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Mercury in Drug and Biologic Products

FDA/Center for Drug Evaluation and Research
 

The information in this list is derived from submissions made by manufacturers in response to the agency's call-for-data notices of December 14, 1998 (63 FR 68775) and April 29, 1999 (64 FR 23083), the agency's Drug Registration and Listing System, and other agency sources. The mercury ingredients are abbreviated as TM for thimerosal, PMA for phenylmercuric acetate, PMN for phenylmercuric nitrate, MA for mercuric acetate, MN for mercuric nitrate, MB for merbromin, and MOY for mercuric oxide yellow. The list includes nonhomeopathic human and veterinary drug products and human biological products. Homeopathic drug products are not included because of the low amounts of mercury present in the product. The abbreviation NS under the % column means that the information was "not stated" in the agency's Drug Registration and Listing System.

Mercury

Manufacturer	Name of Product	Ingredient	%
Akorn Inc.	AK Spore Ophthalmic Solution	TM	.001
Akorn Inc.	AK Spore HC Ophthalmic Combo Drops	TM	NS
Akorn Inc.	Fluoracaine Ophthalmic Solution	TM	NS
Akorn Inc.	AK Spore HC Otic Suspension	TM	NS
Alcon Laboratories	Profenal 1% Ophthalmic Solution	TM	.005
Alcon Laboratories	Adsorbonac 2% Ophthalmic Solution	TM	.004
Alcon Laboratories	Adsorbonac 5% Ophthalmic Solution	TM	.004
ALK Laboratories Pharmacia	Coccidioidin Vaccine	TM	.01
Allergan Inc.	Blephamide SOP Ophthalmic Ointment	PMA	.0008
Allergan Inc.	Bleph-10 Ophthalmic Ointment 10%	PMA	.0008
Allergan Inc.	FML SOP Ophthalmic Ointment 0.1%	PMA	.0008
Allergan America	Ocufen Ophthalmic Solution	TM	.005
Allergan Inc.	Poly Pred Ophthalmic Suspension	TM	.001
Allergan America	Poly Pred Ophthalmic Suspension	TM	.001
Altaire Pharmaceuticals	Nasal Relief 12 Hour Spray	PMA	NS
American Assn. Retired Persons	Oxymetazoline Nasal Spray	PMA	.002
American International Chemical	Thimerosal (bulk chemical)	TM	100
American International Chemical	Thimerosal (bulk chemical)	TM	100
American International Chemical	Thimerosal USP 97% (bulk chemical)	TM	97
American Pharmaceutical	12 Hour Nasal Solution	PMA	NS
Appletree Markets	Long Lasting Nasal Spray	PMA	NS
B. F. Ascher & Co.	Baby AYR Saline Nose Spray/Drops	TM	.00025
B. F. Ascher & Co.	AYR Saline Nasal Drops	TM	.00025
B. F. Ascher & Co.	AYR Saline Nasal Mist	TM	.00025
Bausch & Lomb	Flurbiprofen Sodium Ophthalmic Solution	TM	.005
Bausch & Lomb	Neomycin & Polymyxin B Sulfates & Gramicidin Ophthalmic Solution	TM	.001
Bausch & Lomb	Neomycin & Polymyxin B Sulfates & Hydrocortisone Otic Suspension	TM	.01
Bausch & Lomb	Sulfacetamide Sodium & Prednisolone Sodium Phosphate Ophthalmic Solution 10%/.23%	TM	.01
Baxter Healthcare Corporation	Immune Globulin Vaccine	TM	.01
Bayer Corporation	Nasal Saline Moisturizer Spray	TM	.001
Bayer Corporation	Neo-Synephrine 12-Hour Nasal Decongestant Spray	PMA	.002
Bayer Corporation	Neo-Synephrine Extra Strength Drops	TM	.001
