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NEW FEATURES THIS WEEK

MEDSCAPE ORIGINAL ARTICLES
PEDIATRICS JOURNAL SCAN, AUGUST 2002
Featured this month: erythromycin and pyloric stenosis; tonsillectomy for recurrent throat infection; and epilepsy.
Medscape Pediatrics 4(2) 2002


DYSPNEA DUE TO VOCAL CORD DYSFUNCTION AND OTHER LARYNGEAL SOURCES
A high index of suspicion is needed to carefully unravel a patient's symptom complex and pinpoint a diagnosis of pathology in the larynx.
Medscape Allergy 2(2) 2002


ASK THE EXPERT - TREATMENT OF SYSTEMIC ONSET JUVENILE RHEUMATOID ARTHRITIS
Should IVIG or MTX be the next step for a 6-year-old boy with JRA who has failed to respond to first-line treatments?
Medscape Rheumatology 4(2) 2002


MONTHLY SUMMARIES OF NURSING RESEARCH: AUGUST 2002
Highlights include helping children change their temperament, parental worry about hospitalized children, behavioral problems in macrosomic neonates, and parents coping with the violent death of a child.
Medscape Nurses 4(2) 2002


PEDIATRIC ID JOURNAL
CHILDHOOD VACCINATIONS AND RISK OF ASTHMA
There is no association between DTP, OPV, or MMR vaccine and the risk of asthma.
Pediatr Infect Dis J 21(6) 2002


MMWR
DELAYED DIAGNOSIS OF FRAGILE X SYNDROME - US, 1990-1999
Prompt diagnosis enables children to receive early intervention services and families to receive genetic counseling.
MMWR 51(33) 2002


NONFATAL SPORTS- AND RECREATION-RELATED INJURIES TREATED IN EMERGENCY DEPARTMENTS - US, JULY 2000-JUNE 2001
An estimated 4.3 million sports- and recreation-related injuries are treated each year in US emergency departments.
MMWR 51(33) 2002


EMERGING INFECTIOUS DISEASES
NOVEL MEASLES VIRUS GENOTYPE, EAST TIMOR AND AUSTRALIA
Vaccination of support staff is likely to decrease transmission of measles in industrialized countries.
Emerg Infect Dis 8(7) 2002


OTHER JOURNALS
INTESTINAL TRANSPLANTATION IN PEDIATRIC PATIENTS
Intestine transplantation has evolved into a feasible alternative for children with permanent intestinal failure and life-threatening complications from TPN.
Prog Transplant 12(2) 2002


EVALUATION OF A SINGLE-TUBE MULTIPLEX PCR SCREEN FOR DETECTION OF COMMON ALPHA-THALASSEMIA GENOTYPES IN A CLINICAL LABORATORY
This multiplex approach was more sensitive than the HbH prep for detecting all alpha-thalassemia genotypes, particularly alpha -thalassemia
Am J Clin Pathol 118(1) 2002


CLINICAL QUIZ: YOUNG GIRL WITH RIGHT UPPER QUADRANT ABDOMINAL PAIN
What does the abnormality most likely indicate?
Appl Radiol Online 1(1) 2002


ATTENTION-DEFICIT/HYPERACTIVITY DISORDER: AN UPDATE
Older individuals typically manifest disorganization and impulsivity more than hyperactivity.
South Med J 95(7) 2002


WEIGHT CONTROL PRACTICES AND DISORDERED EATING BEHAVIORS AMONG ADOLESCENT FEMALES AND MALES WITH TYPE 1 DIABETES
This study examines the prevalence of specific weight-control practices/disordered eating behaviors among diabetic adolescents.
Diabetes Care 25(8) 2002
 

BIPOLAR ILLNESS IN THE PRIMARY CARE SETTING
Refine strategies for successful interventions. Review "Beyond
Antidepressants: Bipolar Spectrum Illness Presenting as
Complicated or Refractory or Mood Disorders in Primary Care,"
a featured CME activity in the Bipolar Disorder Resource Center.


 

NEWS

ASTHMA & ALLERGY
EXPOSURE TO SEVERAL ANIMALS IN INFANCY MAY REDUCE ALLERGY RISK LATER IN LIFE
Infants who are exposed to two or more cats or dogs during the first year of life appear to be protected against several common allergies later in childhood, according to a report published in the August 28th issue of JAMA.
Reuters Health Information 2002


INHALED FORMOTEROL THERAPY EFFECTIVE FOR PERSISTENT ASTHMA IN CHILDREN
Inhaled formoterol dry powder is an effective treatment for children with asthma that fails to respond to anti-inflammatory therapy, according to a report published in the August issue of the Annals of Allergy, Asthma, and Immunology.
Reuters Health Information 2002


DIABETES
ORAL GLUCOSE GIVEN DURING SUBCUTANEOUS INJECTIONS IS ANALGESIC IN PRETERM INFANTS
A small dose of oral glucose has an analgesic effect when given to very preterm neonates.
Reuters Health Information 2002


TEENAGE GIRLS WITH TYPE 1 DIABETES OFTEN EXHIBIT THYROID AUTOIMMUNITY
The prevalence of thyroid autoantibodies increases with increasing age of children or adolescents with type 1 diabetes, particularly in girls between the ages of 15 and 20, German researchers report.
Reuters Health Information 2002


