Illness after influenza vaccination reported through a nationwide surveillance system, 1976-1977.

http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7361749&form=6&db=m&Dopt=b

: Am J Epidemiol 1980 Mar;111(3):270-8

Illness after influenza vaccination reported through a nationwide surveillance system, 1976-1977.

Retailliau HF, Curtis AC, Storr G, Caesar G, Eddins DL, Hattwick MA.

In 1976, the Center for Disease Control coordinated nationwide surveillance for illnesses after influenza vaccination as part of an effort to vaccinate the nation against influenza A/New Jersey/76. For the 48,161,019 persons vaccinated in 1976, a total of 4733 reports of illness were received which included reports of 223 deaths. When Guillain-Barre syndrome was reported in vaccine recipients, an investigation was begun to examine this possible association. Other than the Guillain-Barre syndrome and rare cases of anaphylaxis, no serious illnesses were causally associated with influenza vaccination by this type of surveillance. Widespread underreporting of illness and death in the passive phase of this surveillance system, however, impaired the ability to draw conclusions about reactions to vaccine from the reports of illness received.

PMID: 7361749 [PubMed - indexed for MEDLINE]

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