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"New Vaccines for the Prevention of Tuberculosis"Immunization Newsbriefs (c) Copyright Information Inc., Bethesda, MD. Brought to you by the National Network for Immunization Information (NNii). Visit NNii's new website at http://www.immunizationinfo.org.
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September 13, 2002
U.S. IMMUNIZATION NEWS
"New Vaccines for the Prevention of Tuberculosis" Clinical Infectious Diseases (www.journals.uchicago.edu/CID/home.html) (08/15/02) Vol. 35, No. 4, P. 465; von Reyn, C. Fordham; Vuola, Jenni M.
While Mycobacterium bovis, or bacille Calmette-Guerin, has been administered to newborns for generations for the prevention of childhood tuberculosis, its effectiveness as a preventative against reactivation pulmonary disease or HIV-associated tuberculosis is minimal. A number of promising candidates for a more effective tuberculosis have been created and some are in development, but the lack of a preventive for such a wide range of pulmonary diseases highlights the importance of discovering such a vaccine quickly. Researchers are studying a variety of vaccine techniques, including using attenuated or enhanced whole-cell live vaccines, whole-cell inactivated products, and subunit, DNA, and prime-boost vaccines. A few have even demonstrated effectiveness into animal trials, but such a vaccine will take years to reach the market. The delay will be due to the fact that there has been no marker found to identify immunity against tuberculosis. As a result, any truly effective vaccine will require going through years of testing and follow-up data gathering to determine its effectiveness in preventing tuberculosis in patients. ALL INFORMATION, DATA, AND
MATERIAL CONTAINED, PRESENTED, OR PROVIDED HERE IS FOR GENERAL INFORMATION
PURPOSES ONLY AND IS NOT TO BE CONSTRUED AS REFLECTING THE KNOWLEDGE OR OPINIONS
OF THE PUBLISHER, AND IS NOT TO BE CONSTRUED OR INTENDED AS PROVIDING MEDICAL OR
LEGAL ADVICE. THE DECISION WHETHER OR NOT TO VACCINATE IS AN IMPORTANT AND
COMPLEX ISSUE AND SHOULD BE MADE BY YOU, AND YOU ALONE, IN CONSULTATION WITH
YOUR HEALTH CARE PROVIDER.
DISCLAIMER: All information, data, and material contained, presented, or provided here is for general information purposes only and is not to be construed as reflecting the knowledge or opinions of the publisher, and is not to be construed or intended as providing medical or legal advice. The decision whether or not to vaccinate is an important and complex issue and should be made by you, and you alone, in consultation with your health care provider.
Copyright 2012 by Vaccination News, A Non-Profit Corporation. All Rights Reserved. This content may not be copied unless permission in writing from Sandy Gottstein has been obtained. 
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 "A foolish faith in authority is the worst enemy of truth." -- Albert Einstein, letter to a friend, 1901 "I know of no safe depository of the ultimate powers of the society but the people themselves, and if we think them not enlightened enough to exercise control with a wholesome discretion, the remedy is not to take it from them, but to inform their discretion by education." -- Thomas Jefferson, letter to William C. Jarvis, September 28, 1820 "What's the point of vaccination if it doesn't protect you from the unvaccinated?" -- Sandy Gottstein "Who gets to decide what the greater good is and how many will be sacrificed to it?" -- Sandy Gottstein |