, 2004 -
Bird
flu in China comes under gradual control: official - Xinhuanet via China
View
►February 22, 2004 -
Asia
urged to step up bird flu fight - One News via
www.nzoom.com
►February 21, 2004 -
Eastern US Poultry Industry Worries About Avian Influenza Outbreak - Voice
of America
►February 22, 2004 -
The next big
threat: killer influenza - The Times of India
►February 22, 2004 -
Bird flu in cats poses no risk for humans: WHO - Daily Times
►February 22, 2004 -
Killer flu: Could the world cope? - It is only a matter of time before a
major outbreak of potentially deadly flu, according to scientists. Could the
world cope? - BBC
►February 20, 2004 - FluMist failure makes MedImmune rethink the vaccine business - Maryland Gazette - "The research chief of MedImmune told a House committee last week that the company may get out of the flu vaccine-production business, following disappointing sales of its nasal-spray vaccine this flu season...The Gaithersburg company, one of only three in the nation that manufacture flu vaccines, plans to destroy nearly 4 million of its 5 million doses of FluMist, said James Young, president of research and development for MedImmune. Young said it took the company 30 years and $1 billion in research and development to produce the spray...'It's hard to justify staying in the business, if we are hemorrhaging left to right,' Young said...He noted that the company even tried giving away up to 1 million doses to local jurisdictions, but there were no takers."
Comment: I wonder if they did pre-development market research to see if there was demand for a product like this?
►February 21, 2004 - Mild Avian Flu Strain on Texas Chicken Farm Believed Not Harmful to Humans - The Washington Times via www.miami.com
►February 21, 2004 - Canadians ill after bird flu alert - Herald Sun - "FIVE people on a farm in British Columbia on Canada's west coast, where bird flu was discovered this week, had fallen ill with flu-like symptoms, government officials said today...But they stressed the public should not worry because the strain of avian influenza - confirmed to be a low pathogenic H7 strain - was mostly harmless to humans, unlike the H5 strain that has killed 22 people and forced the slaughter of millions of chickens in Asia...'These are five individuals who had intensive exposure to sick chickens. This is not a virus with a propensity to spread from human to human,' said David Patrick, of the British Columbia Centre for Disease Control."
►February 20, 2004 - FDA Adds Potent Strain to New Flu Vaccine (requires registration) The Los Angeles Times
►February 19, 2004 - Inactive Flu Vaccine May be Safe for Kids - UPI via Comtex via www.wtopnews.com
►February 20, 2004 - Birdflu vaccine seen top priority to stop pandemic - Reuters AlertNet
Comment: But what if concerns
raised in
New Scientist are true, that vaccinations may be what is at least partly
responsible for the current flu problem?
►February 19, 2004 -
Yamaguchi bird flu virus capable of infecting humans: Japanese institute -
The bird flu virus that killed chickens in Japan's Yamaguchi Prefecture is
capable of infecting humans, but its virulence is weak, the Japanese National
Institute of Animal Health said Thursday - People's Daily
►February 20, 2004 - Bird Flu Found in Cats in Asia; Canada on Alert - Reuters - "Two domestic cats in Thailand have died of the same bird flu that has killed at least 22 people in Asia, a veterinarian said on Friday, a day after Canada announced its first case of a different strain of the virus...The discoveries have alarmed scientists who now fear the disease can spread as easily between species as it has between countries."
►February 19, 2004 - Protein helps immune system mount ’instant strike’ against deadly flu viruses - Discovery suggests that a ’live virus’ vaccine may offer best defense against avian flu - University of Rochester Medical Center via Innovations Report
►February 19, 2004 - Avian influenza strains vary, but all pose potential risk to human health - Canadian Press via www.canada.com - "The discovery of avian influenza in a B.C. chicken flock is no reason to push the panic button, but it does require quick action to protect poultry stocks and human health, experts say...The H7 strain found at the farm on B.C.'s Lower Mainland is 'leaps and bounds different from H5N1, where there's high lethality, not only in chickens but also in humans,' influenza expert Dr. Danuta Skowronski of the British Columbia Centre for Disease Control said Thursday. The H5N1 strain has swept through Asia..."But what we want to do - always, whenever there's an avian outbreak - is contain it and minimize human exposure.''
►February 20, 2004 -
Bird flu kills house cats, raising fears infected pets could pass it to owners
- Canadian Press via www.canada.com
►February 20, 2004 -
Are pigs
carrying flu superbug? - The Avian flu that has claimed 22 lives in the Far
East has now been found in pigs. Because the animals are vulnerable to both bird
and human flu, scientists fear the virus could mutate inside them into a
superstrain like the one that killed up to a fifth of the world's population in
1918 - Times Online, UK
►February 20, 2004 -
Drug effective against avian flu - A drug used to treat flu has been shown
to be effective against the avian strain of the disease sweeping Asia. - BBC
►February 20, 2004 -
Mild Strain of Bird Flu Found in Texas - Reuters
►February 20, 2004 -
WHO Sees No New Threat from Bird Flu in Cats - Reuters - "Confirmation
that bird flu has jumped the species barrier and killed two cats in Thailand
should not signify any increased danger to humans from the killer disease, the
World Health Organization (WHO) said on Friday...Furthermore, there was no
reason that this would help trigger a feared mutation in the virus making it
more of a threat to people, it added.►February 18, 2004 - This
winter's flu season turns out to be moderately severe despite early vaccinations
- AP via Alaska Journal of Commerce
►February 18, 2004 - Meanwhile: Echoes of panic over global disease - International Herald Tribune - "These 1838 remarks might cause us to ask whether in the age of SARS and bird flu alarms it is not time to subject the statements of certain virologists, headline writers and health bureaucracies to critical analysis by those trained in other disciplines."
