"Modelling Cost Effectiveness of Meningococcal Serogroup C Conjugate Vaccination Campaign in England and Wales"
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"Modelling Cost Effectiveness of Meningococcal
Serogroup C Conjugate Vaccination Campaign in England and Wales" British Medical
Journal Online (www.bmj.com)
(04/06/02) Vol. 324, No. 7341, P. 809; Trotter, Caroline L.; Edmunds, John
Before the introduction of the meningococcal C
vaccination in England
and Wales, the disease caused roughly 1,137 cases in people under the age of 18
years between 1998 and 1999, resulting in at least 72 deaths. Because the
ensuing vaccination campaign cost between 126 million pounds and 241 million
pounds, researchers strove to determine the cost-effectiveness of the campaign
in terms of cost per life year saved. Overall, each life year saved cost 6,259
pounds, though school-based vaccinations were more effective and cost less.
Vaccination of children younger than one year was effective in terms of life
years saved, but was the most costly because of the course of three doses needed
for each child. As meningococcal serogroup C disease is most prevalent in those
under the age of 18 years, the vaccination campaign was found to be
cost-effective, though it was most cost-effective when administered to children
between the ages of one year and four years by doctors and between the ages of
five years and 17 years at a school setting.
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