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J Rheumatol 1997 Oct;24(10):2047-2050 |
Different course of reactive arthritis in two
HLA-B27 positive brothers with fatal outcome in one.
Yli-Kerttula T, Mottonen T, Toivanen A.
Department of Medicine, Turku University, Finland.
During an outbreak of Yersinia pseudotuberculosis III, one of two HLA-B27
positive brothers developed reactive arthritis (ReA), mild at first, but later
severely destructive and ultimately fatal. The reactivation of ReA was possibly
triggered by an oral polio vaccine. The cause of death was severe secondary
amyloidosis. The other brother was exposed to the same Y. pseudotuberculosis
strain but did not develop any disease during or after the outbreak. However,
he later developed ReA due to a Salmonella infection, with a benign course.
PMID: 9330954 [PubMed - indexed for MEDLINE]
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