Comment: Interesting article.
►February 18, 2004 - Report finds inactivated influenza virus vaccines effective in children - Infectious Diseases Society of America via www.eurekalert.org - "Every winter inevitably brings with it the flu season, but kids don't inevitably have to contract the flu, according to an article in the March 1 issue of Clinical Infectious Diseases, now available online. The report, which reviews the results of multiple studies on the effects of influenza vaccine on children, indicates that 'killed' influenza vaccine is a safe and effective method to reduce the rate of influenza in children as young as 6 months old."
Comment: This is the study listed yesterday which was paid for by Aventis Pasteur, an influenza vaccine producer.
►February 19, 2004 - Imperfect flu vaccine leaves expert uncertain (requires registration) - Minneapolis - St. Paul Star Tribune - "This winter's flu season turned out to be only moderately severe despite an early start and a vaccine that didn't include the strain that caused most illness, according to government data presented Wednesday...Preliminary results of a CDC study of 50- to 64-year-olds in Colorado found those at particularly high risk from influenza got little if any protection. But a study of the families of 114 Air Force personnel who caught the flu suggests the vaccine was 40 percent effective."
►February 18, 2004 -
U.S. Experts Struggle with Flu Vaccine Questions - Reuters Health
via Yahoo! - "Various studies show the vaccine had effectiveness ranging from
none at all to 60 percent -- statistics that confounded experts trying to decide
how best to protect the public from the highly contagious virus...'It's hard to
make sense of it,' Dr. Bruce Gellin, director of the Health and Human Service
Department's National Vaccine Program Office, told reporters...'We really need
to have a system in place year to year that tracks the efficacy of the
vaccine.'"
►February 19, 2004 -
Government isn't sure how good the flu vaccine was - AP via
www.kesq.com
►February 18, 2004 -
Officials Hope Next Flu Vaccine Works Better - Flu Vaccine to Change -- but
No Bird Flu Protection Yet - WebMD - "Even in a good year -- when the flu
vaccine is a perfect match with the flu virus that actually circulates -- the
vaccine is not 100% effective. In such years, the flu vaccine offers 70% to 90%
protection. Healthy adults get the best protection, while the elderly and
children vaccinated for the first time usually get somewhat less protection."
►February 2004 - Predicting the supply and implementation strategies needed to immunize children and adolescents against influenza - journal article (Journal of Pediatrics) - "Between 5 and 10 million individuals aged 6 months to 17 years have conditions (predominantly asthma) that indicate influenza vaccination."
Comment: This recommendation is particularly
interesting in light of recent findings that there is No
asthma exacerbation help from children's flu vaccination.
►February 2004 -
Prevalence and characteristics of children at increased risk for complications
from influenza, United States, 2000 - journal article
(Journal of Pediatrics) - "Results
Approximately 5.2 to 10.0 million children aged 6 months through 17 years
(7.4%-14.2%) had high-risk conditions indicated for influenza vaccination.
Asthma accounted for the majority of conditions."
►March 2004 - Inactivated Influenza Virus Vaccines in Children - journal article (Clinical Infectious Diseases) - "In conclusion, the data show that killed influenza vaccines in children are safe, immunogenic, effective, and potentially cost-saving."
Comment: Note that this is an Aventis Pasteur study. Among their many products are vaccines, including one for influenza.
►February 18, 2004 - Bird flu: don't eat chicken if there's an outbreak - Utusan Malaysia Online
►February 18, 2004 - Japan declares end to its first bird flu case - Reuters AlertNet
►February 18, 2004 - Asia's toll from bird flu rises to 22 - AP via The Globe and Mail
►January 28, 2004 - Official blasts study showing flu shot falls short - Influenza vaccine is at least partially effective, Health Canada doctor says (requires registration) - The Medical Posting
►February 17, 2004 - WHO
optimistic on flu - Avian bug not 'major concern' for humans - AFP via
International Herald Tribune
►February 17, 2004 -
UN: Eradication of Bird Flu Virus May Be Impossible - Reuters - "The
United Nations food agency's director of animal health said Tuesday it may be
impossible to eradicate the spiraling bird flu virus that has ravaged the Asian
poultry sector and killed 20 people...Samuel Jutzi, director of the U.N. Food
and Agriculture Organization's (FAO) animal health department, said some 80
million birds had been culled or died from the disease and that experts were
still not sure of the source of the epidemic."
►February 17, 2004 -
Delaware Finds No New Bird Flu Cases - Reuters
►February 18, 2004 -
Latching On to a Horror - Scientists fear a pandemic if the deadly avian flu
virus, which hooks into victims' cells, mutates and spreads between humans.