ISLET TRANSPLANTS ALLOW MORE INSULIN-INDEPENDENCE IN DIABETICS
New sources include porcine cells, non-heart beating donors, and marginal donor cells preserved with perfluorocarbon.
Medscape Medical News 2002


'WRISTWATCH' GLUCOSE MONITOR APPROVED BY FDA FOR CHILDREN, ADOLESCENTS
The US FDA said on Tuesday that it has approved Cygnus Inc.'s GlucoWatch Biographer, a noninvasive blood glucose monitoring device worn like a watch, for use in children and adolescents with diabetes.
Reuters Health Information 2002


INFECTIOUS DISEASES
ROTAVIRUS INFECTION IN INFANTS PROTECTS SUBSTANTIALLY AGAINST REINFECTION
Natural rotavirus infection appears to confer considerable protection against subsequent rotavirus reinfection and diarrhea, according to a report in the September 1st issue of The Journal of Infectious Diseases.
Reuters Health Information 2002


INCREASED INTERFERON-GAMMA PRODUCTION IN HIV-INFECTED CHILDREN ASSOCIATED WITH VIRAL SUPPRESSION
HIV-1 suppression in infected children is associated with increased production of IFN-gamma and with decreased rates of IL-10 production, according to a report in the August Journal of Allergy and Clinical Immunology.
Reuters Health Information 2002


SCHOOL-BASED HIV PREVENTION TRIALS FEASIBLE IN SUB-SAHARAN AFRICA
There are methodological and ethical challenges to conducting trials to determine the effectiveness of adolescent sexual health interventions in preventing HIV transmission.
Reuters Health Information 2002


PSYCHIATRY & NEUROLOGY
NEONATAL SEIZURES RARELY DUE TO INTRAPARTUM HYPOXIA
Seizures in newborns are only rarely caused by lack of oxygen during delivery, according to a report published in the August issue of the Journal of Maternal-Fetal and Neonatal Medicine.
Reuters Health Information 2002


DRY BED TRAINING SEEMS TO IMPROVE BEHAVIORAL PROBLEMS OF ENURETIC CHILDREN
It is not necessary to treat enuretic children for any emotional or behavorial problems they may have prior to treating them for bedwetting, new study findings suggest.
Reuters Health Information 2002


NEUROPSYCHIATRIC MANIFESTATIONS VERY COMMON WITH PEDIATRIC ONSET SLE
Almost all patients with pediatric onset systemic lupus erythematosus eventually develop neuropsychiatric manifestations, and these conditions can often be life-threatening.
Reuters Health Information 2002


MOTOR TICS MORE COMMON AMONG CHILDREN THAN PREVIOUSLY THOUGHT
Nearly one in four elementary schoolchildren experience motor tics, but in most cases the tics are mild, brief and not associated with behavioral problems, according to a report published in the August issue of Pediatrics.
Reuters Health Information 2002


PRENATAL & NEONATAL
HIGH-FREQUENCY OSCILLATORY VENTILATION OF LITTLE BENEFIT IN PREMATURE INFANTS
Conventional low tidal volume ventilation is preferable except at a few select centers.
Medscape Medical News 2002


FATTY ACID INTAKE DURING LATE PREGNANCY INFLUENCES NEONATAL SLEEP PATTERNS
Newborns whose mothers consume adequate amounts of docosahexaenoic acid during the last 3 months of pregnancy exhibit healthier sleep patterns than others, US researchers report.
Reuters Health Information 2002


NEONATES MORE LIKELY TO DIE IF BORN AT HOME OR IF HOME DELIVERY WAS ATTEMPTED
The risk of neonatal death after home birth, or after birth at a hospital following urgent transfer from home, is almost twice as high as after planned hospital birth, according to a review of data from Washington State birth certificates from 1989 to 1996 published in the August issue of Obstetrics
Reuters Health Information 2002


TRANSPLANT
T-CELLS RECONSTITUTED IN SCID FETUS BY IN UTERO FETAL LIVER CELL TRANSPLANTATION
In a male fetus with X-linked severe combined immunodeficiency, the in utero transplantation of cryopreserved fetal liver cells led to complete T and NK cell reconstitution, researchers report.
Reuters Health Information 2002


SPLIT LIVER TRANSPLANTATION SUCCESSFUL IN CHILDREN
Split liver transplantation using the ex situ technique has a good overall outcome in children, with acceptable morbidity, UK researchers report.
Reuters Health Information 2002


CANCER
MATERNAL VITAMIN USE SIGNIFICANTLY REDUCES NEUROBLASTOMA RISK
Women who take multivitamins before or during pregnancy significantly reduce the risk of their offspring developing neuroblastoma, researchers report in the September issue of Epidemiology.
Reuters Health Information 2002


MORTALITY LOW BUT RECURRENCE HIGH WITH THYROID CANCER IN CHILDREN
A review of the records of 56 children with thyroid carcinoma at Washington University in St. Louis, Missouri, conducted by Dr. Perry W. Grigsby and colleagues, showed an overall survival rate of 98% (one death) but a recurrence rate of 34%.
Reuters Health Information 2002


OTHER NEWS
WBC SCAN IMPROVES DIAGNOSIS IN SUSPECTED APPENDICITIS
The high accuracy and negative predictive value may reduce the observation period and unnecessary surgery.
Medscape Medical News 2002



 

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