Bayer Corporation	Neo-Synephrine Mild Formula Spray	TM	.001
Bayer Corporation	Neo-Synephrine Regular Strength Spray	TM	.001
Bayer Corporation	Neo-Synephrine Extra Strength Spray	TM	.001
Bayer Corporation	Neo-Synephrine Regular Strength Drops	TM	.001
Bayer Corporation	Neo-Synephrine 12-Hour Extra Moisturizing Spray	PMA	.002
Berna Products	Tetanus Vaccine Adsorbed	TM	.01
Bioport Corporation	Tetanus Toxoid Adsorbed	TM	.01
Bioport Corporation	Rabies Vaccine Adsorbed	TM	.01
Bioport Corporation	Immune Globulin (Human)	TM	01
Bioport Corporation	Pertussis Vaccine Adsorbed	TM	.01
Bioport Corporation	Diphtheria & Tetanus Toxoids Adsorbed	TM	.01
Bioport Corporation	Diphtheria & Tetanus Toxoids & Pertussis Vaccine Adsorbed	TM	.01
Bristol-Myers Squibb	Fungizone Lotion	TM	.01
Bristol-Myers Squibb	Fungizone Cream	TM	.01
C.O. Truxton Inc.	Bio-Cot Otic Suspension	TM	.01
C.O. Truxton Inc.	Decongest Nasal Spray	PMA	NS
Carlisle Laboratories	Oxymetazoline Nasal Relief Spray	PMA	NS
Carlisle Laboratories	Neomycin Polymyxin B Sulfates Gramicidin Ophthalmic Solution	TM	.01
Carlisle Laboratories	Neomycin Polymyxin B Sulfates Hydrocortisone Otic Suspension	TM	.01
Cheshire Pharmaceutical	Otocort Otic Suspension	TM	.01
Cheshire Pharmaceutical	Ocutricin Ophthalmic Solution	TM	.01
Cheshire Pharmaceutical	Sulfapred Ophthalmic Solution	TM	NS
Clay Park Labs.	PREP Hemorrhoidal Ointment	MN	NS
Clay Park Labs.	Little Noses Saline Spray/Drops	MA	.002
Clay Park Labs	Cheracol Nasal Spray 12 Hour	PMA	.005
Clay Park Labs	PREP-HEM Hemorrhoidal Suppositories	PMN	NS
Clay Park Labs	Long Acting Nasal Spray	PMA	NS
Conair Corp.	Decongestant Nasal Spray	PMA	NS
Connaught Laboratories	Diphtheria & Tetanus Toxoids Adsorbed	TM	.01
Connaught Laboratories	Diphtheria & Tetanus Toxoids & Pertussis Vaccine Adsorbed	TM	.01
Connaught Laboratories	Mumps Skin Test Antigen	TM	.01
Connaught Laboratories	Influenza Virus Vaccine, Trivalent, Types A & B	TM	.01
Connaught Laboratories	Tetanus Toxoid for Booster Use Only	TM	.01
Connaught Laboratories	Influenza Virus Vaccine, Trivalent, Types A & B	TM	.01
Connaught Laboratories	Haemophilus b Conjugate Vaccine Reconstituted with Diphtheria & Tetanus Toxoids & Acellular Pertussis Vaccine Adsorbed	TM	.01
Connaught Laboratories	Tetanus Toxoid Adsorbed	TM	.01
Connaught Laboratories	Diphtheria & Tetanus Toxoids & Acellular Pertussis Vaccine Adsorbed	TM	.01
Connaught Laboratories	Haemophilus b Conjugate Vaccine	TM	.01
Connaught Laboratories	Tetanus and Diphtheria Toxoids Adsorbed	TM	.01
Connaught Laboratories	Japanese Encephalitis Virus Vaccine	TM	.007
Connaught Laboratories	Diluent for Meningococcal Vaccine Groups	TM	0.1
CVS Revco DS Inc.	12 Hour Decongestant Pump Nasal Spray	PMA	NS
CVS	Nasal Spray Pump	PMA	NS
Darby Group Companies	Neomycin Polymyxin B Sulfates Hydrocortisone Otic Suspension	TM	.01
Dolder Ltd.	Thimerosal (bulk chemical)	TM	100
Dorex International Corp.	Long Acting Nasal Spray	PMA	.002
Drug Guild Distributors	Long Acting Decongestant Nasal Spray	PMA	NS
Drug Guild Distributors	Nasal Spray 12 Hour Pump	PMA	NS