(requires registration) - The Los Angeles Times
►February 18, 2004 -
Flu Vaccine to Change Next Year (requires registration or subscription) -
The New York Times - "Next season's vaccines for the United States are expected
to include the Fujian strain that has caused most of this season's flu cases
here and in Europe. The Fujian strain will replace the strain known as
A/Moscow...Next season's vaccine will also substitute the B/Shanghai strain for
the B/Hong Kong strain. The new vaccine will still include the A/New Caledonia
strain."
►February 12, 2004 - WHO Confirms No Human-to-Human Bird Flu Infection - Reuters via www.immunizationinfo.org (abstract)
►February 17, 2004 - Hygiene hypothesis questioned - Previous exposure to influenza A virus increases predisposition to asthma - The Scientist
►February 18, 2004 - No asthma exacerbation help from children's flu vaccination - Today in Vidyya
►February 16, 2004 - A flu jab for all toddlers? - The Scotsman
►February 16, 2004 - State to determine whether avian flu outbreak involved live virus (requires registration) - AP via www.pennlive.com
►February 16, 2004 -
Parents pay up for jabs - Evening Mail via icBirmingham.co.uk
►February 16, 2004 -
What are
dangers of the bird flu? (registration required) - United Features Syndicate
via The Post and Courier
►February 16, 2004 -
Highly Pathogenic Avian Influenza in Thailand -This is a Follow-up report
(No. 1) via OIE on the recent outbreak of Avian Influenza in Thailand. - Poultry
News via www.thepoultrysite.com
►February 16, 2004 -
Highly Pathogenic Avian Influenza in the US - This is a report via OIE on
the recent outbreak of Avian Influenza in America. - Poultry News via
www.thepoultrysite.com
►February 16, 2004 -
A hint of the flu - The Globe and Mail - "Health experts fear that somewhere
in the world today -- perhaps in Asia, where avian flu has killed at least 19
people -- a particularly dangerous genetic change may be taking place in a known
influenza virus and creating something new, like the SARS virus, to which humans
have no immunity. If such a virus were able to spread easily from person to
person, a pandemic could occur similar to the one in 1918-19, when Spanish flu
killed an estimated 50 million people around the world...Flu viruses undergo
such antigenic changes frequently (though thankfully with less dire
consequences).
►February 15, 2004 - Bird-Brained Flu Hype - New York Post - "AVIAN flu, if it morphs into a human-to- human virus, could cause another worldwide epidemic like the one in 1918, when almost a billion people got sick, 50 million died and the Great War ground to a halt. This is the public health message that has been broadcast over the media megaphone recently...The U.S. public, tired of influenza from December's over-hyped outbreak, and not that concerned about health care in other countries to begin with, isn't buying this message. But because the public is sure to buy some later message about some other hyped bacteria or virus, we must look at how public health officials choose to inform - or misinform - us."
►February 14, 2004 - Mortality from avian flu is higher than in previous outbreak - journal article (BMJ) - "The mortality in Vietnam of between 60% and 70% is much higher than the 30% mortality of the 1997 outbreak in Hong Kong, said Professor David Hui, a respiratory medicine specialist at the Chinese University of Hong Kong. Professor Hui is in Vietnam as part of a team of specialists who are training medical staff in infection control and treatment of H5N1 avian flu...."This is a puzzle... we are trying to find out: is the virus changing in structure? Is it becoming more virulent? Is the clinical spectrum different from 1997?' Professor Hui told Reuters Television."
►February 12, 2004 - A Review of This Year's Flu Season - Does Our Public Health System Need a Shot in the Arm? - House Committee on Government Reform
►February 15, 2004 -
State confirms avian flu in Lancaster County flock - The state Agriculture
Department confirmed an outbreak of avian flu at a Lancaster County farm, but
said the strain infecting the flock is not likely to be harmful to humans. - AP
via Nepa News
►February 15, 2004 -
China Finds More Bird Flu Ahead of Crisis Talks - Radio Free Asia
►February 16, 2004 -
Ban on farm hit by avian flu may be lifted - The Japan Times
►February 16, 2004 -
Bird Flu
Outbreak Has Farmers Jittery (requires registration or subscription) - The
New York Times - "The influenza strain, known as H7, is not a danger to humans,
and is not even particularly deadly for chickens. But if allowed to spread,
health experts say, it can mutate into a more virulent strain for animals.
Consequently, the state typically orders entire flocks destroyed when even a
single bird becomes infected."
►February 16, 2004 - Flu
illness 'may bring on asthma' - Catching flu early in life may actually
increase the chances of a child developing asthma later, say experts. - BBC -
"Their finding, in a study of mice, contradicts the suggestion that early
infections have a protective effect...Writing in the journal Nature Immunology,
the team from Stanford University say that flu boosted the body's allergic
responses."
February 9-15, 2004
►February 14, 2004 - US agriculture leaders hit out Asian countries banning American poultry imports - Channel News Asia►February 14, 2004 - Thailand's PM confident bird flu is beaten - www.abc.net.au
►February 15, 2004 -
Concern as bird flu makes the jump to other species - Taipei Times
►February 14, 2004 -
China's bird
flu claim suspect - The Atlanta Journal-Constitution
►February 14, 2004 - Flu jabs scandal puts old at risk - icBirmingham.co.uk - "Half a million elderly people in the Midlands are at risk of catching killer flu because of a vaccination flop...The prediction comes after it was revealed that less than HALF the primary care trusts in the region had hit Government targets for offering the life-saving jabs."
