Influenza vaccination induced leukocytoclastic vasculitis and
pauci-immune crescentic glomerulonephritis.
Yanai-Berar N, Ben-Itzhak O, Gree J, Nakhoul F.
Department of Nephrology, Rambam Medical Center, Haifa, Israel.
Influenza vaccination is a widely accepted practice, particularly among the
elderly and high-risk individuals. Minor and transitory side effects following
the vaccination are common, while systemic complications are infrequently
reported. We describe here a case of a patient who presented to the emergency
room with arthralgia, myalgias and purpura, following influenza vaccination.
Necrotizing vasculitis associated with pauci-immune glomerulonephritis was
observed on kidney biopsy. With increasing use of influenza vaccination,
attention should be drawn to the possible expression of systemic adverse effects
such as vasculitis and glomerulonephritis.
ALL INFORMATION, DATA, AND
MATERIAL CONTAINED, PRESENTED, OR PROVIDED HERE IS FOR GENERAL INFORMATION
PURPOSES ONLY AND IS NOT TO BE CONSTRUED AS REFLECTING THE KNOWLEDGE OR OPINIONS
OF THE PUBLISHER, AND IS NOT TO BE CONSTRUED OR INTENDED AS PROVIDING MEDICAL OR
LEGAL ADVICE. THE DECISION WHETHER OR NOT TO VACCINATE IS AN IMPORTANT AND
COMPLEX ISSUE AND SHOULD BE MADE BY YOU, AND YOU ALONE, IN CONSULTATION WITH
YOUR HEALTH CARE PROVIDER.