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Reported November 2001 Click here to send this page to a friend!

Vaccines of the Future

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NEW ORLEANS (Ivanhoe Newswire) — Scientists in previous years have developed ways to stop diseases like tetanus and measles and are working quickly to develop more widely available ones against biological weapons such as anthrax and smallpox. However, what about diseases that afflict millions today? Last year, 3 million people worldwide died from AIDS. Another 4 million Americans are living with Alzheimer's disease. Here's an answer that may be closer than you think.

Kenneth Jestings says, "I lost 65 friends in the course of one year."

Jestings is considered by researchers as high risk for AIDS. He and 8,000 others are in a study to test a vaccine that may one day save millions of lives.

"We know that people who get the vaccine will develop antibodies. We know that it's safe. But we don't know if it will work in real life human situations," says infectious disease specialist Richard DiCarlo, M.D., of the Louisiana State University Medical Center.

The goal of AIDSVax is to prevent the virus from infecting healthy cells. Results will not be known for a few years, but researchers and volunteers are hopeful.

Jestings says, "Maybe this next go around we won't lose anybody at all if this vaccine works."

Tampa, Fla. resident Cristina Vera says, "It would be a wonderful thing if they could come up with something that would help this because it's such a devastating disease."

Vera worries not about AIDS, but about Alzheimer's disease. She says it has destroyed her mother. A vaccine under development may keep other families from suffering like Vera's. These mice are modified to develop Alzheimer's-causing plaque in their brains and are put through this maze to test their memories. With the vaccine, they show no signs of memory loss.

"It apparently triggers the immune system to remove that material like it would bacteria and an infection," says researcher Dave Morgan, Ph.D., of the University of South Florida in Tampa.

Other vaccines under development are for diabetes and addictions. Early studies are also underway for hepatitis c and h-pylori, the bacteria thought to cause ulcers.

Clinical researcher Robert Edelman, M.D., says with new delivery methods to improve the vaccines we have, and research into new ones, scientists are gaining the upper hand on diseases.

"That's the 21st century. A whole new area for the improvement of the welfare of mankind," says Dr. Edelman, of the University of Maryland Medical Center in Baltimore.

Dr. Edelman also says delivery methods such as nasal drops may prove to be more effective because they enter the body the same way as does the virus they are fighting. Other methods under development include edible vaccines and skin patches.

If you would like more information, please contact:

VaxGen Inc.

1000 Marina Blvd., Suite 200

Brisbane, CA 94005

(650) 624-1000

If you would like more information on Alzheimer's research, please contact:

David Morgan, Ph.D.

Dept. of Pharmacology

University of South Florida

12901 Bruce B. Downs Blvd.

Tampa, FL 33612-4799

(813) 974-3949

Related Articles:
AIDS Breakthrough (July 2001)
Preventing Diabetes (May 2001)
Brain Tumor Vaccine (April 2001)
Alzheimer's Vaccine (March 2001)
Stopping the Return of Skin Cancer (February 2001)
Preventing Ear Infections (January 2001)
HIV-Free Infants (January 2001)
Cancer Vaccine (July 2000)
Kidney Cancer Vaccine (September 1999)

 

ALL INFORMATION, DATA, AND MATERIAL CONTAINED, PRESENTED, OR PROVIDED HERE IS FOR GENERAL INFORMATION PURPOSES ONLY AND IS NOT TO BE CONSTRUED AS REFLECTING THE KNOWLEDGE OR OPINIONS OF THE PUBLISHER, AND IS NOT TO BE CONSTRUED OR INTENDED AS PROVIDING MEDICAL OR LEGAL ADVICE.  THE DECISION WHETHER OR NOT TO VACCINATE IS AN IMPORTANT AND COMPLEX ISSUE AND SHOULD BE MADE BY YOU, AND YOU ALONE, IN CONSULTATION WITH YOUR HEALTH CARE PROVIDER.