Comment: Is the government ignorant of the fact that this year's flu vaccine probably doesn't work, or do they just don't care?
►February 13, 2004 - Bird flu strain in Pennsylvania said no threat to humans - Reuters via Forbes
►February 13, 2004 - New Flu Vaccine Provides Insight into Immunity Development, Says Stanford Researcher - Stanford University Medical Center via Business Wire
Comment: Wouldn't it be better to understand immunity prior to using vaccines, rather than use them under the assumption that they both work and are safe?
►February 14, 2004 - Bird flu eradication 'may take years' - AFP via The Australian►February 12, 2004 - Chiron
to Testify to Congress on Influenza Vaccine - President and CEO Howard Pien
to Appear at U.S. House of Representatives Government Reform Committee Hearing
Today - PRNewswire-FirstCall via
http://interestalert.com - "'"Chiron is committed to meeting demand for flu
vaccine in the United States, today and tomorrow,' said Mr. Pien...'Strengthening
our public health infrastructure -- to increase immunization rates in the
inter-pandemic years -- is the single most important initiative today to prepare
for tomorrow's pandemic.'"
►February 12, 2004 - Flu
bugs more dangerous than terrorists, county officials told - Billings
Gazette
►February 13, 2004 - Bird Flu Vaccine Is Called Feasible - Boston Globe via www.immunizationinfo.org (abstract)
►February 10, 2004 - Indonesia Importing Bird Flu Vaccine From China, Despite Concerns About Its Quality - AP via www.intelihealth.com
►February 13, 2004 -
Bird
flu viruses have geographic features - Xinhuanet via China View
►February 13, 2004 -
Bird flu victim's father sues Thai government - Financial Times - "The angry
father of a six-year-old Thai boy who died of bird flu has filed a legal
complaint against the Thai government, accusing it of covering up the lethal
disease, with fatal consequences for his son...Chamnan Bounmanut, whose son
Captan was the first of five Thais to die from the H5N1 bird flu virus, says the
boy would be alive today if the government had issued public warnings that bird
flu was sweeping through Thai poultry and could infect people."
►February 13, 2004 - Bird flu confirmed in Shanghai - China has confirmed seven new outbreaks of bird flu in four regions including one on the financial centre, Shanghai, previously just a suspected case. - BBC
►February 13, 2004 - Planning for a nightmare - Health Canada outlines strategy in case of a flu pandemic - Experts prepare for staggering hardships and losses - The Toronto Star►February 13, 2004 -
Officials Say Avian Flu Poses No Threat in New Jersey (requires registration
or subscription) - The New York Times
►February 13, 2004 -
New
Zealand not to ban cold and flu medicine - Xinhuanet via China View - "The
New Zealand government has decided not to ban common cold or flu medicines on
pharmacy shelves in the country, New Zealand Press Association reported
Friday...Pseudoephedrine, a major ingredient in many medicines, not onlysoothes
cough and cold but also is used in the manufacture of the illegal drug
methamphetamine (speed), which was reclassified as a Class A drug last year."
►February 13, 2004 -
WHO bird flu study finds virus infects humans fast, kills quickly - AFP via
www.channelnewsasia.com - "The
first study of Asia's bird flu cases shows the virus has an alarmingly high
fatality rate and that victims typically die less than two weeks after falling
ill with raging fever and breathing difficulties...The World Health Organisation
(WHO) survey of 10 human cases of bird flu in Vietnam, where 14 people have died
of the disease, found that of the group eight died, one recovered and another
remains in a critical condition."
►February 13, 2004 -
FAO:
bird flu not under control yet - Xinhuanet via China View
►February 13, 2004 -
Leopard Dies of Bird Flu - A leopard has died from bird flu in a Thai zoo,
it was disclosed today. - The Scotsman - "An
official at the zoo said the leopard’s death 'may have been as a result of it
eating chicken infected with bird flu'...The World Health Organisation said it
had little information about the case – but if confirmed it could be the first
time the disease has jumped to exotic animals or members of the cat family."
►February 13, 2004 -
Vietnam rejects WHO criticism over handling of bird flu outbreak - AFP via
www.channelnewsasia.com
►February 12, 2004 - Avian flu found at four New Jersey live chicken markets; officials say no danger to humans - AP via The Hannibal Courier-Post
►February 13, 2004 - Bird flu short incubation: study - AP via The Australian
►February 13, 2004 -
WHO assurance on bird flu scare - The World Health Organisation (WHO) has
dispelled fears of bird flu being transmitted by humans in Vietnam. -
Aljazeera.net
►February 12, 2004 -
MedImmune thinking twice about staying in vaccine business - CNS via
www.sunherald.com - "The
research chief of Gaithersburg-based MedImmune told a House committee Thursday
that the company may get out of the vaccine-production business, following
disappointing sales of its nasal-spray vaccine this flu season."