Drug Guild Distributors	Long Acting Nasal Spray Kolex LA	PMA	.002
DRX Pharmaceutical	Blephamide Ophthalmic Ointment	PMA	NS
DRX Pharmaceutical	Cortisporin Ophthalmic Suspension	TM	.001
DRX Pharmaceutical	Neomycin Polymyxin B Sulfates Hydrocortisone Ophthalmic Suspension	TM	NS
DRX Pharmaceutical	Neomycin Polymyxin B Hydrocortisone Otic Suspension	TM	.01
DRX Pharmaceutical	Neomycin Polymyxin B Gramicidin Ophthalmic Solution	TM	.01
DRX Pharmaceutical	Vasocidin Ophthalmic Solution	TM	NS
DRX Pharmaceutical	Colymycin S Otic Suspension	TM	.002
DRX Pharmaceutical	Pediotic Otic Suspension	TM	NS
Dysers Sal	Thimerosal (bulk chemical)	TM	NS
Family Independent Pharmacy	12 Hour Nasal Decongestant Spray	PMA	NS
Family Independent Pharmacy	Long Acting Nasal Spray	PMA	NS
Farm Fresh Inc.	Hemorrhoid Relief Ointment	PMN	.01
Fays Drug Services	12 Hour Nasal Spray Pump	PMA	NS
Federated Foods	Long Acting Nasal Spray	PMA	.002
Fleming Companies	12 Hour Nasal Spray	PMA	.002
Foxmeyer Drug Co.	Nasal Spray Pump	PMA	NS
Global Source	Nasin Long Acting Nasal Spray	PMA	NS
Harco Drug	Mercurochrome Aqueous Solution	MB	2
Harris-Teeter	Oxymetazoline Nasal Spray	PMA	.002
Hi Tech Pharmacal Co.	Long Acting Nasal Spray	PMA	.002
Hudson Corp.	Nasal Spray Extended Relief	PMA	NS
Hurst Pharmaceutical	Duomycin-HC Otic Suspension	TM	.01
K and B Distributors	Mercurochrome Aqueous Solution	MB	2
King Pharmaceuticals	Cortisporin Ophthalmic Suspension	TM	.001
King Pharmaceuticals	Neosporin Ophthalmic Suspension	TM	.001
King Pharmaceuticals	Viroptic Ophthalmic Solution	TM	.001
King Pharmaceuticals	Neomycin Polymyxin B Sulfates Hydrocortisone Otic Suspension	TM	NS
King Pharmaceuticals	Pediotic Suspension	TM	.001
King Pharmaceuticals	Cortisporin Otic Suspension	TM	.01
Kinray	Oxymetazoline Nasal Spray	PMA	.002
Laboratori Derivati	Adrenal Cortex Injection	TM	.01
Leader	12 Hour Nasal Spray	PMA	NS
Leader	Nasal Pump Spray	PMA	NS
Longs Drug Stores	Nasal Spray Pump	PMA	NS
LS Raw Materials Ltd.	Mercurochrome NF 12 100% (bulk chemical)	MB	100
Major Pharmaceuticals	Cortomycin Ophthalmic Suspension	TM	NS
Major Pharmaceuticals	Sulfacetamide Sodium & Prednisolone Sodium Phosphate Ophthalmic Solution	TM	.01
Major Pharmaceuticals	Cortomycin Otic Suspension	TM	.01
Major Pharmaceuticals	Neocidin Ophthalmic Solution	TM	.01
Martin Surgical Supply	Testosterone Injection Suspension 50 mg	TM	.008
Martin Surgical Supply	Testosterone Injection Suspension 100 mg	TM	NS
Massachusetts Public Health Biologic Labs	Tetanus and Diphtheria Toxoids Adsorbed For Adult Use	TM	.003
Massachusetts Public Health Biologic Labs	Diphtheria and Tetanus Toxoids Adsorbed	TM	.01
Mays Drug Stores	Hemorrhoid Relief Ointment	PMN	.01
Medalist Laboratories	Long Lasting Nasal Spray Pump	PMA	NS
Medeva Pharmaceuticals	Influenza Virus Vaccine	TM	.01
Merck & Co.	Hepatitis B Vaccine, recombinant	TM	.005
Merck & Co.	Antivenin (Lactrodectus Mactans)	TM	.01
Meyers Supply Inc.	Long Acting Nasal Spray	PMA	.002
Naska Pharmacal Co.	Hemorrhoid Relief Ointment	PMN	.01
