FLU PILL
TO END NEEDLE MISERY
|
Sep 18 2002
|
|
Ready in months, says Scots expert |
|
|
A NEW pill could soon make flu jabs
obsolete.
Thousands of people shy away from flu
immunisation because they are scared of needles.
But Strathclyde University immunologist
Professor Bill Stimson claims a micro- capsule containing the vaccine
could be ready in months.
He says it is easy to swallow and as
effective as injecting the vaccine into the bloodstream.
Professor Stimson flew to the US yesterday
to meet potential commercial partners.
If successful, the pill will help tackle the
bed-blocking crisis that has crippled the NHS during winter flu
epidemics.
It is also expected to become a "platform
technology" for other vaccines - the cost of injections is higher than
vaccines which can be taken orally.
Professor Stimson said: "Any vaccine that
can be taken orally is better than an injection because so many people
dislike them.
"The number of elderly people who come
forward for the flu injection has increased but far too many opt out.
"Go into hospital in winter and beds are
still blocked by elderly people who have caught the flu.
"That is what I would like to tackle in the
first instance.
"It's much swifter and much easier to give
someone a small tablet to pop into their mouth and wash it down with
water."
Oral vaccines have been problematic because
they contain proteins which are broken down and destroyed in the
stomach.
But Professor Stimson and his colleagues
devised a new method.
The new carrier, a tiny capsule, is made of
small fat-like particles which can't be dissolved in the stomach. The
vaccine passes through unscathed into the small intestine.
The researcher explained: "The micro-capsule
is designed to dissolve in the small intestine.
"The vaccine itelf then binds on to the
small intestine and is absorbed into the bloodstream.
"The results of the vaccination using this
method are equal to the injections currently used.
"We have about six months work left before
we will be able to prove that this concept works.
"We must ensure that the finished product is
exactly right."
Dr Jim McMenamin, of the Scottish Centre for
Infection and Environmental Health, said: "Alternative ways of
administering the vaccine are regarded as a way of improving uptake.
"There is a large group who don't want to
have needles put in their arms and that is a problem.
"An oral vaccine that is proven to work is
very attractive."
Flu reached epidemic levels in Scotland in
winter 1999 with 839 cases per 100,000 people. |