Comment: "BL Fisher Note (from the NVIC newsletter): When America's free enterprise system is allowed to work properly, without government coercion, then those products the public needs and wants will be purchased and consumed and those the public does not need or want will not be purchased and consumed. That leaves the way open for other manufacturers to build a better mousetrap and persuade the public to use that better mousetrap, which is as it should be...A good example is the Prevnar vaccine. The Prevnar vaccine, without any government mandates, was the best selling new drug/biological in 2001. Wyeth can't make the product fast enough to satisfy public demand...In any given year, only about one quarter of the US population has voluntarily chosen to purchase and consume flu vaccine of any kind. Only when government interferes and mandates use of a vaccine or subsidizes manufacturers of vaccines is America's free enterprise system not allowed to work as it should. At the end of the day, the public should not be forced to use a product it does not want...There were very good reasons why the FDA did not approve FLUMIST for use in children under five or adults over 50. MedImmune and Wyeth both know why. MedImmune is wise to read the writing on the wall rather than ask for government bailout of a vaccine that the public, for whatever reasons, obviously does not want."
►February 12, 2004 -
Drug company greed hurts effort on flu (requires registration) - opinion -
The Central Florida Future - "What
Bush's privatization plan would essentially do to the U.S. pharmaceutical
landscape is put our unenviable drug dependency more in the hands of companies
whose sole interests are profits. That almost definitely will result in a drop
in vaccine availability nationwide."
►February 12, 2004 -
Flu Vaccine Makers Say Gov't Must Increase Demand - Reuters, UK - "Vaccine
makers can not guarantee enough future supplies of flu vaccines unless the
government can help ensure profitability, drug company officials told U.S.
Congress on Thursday...Unless the market is expanded -- either by ensuring that
more at-risk people get vaccinations for influenza or simply more people in
general, companies have little incentive for innovation, the executives
said...'Raising demand is key to raising supply,' Howard Pien, president and
chief executive officer of Emeryville, Calif.-based Chiron Corp. said...'A
universal recommendation... will in turn provide the impetus on the part of
vaccine manufacturers to increase their production capacity to meet routine
demand,' James Young, president of Research and Development at MedImmune, said."
Comment: Can this really be happening? Are they going to get away with it? If history is any judge, they just well may. For more on the flu and the flu vaccine, go to Dr. Sherri Tenpenny's articles at www.redflagsdaily.com .
►January 15, 2004 - Jury Still Out On Flu Vaccine - HealthDay via The Atlanta Journal-Constitution - "The CDC is still urging flu vaccination, especially for such high-risk persons as children and older people, because history shows that the vaccine probably is preventing the disease in many cases and reducing the incidence of complications in those who develop the disease, says Dr. Nidhi Jain, a CDC epidemiologist..."Remember, there are three different strains in the vaccine," Treanor says. "One of those strains could pop out later this year...And the record of past years in which there was a mismatch between the virus used for the vaccine and the most common strain in the population shows that the vaccine did reduce the number of infections and the potentially life-threatening complications in those who developed influenza, Jain says."
Comment: Even though the CDC says "This study does not provide data that permits an assessment of the effectiveness of TIV (trivalent inactivated vaccine) against laboratory-confirmed influenza and its complications. Additional studies to provide such data are under way. Because TIV was effective against laboratory-confirmed influenza and influenza-related complications in previous years in which it was not effective against ILI (8,9), and because influenza B and influenza A (H1N1) viruses might cause serious illness later this season, influenza vaccine continues to be recommended for persons at increased risk for influenza-related complications, their household contacts, and health-care personnel.", it is still difficult to see how the CDC can continue to recommend this vaccine. This is particularly true given that their own preliminary studies confirm that it appears the vaccine is not likely to be protective. (After all, it is not as if there are no adverse flu vaccine-associated reactions reported to VAERS. Between 1990 and now there have been 20,174, probably at a minimum representing over 200,000.) That is, it is hard to fathom unless they view their primary job to be protecting the vaccine manufacturers rather than the public. And unless they have conducted studies comparing those who were vaccinated to those who were not vaccinated against the flu (breaking it down by "never vaccinated" and all the various vaccine combinations), there is simply no basis for the argument that a mismatched flu vaccine offers at least some protection against the flu.
►February 12, 2004 - Call for bird vaccinations - Chickens may get the jab to stop spread of bird flu. - Nature
Comment: But if a recent article in New Scientist is correct, vaccinations may be part of the problem, rather than part of the solution.
►February 11, 2004 - Avian Influenza - Advice from The Centers for Disease Control and Prevention - Travel VideoTelevision News
►February 11, 2004 - Spinoff of vaccine firm raises doubts on flu plan - Canadian Press via the Toronto Star - "The backbone of the federal pandemic flu plan, which will be released Thursday, is a contract to buy enough vaccine to inoculate all Canadians. But a question mark is hanging over the future of the vaccine manufacturer, leaving some to wonder how firm that backbone really is...A crucial feature of the federal plan is that Canada has secured a domestic supplier of vaccine, Shire Biologics of Laval, Que. Having a domestic supplier ensures flu shots bought, paid for and destined for Canadian arms couldn't be nationalized by another government desperate to protect its own citizens from an influenza pandemic sweeping the globe...But the British company that owns Shire Biologics is in the process of divesting itself of the vaccine manufacturer, a move that has drawn purchase offers from a number of other companies. That situation is prompting questions about how iron-clad the procurement contract is."
