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Infect Dis Clin North Am 2001 Mar;15(1):143-153 |
Issues related to the decennial
tetanus-diphtheria toxoid booster recommendations in adults.
Gardner P.
Department of Medicine, State University of New York at Stony Brook, Stony
Brook, New York, USA.
In terms of disease prevention, reduction of adverse reactions, and cost
benefit studies, a strong case can be made for a policy that focuses on
assuring high levels of primary immunization with tetanus and diphtheria (Td)
toxoids and abandons the decennial Td booster in favor of a single midlife
booster at age 50-65 years. The addition of acellular pertussis antigens to Td
for routine use in adults has potential problems in terms of schedule, cost,
and possible adverse reactions. Careful risk/benefit studies are necessary to
evaluate its effectiveness and priority.
Publication Types:
·
Review
·
Review, tutorial
PMID: 11301812 [PubMed - indexed for MEDLINE]
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