Navresso	Long Acting Nasal Spray	PMA	NS
North American Vaccine	Diphtheria & Tetanus Toxoids & Pertussis Adsorbed	TM	.01
Omicron Quimica SA	Thimerosal USP 97% (bulk chemical)	TM	97
Ortho-Clinical Diagnostics	Rho (D) Immune Globulin (Human)	TM	.003
Ortho-Clinical Diagnostics	Rho (D) Immune Globulin (Human)	TM	.003
Parade (Grocer's Supply)	Oxymetazoline Nasal Spray	PMA	.002
Parke Davis	Elase-Chloromycetin Topical Ointment	TM	NS
Parkedale Pharmaceuticals	Coly-Mycin S Otic Suspension	TM	.002
Parkedale Pharmaceuticals	Influenza Virus Vaccine, Trivalent, Types A & B	TM	.01
Pay N Save Corp.	Decongestant Nasal Spray	PMA	NS
Pharmacia & Upjohn	Anti-Thymocyte Immune Globulin, Human	TM	.01
Pharmacia & Upjohn	Allergen Patch Test	TM
Pharmedix	Bleph 10 Ophthalmic Solution 10%	TM	.005
Pharmedix	Viroptic Ophthalmic Solution 1%	TM	.001
Pharmedix	Blephamide Ophthalmic Ointment	PMA	NS
Pharmedix	Triple Antibiotic Ophthalmic Solution	TM	.01
Pharmedix	Colymycin S Otic Solution	TM	.002
Pharmedix	Neo Poly with HC Otic Suspension	TM	.01
Physicians Total Care	NeoSynephrine Nasal Spray 0.25%	TM	NS
Physicians Total Care Inc.	Neomycin Polymyxin B Sulfates Hydrocortisone Ophthalmic Suspension	TM	NS
Physicians Total Care Inc.	Viroptic Ophthalmic Solution	TM	.001
Physicians Total Care Inc.	Cortisporin Ophthalmic Suspension	TM	.001
Physicians Total Care Inc.	Ocufen Ophthalmic Solution	TM	.0005
Physicians Total Care Inc.	Vasocidin Ophthalmic Solution	TM	NS
Ping On Ointment Co. Ltd.	Ping On Topical Ointment	Mercury	NS
Prime Natural Health	12 Hour Nasal Spray	PMA	NS
Primedics Laboratories	Testerone Injection Suspension 50 mg	TM	.008
Publix Supermarkets	Long Acting Decongestant Nasal Spray	PMA	NS
Publix Inc.	Long Acting Nasal Spray	PMA	NS
Qualitest Pharmaceuticals	Nasal Spray Solution	PMA	NS
Qualitest Pharmaceuticals	Antibiotic HC Otic Suspension	TM	NS
RDS Acquisition Corp.	12 Hour Nasal Spray	PMA	NS
Republic Drug Co.	12 Hour Nasal Spray	PMA	.002
Rugby Laboratories	Nasal Relief Spray Long Acting	PMA	.002
Schein Pharmaceutical	Neomycin Polymyxin B Sulfates Hydrocortisone Ophthalmic Suspension	TM	NS
Schein Pharmaceutical	Sulfacetamide Sodium & Prednisolone Sodium Phosphate Ophthalmic Solution	TM	NS
Schein Pharmaceutical	Testosterone Injection Suspension 100 mg	TM	NS
Schein Pharmaceutical	Neomycin Polymyxin B Sulfates Hydrocortisone Otic Suspension	TM	.01
Schein Pharmaceutical	Trifluridine Ophthalmic Solution	TM	NS
Schein Pharmaceutical	Oxymetazoline HC1 Nasal Spray	PMA	NS
Schein Pharmaceutical	Phenylephrine HC1 Nasal Solution 1%	TM	NS
Schering-Plough Animal Health	Gentocin Durafilm Ophthalmic Solution (for dogs only)	PMN	.002
Scrivner, Inc.	Hemorrhoid Relief Ointment	PMN	.01
Sight Pharmaceuticals	Neomycin Polymyxin B Sulfates Hydrocortisone Otic Suspension	TM	NS
Sight Pharmaceuticals	Sulfacetamide Sodium & Prednisolone Sodium Phosphate Ophthalmic Solution	TM	.01
SmithKline Beecham	Hepatitis B Vaccine, recombinant	TM	.005
Spectrum Quality Products	Merbromin (bulk chemical)	MB	100
Spectrum Quality Products	Mercuric Oxide Yellow (bulk chemical)	MOY	100