►January 5, 2004 - Nasal Flu Vaccine Safe for Kids - HealthDay via The Atlanta Journal-Constitution - "Here's some good news for parents who have to drag their kids kicking and screaming to get their annual flu shot...It turns out an influenza virus vaccine delivered as a nasal spray protects healthy children against certain strains of influenza, says a report in the January issue of The Archives of Pediatrics & Adolescent Medicine...Doctors at the Scott & White Memorial Hospital and Clinic in Temple, Texas, found children who received the nasal vaccination were protected against influenza infection during the 2000 flu epidemic."
Comment: Note that the results of this study do not mean the nasal flu vaccine was protective against this year's flu. Nor, in all likelihood, was it protective against this year's flu. (Why they failed to make sure parents understood this, is beyond me.)
►February 11, 2004 - Vaccines Stockpile urged - New Zealand warning - Otago Daily Times - "Two University of Otago graduates have warned New Zealand must ready itself for the bird flu by stockpiling vaccines for the deadly disease...Dr Robert Webster and Dr Richard Webby - who now head a Memphis-based World Health Organisation laboratory for animal influenza viruses - have said there is a worldwide shortage of two drugs which can help fight bird flu, One News reported last night."
►February 11, 2004 - Genetic analysis probes bird flu's history - New Scientist - "Recent work also reveals that the virus has been mutating rapidly in response to 'unusual selective pressure' from an unknown source. Prominent virologists have warned that widespread vaccination of poultry against bird flu - as has been the case in China - could have this effect."
Comment: How many new diseases are a result of vaccination? How many researchers are even looking into this possibility? How many diseases caused by vaccination are we now seeking to develop vaccines to prevent in the future? How many of these new diseases are more serious, with humans less adapted to them than the original disease for which the vaccine was designed?
►February 11, 2004 - Thailand rejects WHO criticism over handling of bird flu outbreak – www.channelnewsasia.com
►January Supplement 1, 2004 - Vaccination for pandemic influenza: a six point agenda for interpandemic years. - journal article (Pediatric Infectious Disease Journal)
►February 11, 2004 - A timely account of the 1918 flu pandemic - The Boston Globe
►February Supplement 2, 2004 - Pneumococcal resistance in perspective: how well are we combating it? - journal article (Pediatric Infectious Disease Journal)
►February 2004 -
Safety of cold-adapted live attenuated influenza vaccine in a large cohort of
children and adolescents - journal article
(Pediatric Infectious Disease Journal)
►February 11, 2004 -
Bird flu
two years to control: WHO - The deadly bird flu sweeping Asia could take two
years to get under control, the World Health Organization has warned. - CNN
►February 10, 2004 -
Tests Show
Avian Flu on Second Del. Farm - Delaware Officials Order Quarantine, Chicken
Slaughter After Second Bird Flu Case Found - AP via ABC News
►February 10, 2004 -
Bird flu linked to 1918 pandemic - The Telegraph, UK
►February 10, 2004 -
Bird
Flu Rattles U.S. Poultry Officials (registration required) - AP via The
Kansas City Star
►February 9, 2004 - WHO says bird flu problem may take couple of years to contain - Canadian Press via http://cnews.canoe.ca
►February 9, 2004 - With diseased animals, disposal isn't simple - New York Times News Service via www.abs-cbnnews.com
►February 9, 2004 - Wyeth Sniffs at U.S. Warning That Grounded Flu Drug Sales - Financial Times via www.immunizationinfo.org (abstract)
►February 9, 2004 - 'Respiratory etiquette' cuts spread of disease - Evansville Courier & Press via Healthy News
►February 9, 2004 - Where's the Flu Bug? - www.kndu.com - "This is usually the time of the year when the flu bug is hitting the hardest...But after an early start, and a run on flu shots, we haven’t seen the big outbreak that was feared. It came early, and it looks like it might have left just as quickly."
►February 9, 2004 - As bird flu spreads, global health weaknesses are exposed - NY Times News Service via www.abs-cbnnews.com
►February 10, 2004 - More Singaporeans taking flu inoculations - Channel NewsAsia via Yahoo!
►February 10, 2004 - Despite drop in flu, vaccinations still encouraged - The Robesonian - "Even though the worst of the national flu epidemic seems to have passed, the Robeson County Health Department is urging at-risk individuals to take advantage of the limited number of flu vaccines still available...Bill Smith, health director, said flu season typically runs through March, and data from the past two winters show that flu activity has peaked during February and March."
Comment: And in spite of the fact that they apparently do not work, even according to the CDC.
►February 10, 2004 - WHO wants more tests to ensure bird flu cannot be passed among humans - Channel News Asia
►February 10, 2004 - WHO raps Asia over handling of bird flu crisis as China reports new cases - AFP via www.channelnewsasia.com
►February 10, 2004 - EU warns Asian countries against bird flu cover-up - EU Business
►February 9, 2004 - Confidence the key in fight against bird flu - China Daily - "As the highly contagious bird flu virus spreads across Asia, the affliction has become embedded in the popular lexicon through media reports and ordinary conversation...The new crisis appeared when many in the region were still reeling from the bitter memories of SARS (severe acute respiratory syndrome), and it has unavoidably triggered public panic in some places."
