http://www.nytimes.com/aponline/national/AP-Smallpox.html
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November 9, 2001 Old Smallpox Vaccines May Still Help
By THE ASSOCIATED PRESS
Filed at 5:12 p.m. ET ATLANTA (AP) -- With the anthrax scare stirring fears of a far deadlier
smallpox attack, health officials are trying to reassure the public that
people vaccinated decades ago are probably still protected. The government has 15.4 million doses of smallpox vaccine and wants to buy
300 million more, enough to vaccinate the entire country. However, there are
no government plans for a mass vaccination. Health experts say the immune systems of people who received multiple
shots before the government ended smallpox vaccinations in 1972 can probably
still fight the disease. Before the program ended, children were immunized as toddlers and usually
again when they started school. And international travelers were required to
show proof of a recent vaccination. ``If someone has had three immunizations, it would offer a significant
degree of protection for decades,'' said Dr. Harry L. Keyserling, a smallpox
expert at Emory University. Research on smallpox outbreaks from the early 1900s shows the disease
killed only 10 percent of people who had been vaccinated as much as 50 years
before. The Centers for Disease Control and Prevention's bioterrorism Web site
says the level of immunity left in people vaccinated before 1972 is
uncertain. And the CDC conservatively warns the vaccine is most effective for
three to five years. But the agency is revising its guidelines to let state health departments
know about the vaccine's lingering protection, said Dr. James LeDuc, acting
head of the agency's viral division. The government opposes mass vaccinations because it believes they are
unnecessary and because the vaccine can cause crippling side effects. Smallpox was declared eradicated worldwide in 1980, but the virus is
stored in government laboratories in a few places around the world. The virus is contagious and deadly, killing three in 10 of its victims.
But experts say that a smallpox attack is unlikely to unleash a doomsday
outbreak that could instantly get out of control. There is a window of up to 11 days between the time people contract the
virus and the time they actually become sick and develop the scabs that make
the disease contagious. Particularly in a time of heightened alert, doctors say they would
probably be able to recognize a small outbreak during that window and quickly
vaccinate people who came in contact with the victims. ``It has a rather slow evolution,'' LeDuc said. ``We think it's not going
to be a wildfire.'' Smallpox is among the bioterrorism agents the CDC has warned doctors to
watch for since the Sept. 11 attacks. No case has been documented in the
United States since 1949. Health officials have never stopped testing the effectiveness of the U.S.
stockpile of vaccine and said they are confident it would work. ``The stuff is incredibly stable,'' LeDuc said. ^------ On the Net: CDC bioterrorism site: ALL
INFORMATION, DATA, AND MATERIAL CONTAINED, PRESENTED, OR PROVIDED HERE IS FOR
GENERAL INFORMATION PURPOSES ONLY AND IS NOT TO BE CONSTRUED AS REFLECTING
THE KNOWLEDGE OR OPINIONS OF THE PUBLISHER, AND IS NOT TO BE CONSTRUED OR
INTENDED AS PROVIDING MEDICAL OR LEGAL ADVICE. THE DECISION WHETHER OR
NOT TO VACCINATE IS AN IMPORTANT AND COMPLEX ISSUE AND SHOULD BE MADE BY YOU,
AND YOU ALONE, IN CONSULTATION WITH YOUR HEALTH CARE PROVIDER. |
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