Spectrum Quality Products	Thimerosal (bulk chemical)	TM	100
Spectrum Quality Products	Thimerosal (bulk chemical)	TM	100
Super Laboratories	Long Acting Nasal Spray	PMA	NS
Super D Drugs	Long Acting Nasal Spray	PMA	NS
Taro Pharmaceuticals	Taro Nasal Decongestant Spray	PMA	.002
Teral Laboratories	Oticin HC Otic Suspension	TM	.01
Thames Pharmacal Co.	12 Hour Nasal Spray	PMA	NS
Thrift Drugs	Long Acting Nasal Spray	PMA	NS
Thrifty Payless Inc.	Nasal Spray Pump Formula	PMA	NS
Thrifty Payless Inc.	Decongestant Nasal Spray Pump	PMA	NS
United Research Labs	Antibiotic Ear Suspension	TM	.01
United Research Labs	Neomycin Polymyxin B Sulfates Gramicidin Ophthalmic Solution	TM	.01
US Ophthalmics	Fluorescein Sodium Ophthalmic Solution	TM	NS
US Ophthalmics	Sulf-10 Ophthalmic Solution	TM	NS
US Ophthalmics	Vasocidin Ophthalmic Solution	TM	NS
US Ophthalmics	Phenylephrine HC1 Ophthalmic Solution 10%	TM	NS
USCO Logistics	Procofen Ophthalmic Solution	TM	.005
USCO Logistics	Profenal Ophthalmic Solution	TM	.005
VEDCO Inc.	Tribiotic Ophthalmic Solution	TM	NS
Waldbaum Inc.	Hemorrhoidal Ointment	MN	NS
Weeks and Leo Co. Inc.	Long Acting Nasal Spray Solution	PMA	.002
Whilehall-Robins	Dristan 12-Hour Nasal Spray	TM	.002
Wyeth Laboratories	Antivenin (Micrurus Fulvius)	TM	.005
Wyeth Laboratories	Normal Horse Serum (1:10 dilution)	TM	.005
Wyeth Laboratories	Influenza Virus Vaccine, Trivalent, Types A & B	TM	.01
Wyeth Laboratories	Diphtheria and Tetanus Toxoids Adsorbed	TM	.01
Wyeth Laboratories	Antivenin (crotalidae) Polyvalent	TM	.005
Wyeth Laboratories	Tetanus and Diphtheria Toxoids Adsorbed	TM	.01
Wyeth Laboratories	Tetanus Toxoid, fluid	TM	.01
Wyeth Laboratories	Tetanus Toxoid Adsorbed	TM	.01
Wyeth Laboratories	Wydase Lyophilized Solution	TM	.01
Wyeth Laboratories	Wydase Solution Stabilized	TM	.01
Wyeth Laboratories	Bacteriostatic Water for Injection	PMN	.001
Wyeth-Lederle Vaccines	Diphtheria and Tetanus Toxoids & Acellular Pertussis Vaccine Adsorbed	TM	.01
Wyeth-Lederle Vaccines	Pneumococcal Vaccine, Polyvalent	TM	.01
Wyeth-Lederle Vaccines	Diphtheria and Tetanus Toxoids & Pertussis Vaccine Adsorbed & Haemophilus b Conjugate Vaccine	TM	.01
Wyeth-Lederle Vaccines	Tetanus Toxoid Adsorbed	TM	.01
Wyeth-Lederle Vaccines	Tetanus and Diphtheria Toxoids Adsorbed	TM	.01
Wyeth-Lederle Vaccines	Diphtheria and Tetanus Toxoids Adsorbed	TM	.01
Wyeth-Lederle Vaccines	Haemophilus b Conjugate Vaccine	TM	.01

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Last modified: October 17, 2007

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ALL INFORMATION, DATA, AND MATERIAL CONTAINED, PRESENTED, OR PROVIDED HERE IS FOR GENERAL INFORMATION PURPOSES ONLY AND IS NOT TO BE CONSTRUED AS REFLECTING THE KNOWLEDGE OR OPINIONS OF THE PUBLISHER, AND IS NOT TO BE CONSTRUED OR INTENDED AS PROVIDING MEDICAL OR LEGAL ADVICE.  THE DECISION WHETHER OR NOT TO VACCINATE IS AN IMPORTANT AND COMPLEX ISSUE AND SHOULD BE MADE BY YOU, AND YOU ALONE, IN CONSULTATION WITH YOUR HEALTH CARE PROVIDER.