►February 9, 2004 - China official threatens HK media over flu reports - Reuters AlertNet - "A Chinese official has threatened to take legal action against Hong Kong's journalists over their reporting of bird flu outbreaks on the mainland, newspapers here reported on Monday...Zhong Yangsheng, executive vice governor of China's southern Guangdong province, also insisted there was no outbreak in the province's Chaoan county although it has been confirmed by the central government."
►February 8, 2004 - Wyeth says warnings hurt flu drug sales - Financial Times - "Wyeth has blamed the US authorities in part for the poor performance of FluMist, its flu vaccine...Robert Essner, chief executive of Wyeth, said warnings by the government and health groups had triggered 'folklore' that the weakened, but live flu virus used in FluMist could be transmitted to other people, causing sickness. He said Wyeth was conducting a comprehensive review of its strategy for the product."
►February 8, 2004 - No human-to-human link, says WHO - Follow-up tests on Vietnamese sisters show no human genes in virus, meaning it has not mutated to a more lethal form - The Straits Times
►February 9, 2004 - WHO says Vietnam flu is not new - Taipei Times - "The WHO said the bird flu that killed two people in Vietnam was not a new, more contagious strain, and officials here rejected claims that pigs now have the virus...Meanwhile, China has confirmed three more outbreaks among birds...The UN agency said on Saturday that 'reassuring' test results from the two Vietnamese sisters, who died earlier this month, show 'both viruses are of avian origin and contain no human influenza genes.'"
►February 3, 2004 - Ferret shortage may cause a 'bottleneck' in pandemic vaccine production: WHO - Canadian Press via www.canada.com - "Efforts to create a prototype vaccine to protect humans in the event of a H5N1 influenza pandemic may be facing an unusual problem: a shortage of flu-free ferrets...The head of the World Health Organization's global influenza program says efforts to create what's called the viral seed for a pandemic vaccine are moving along at the expected pace, but there's been a delay in getting the ferrets needed to test whether the genetically altered virus is safe to work with."
►February 3, 2004 - Asia should change lifestyle to avoid bird flu: WHO - Xinhuanet via China View
►February 2, 2004 - Public health expects fewer vaccines next year - The Gillette News-Record
January 26 - February 8, 2004 (2 weeks combined due to illness)
►February 7, 2004 - Milder bird flu strain hits USA - AP via The Statesman - "Delaware officials ordered the destruction of some 12,000 farm chickens yesterday after confirming that the flock was infected by avian influenza. But state agriculture secretary Mr Michael Scuse said the flu strain is different from the one that has devastated Asian poultry stocks and killed at least 16 people...Mr Scuse said the flu strain found in the USA posed no threat to human health."
►February 7, 2004 - WHO says no human tranmission of bird flu yet - www.ctv.ca - "U.S. officials scrambled to contain the first case of bird flu found in the United States Saturday while some good news came out of Asia...The World Health Organization ruled out human-to-human transmission of the virus there."
►February 8, 2004 - Bird flu hits U.S., poultry culled S. Korea ban on U.S. chickens 'premature' - Delaware's agriculture secretary says it is "way premature" for South Korea to ban U.S. poultry products after a strain of bird flu not known to affect humans was found on a farm in the state. - CNN
►February 4, 2004 - Is the flu through? - This year's flu season behaved a lot like the month of March - in like a lion and out like a lamb. But is it really over? - News of Delaware County
►February 7, 2004 - Bird flu challenges the world's vaccine makers - Canada's main provider is 'ready to turn production on a dime' from regular flu to a pandemic vaccine, LEONARD ZEHR writes - The Globe and Mail
►February 7, 2004 -
Future of FluMist vaccine in doubt after slow sales - Nasal spray, developed at U-M, didn't catch on - The Ann Arbor News►February 7, 2004 - Scientists probe deadly 1918 flu virus - www.channelnewsasia.com - "British scientists say they have solved the mystery of the world's deadliest flu epidemic in 1918 - how the virus was able to jump from birds to humans - in a breakthrough that could help efforts to control the current outbreak of bird flu in Asia."
►February 7, 2004 - Human bird flu vaccine closer - Labs in Atlanta, Memphis pass major milestone - The Atlanta Journal-Constitution - "Scientists at the U.S. Centers for Disease Control and Prevention in Atlanta and St. Jude Children's Research Hospital in Memphis said their achievement — breaking the virus apart to remove its most virulent elements and reassembling it — is but one step of many on the road to a bird flu vaccine...If every remaining step goes as well as possible, they said, it will still take four to six months of lab work, testing and manufacturing before a safe, approved vaccine can be made and sold."
►January 26, 2004 - Hospitalization During Flu Season Not Tied to Adverse Pregnancy Outcomes (requires registration or subscription) - Reuters Health via Medscape - "Pregnant women with respiratory hospitalizations during influenza season are not at increased risk for adverse maternal or neonatal outcomes, new research indicates. Asthmatic patients were nearly 11 times more likely to be hospitalized than women without any comorbidities."
Comment: What do you bet there is no revision of new guidelines recommending that pregnant women be vaccinated against the flu, now that this information has become available? (Even if confirmed by a larger study.)
