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Antimicrobial Agents and Chemotherapy, November 2002, p. 3641-3643, Vol. 46, No. 11
0066-4804/02/$04.00+0     DOI: 10.1128/AAC.46.11.3641-3643.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.
 

Antimicrobial Resistance in Haemophilus influenzae Isolated during Population-Based Surveillance for Meningitis in Salvador, Brazil

Joice Neves Reis,^1,2 Josilene Borges Lima,¹ Guilherme Souza Ribeiro,¹ Soraia Machado Corderio,¹ Kátia Salgado,³ Mitermayer Galvão Reis,¹ and Albert I. Ko^1,4*

Centro de Pesquisas Gonçalo Moniz, Fundação Oswaldo Cruz, Ministério da Saúde,¹ Faculdade de Farmácia, Universidade Federal da Bahia,² Hospital Couto Maia, Secretaria da Saúde do Estado da Bahia, Salvador, Brazil,³ Division of International Medicine and Infectious Diseases, Department of Medicine, Weill Medical College of Cornell University, New York, New York 10021⁴

Received 4 June 2002/ Returned for modification 16 July 2002/ Accepted 5 August 2002

Antimicrobial susceptibility was determined for 150 Haemophilus influenzae isolates obtained during population-based surveillance for meningitis in Salvador, Brazil. Ten (6.7%) isolates were resistant to ampicillin and chloramphenicol. Of these, two isolates, a ß-lactamase and non-ß-lactamase producer, were resistant to amoxacillin-clavulinic acid. These findings indicate that present antibiotic regimens in Brazil may not be appropriate for the treatment of H. influenzae meningitis.

* Corresponding author. Mailing address: Centro de Pesquisas Gonçalo Moniz, Fundação Oswaldo Cruz/MS, Rua Waldemar Falcão, 121, Salvador, Bahia 40295-001, Brazil. Phone: (55 71) 356-4320. Fax: (55 71) 356-2155. E-mail: aik2001@med.cornell.edu.

Antimicrobial Agents and Chemotherapy, November 2002, p. 3641-3643, Vol. 46, No. 11
0066-4804/02/$04.00+0     DOI: 10.1128/AAC.46.11.3641-3643.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.




 

Copyright © 2002 by the American Society for Microbiology. All rights reserved.

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