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Wall Street Journal (www.wsj.com)
(10/09/02) P. B3C; Ahlberg, Erik
Britain's PowderJect and Acambis, and
Gaithersburg, Md.-based Antex Biologics are on a short list of drug makers
working on vaccines to combat the symptoms that cause travelers' diarrhea.
PowderJect already has a drinkable vaccine on the market called Dukoral that
targets the enterotoxigenic E. coli (ETEC) bacteria--one of several bacteria
known to induce travelers' diarrhea. Dukoral has been sold at travel clinics in
Sweden
and Norway for several years, and
PowderJect is now working to get U.S. Food and Drug Administration approval for
the product. Acambis' ETEC vaccine, tentatively called HolaVax-ETEC, combines
five of the worst strains of the ETEC bacteria into one compound. Acambis
officials said clinical trials for the vaccine will begin sometime in the next
two years, with applications to regulatory agencies in the United States and
overseas expected around 2007. Meanwhile, like PowderJect's travelers' diarrhea
vaccine, Antex Biologics' vaccine singles out specific bacterial strains, except
in this case, the strains are the campylobacter and shigella bacteria. Antex
expects to have a product within the next three to five years.
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-- Albert Einstein, letter to a friend, 1901
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"What's the point of vaccination if it doesn't protect you from the unvaccinated?"
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