►February 5, 2004 - Australian scientists hope to have bird flu vaccine within months - Australian scientists said Thursday they hoped to produce a trial vaccine within months to immunise chickens at risk of contracting deadly bird flu. - Manilla Bulletin Online
►February 8, 2004 - Dr. Abdullah Al Madani: Bird flu breeds hot debate on human safety vs economic gains - Gulf News Online - "While the flu epidemic threatens Asia's multi-billion-dollar poultry industry, the real danger lies in the threat to human life. Scientists argue that genes from the H5N1 virus could get scrambled with genes from H3N2, the virus responsible for human influenza, causing a serious threat to millions of people, as the human immune systems is not designed to cope with bird flu...The fact that the Far East is a densely populated region, has a huge number of domestic birds, and a large poultry industry makes the anxiety even more acute."
►February 8, 2004 - Bird Flu Twice as Deadly as Last Outbreak-Doctor - Reuters - "
'The data suggests it (mortality rate) is in the range of 60 to 70 percent, so we are quite shocked by this,' David Hui, a specialist in respiratory medicine at the Chinese University of Hong Kong, told Reuters Television. Last time (in 1997), the mortality rate was 30 percent.'"►February 6, 2004 - Researchers Determine Reason For Deadly Spread Of 1918 Influenza - Howard Hughes Medical Institute via Science Daily - "The explosive spread of the influenza virus during the 1918 pandemic that killed some 20 million people worldwide was likely enabled by the unique structure of a protein on the virus's surface, researchers are reporting. The newly determined structure of the viral protein reveals that the 1918 strain of influenza underwent subtle alterations that enabled it to bind with deadly efficiency to human cells, while retaining the basic properties of the avian virus from which it evolved...According to the researchers, although their findings do not apply to the new virulent strain of avian flu that is threatening to spread, they do emphasize how subtle alterations in the influenza virus's infectivity could spawn a major epidemic."
►February 7, 2004 - Bird flu: Not a food-borne virus - For an hour yesterday, National Development Minister Mah Bow Tan fielded MPs' questions on bird flu, ranging from whether it was safe to eat half-cooked eggs to whether Jurong Bird Park should be shut down. - The Straits Times - "Is it safe to eat half-boiled eggs? This is not a food-borne virus. It transmits and infects through close contact with fecal material or mucus from infected poultry. So there is really no danger from eating well-cooked, well-prepared food. Any time you eat something that's half-cooked or raw, you are running a risk."
Comment: Wouldn't you have to be very careful re: contamination and spread from handling the eggs, however?
►February 6, 2004 - Commentary: Float and termination of rumors about bird flu - Bird flu has been attacking and harassing some Asian countries and regions, over the past few days, suspected and highly pathogenic bird flu epidemic has also occurred in many Chinese provinces and cities one after another. Meanwhile, rumors about bird flu have surfaced one after another at home and abroad. However, this time rumors have found no market. - People's Daily, China
►December 2003 - Evaluation of clinical and immunological effects of inactivated influenza vaccine in children with asthma - journal article (Pediatric Allergy and Immunology)
►February 2004 - Impact of pneumococcal and influenza vaccines on otitis media - journal article (Current Opinion in Pediatrics)
►February 7, 2004 - WHO Examines Bird Flu Transmission - World Health Organization Rules Out Person-To-Person Transmission of Bird Flu in Vietnam - AP via ABC News - "The World Health Organization said the bird flu virus that killed two Vietnamese sisters did not contain human genes, meaning there is still no sign the virus sweeping Asia has mutated into a new, more contagious form."
►February 7, 2004 - Israeli vaccine on trial that might foil the flu - Jerusalem Post Internet Edition - "If clinical trials on an Israeli-developed nose drop vaccine for influenza prove as successful as those that are nearing completion on mice, people of all ages will be protected for five years against all present and future strains of the flu."
►February 7, 2004 - Bird Flu Detected in U.S. as Virus Wanes in Asia - Reuters - "The first case of bird flu appeared in the United States just as hard-hit Thailand said it hoped to clear the last outbreak of an epidemic that has killed 18 people and decimated poultry flocks across Asia...More than 12,000 chickens have been quarantined in the U.S. state of Delaware and are due to be destroyed after they were found to have a strain of the virus which differs from the one that has killed people in Thailand and Vietnam, the Delaware State News reported on its Web site."
►February 6, 2004 - `Arrogant' Yeoh ignores bird flu risk: lawmakers - The Standard, China - "Secretary for Health, Welfare and Food Yeoh Eng-kiong was accused by legislators yesterday of arrogantly ignoring and downplaying the threat of bird flu...They said his inaction in the face of a possible global outbreak that could spread to humans showed he had not learned the lessons from last year's Sars outbreak that claimed 299 lives."
►February 2004 - Further reflections on the recent influenza epidemic (requires registration) - A new-school approach to an old-school problem revisited. - Infectious Diseases in Children
►February 6, 2004 - Virus threat dwarfs SARS - The Australian - "THE Australian scientist who led the World Health Organisation fight against SARS in China warned yesterday that Asian bird flu was "1000 times worse" than that deadly outbreak...John McKenzie said the H5N1 strain of avian influenza, which has killed 17 people in Southeast Asia and forced the slaughter of millions of birds, represented 'the worst scenario possible' for a worldwide flu pandemic."