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West Nile vaccine in the works
Scientists say protection could be available in three years

ASSOCIATED PRESS
WASHINGTON, Sept. 24 — Small studies of a possible vaccine against West Nile virus could begin within months and a vaccine for the people most at risk of dying from the virus could be available in three years, federal scientists told Congress Tuesday.


 

     
     
       
   
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So far, the Centers for Disease Control and Prevention has counted nearly 2,000 infections and 94 deaths.

 
       THE EXPERIMENTAL vaccine is built on the long-used vaccine against yellow fever, a cousin of the West Nile virus. Thus scientists are hopeful it will prove safe to use, as well as provide protection for the elderly, who are at highest risk for getting encephalitis if they become infected with the West Nile virus.
       West Nile virus first appeared in the United States in 1999 but caused an epidemic this year. So far, the Centers for Disease Control and Prevention has counted nearly 2,000 infections and 94 deaths as of Monday.
       But only one out of every 150 to 200 people who are infected actually become seriously ill. Most have either mild flu-like symptoms or no symptoms at all.
       
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       That has actually complicated scientists’ ability to tell if West Nile can be transmitted through the blood supply. A recent infection in a woman who received blood from a West Nile infected donor suggests that can happen, but the risk is believed low. Still, the Food and Drug Administration is pushing blood banks to develop tests that would detect the virus in donated blood.
       Studies in animals suggest that immunity to other similar viruses, such as yellow fever and dengue fever, also provides protection against West Nile virus, said Dr.
 
  Health Library: Infectious diseases

 
 
       Anthony Fauci of the National Institute of Health. Based on that knowledge, scientists have put genes from West Nile virus into the structure of the yellow fever vaccine. The small biotechnology company Acambis plans to begin small safety testing of this new vaccine shortly, Fauci told a Senate hearing Tuesday.
       Meanwhile, people’s best defense is to wear mosquito repellent containing the chemical DEET and to eliminate all standing water around their homes, which is where mosquitoes breed.
       “Most mosquitoes transmitting this virus live in the suburban back yard, “ said CDC director Dr. Julie Gerberding.
 
 
 
 

The West Nile virus is a mosquito-borne flavivirus common in Africa, West Asia and the Middle East. It was first seen in the eastern United States in the summer of 1999.


Source: CDC; The Associated Press
Printable version


       
       
       © 2002 Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
       

 
     
       
   
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