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MEDSCAPE's Pediatrics MedPulse(R)
medscape.com/pediatricshome
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MedPulse is a weekly index of key news and features on Medscape's
specialty sites compiled by Medscape's Editors.
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___________________ NEW FEATURE ARTICLES THIS WEEK ____________________

INTERNATIONAL SOCIETY FOR HEART AND LUNG TRANSPLANTATION 22ND ANNUAL MEETING AND SCIENTIFIC SESSIONS
Treatment protocols and clinical strategies for enhanced care of thoracic transplant recipients: Highlights from the ISHLT 2002
Medscape Transplantation 2002
medscape.com/viewprogram/1825?srcmp=ped-050302

PREVENTION OF PNEUMOCOCCAL DISEASE IN CHILDREN
Pneumococcal disease in the young -- what can we do to stop Streptococcus pneumoniae infection?
Medscape Pediatrics 2002
medscape.com/viewprogram/1807?srcmp=ped-050302

MEDIUM AND LONG-TERM GROWTH IN CHILDREN RECEIVING INTRANASAL BECLOMETHASONE DIPROPIONATE: A CLINICAL EXPERIENCE
Should clinicians use a stadiometer to record measurements of growth for all children who receive corticosteroids?
South Med J 95(3) 2002
medscape.com/viewarticle/431605?srcmp=ped-050302

KETOROLAC FOR PAIN MANAGEMENT AFTER ABDOMINAL SURGICAL PROCEDURES IN INFANTS
Could a simple NSAID be used to prevent undesirable opioid effects on respiratory, cardiovascular, and CNS function?
South Med J 95(3) 2002
medscape.com/viewarticle/431604?srcmp=ped-050302


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ROLE OF CORPECTOMY FOR MANAGING CERVICAL SPONDYLOSIS
Surgical advances have expanded the role of corpectomy for managing
cervical spondylosis. Review indications, techniques, complications,
and outcomes in "Role of Corpectomy in Cervical Spondylosis," available
in the Spine Surgery area of the Medscape Spine Disorders Resource Center
at medscape.com/mp/rc/spine


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___________________________________ NEWS ______________________________


--Behavioral and Learning Disorders--
MATERNAL DEPRESSION MAY AFFECT INFANT LEARNING
Stimulation of young infants with 'baby talk' helps foster learning.
Reuters Health Information 2002
medscape.com/viewarticle/432971?srcmp=ped-050302

INTENSIVE READING PROGRAM MAY ALTER BRAIN ACTIVITY IN DYSLEXIA
In a finding that raises hopes about the effective treatment of dyslexia, the results of a small study show that intensive reading instruction may reverse the abnormal brain activity that occurs in children with the learning disability.
Reuters Health Information 2002
medscape.com/viewarticle/432855?srcmp=ped-050302

METHYLPHENIDATE FORMULATION CAN BE MIXED WITH FOOD WITHOUT ALTERING DRUG LEVELS
Removing an extended-release formulation of methylphenidate from its capsule and sprinkling it on food does not alter the drug's bioavailability
Reuters Health Information 2002
medscape.com/viewarticle/432783?srcmp=ped-050302

REGRESSIVE AUTISM MAY BE LINKED TO AUTOIMMUNE ENTEROPATHY
A regressive type of autism may have an autoimmune basis, either directly or indirectly from an autoimmune enteropathy.
MedscapeWire 2002
medscape.com/viewarticle/432692?srcmp=ped-050302


--Cardiovascular Disorders--
SILDENAFIL MAY BE POTENTIAL THERAPY FOR PULMONARY HYPERTENSION IN NEWBORNS
New animal research suggests that sildenafil could help treat persistent pulmonary hypertension of the newborn.
Reuters Health Information 2002
medscape.com/viewarticle/432755?srcmp=ped-050302


--Fetal Anomalies and Birth Defects--
LORATIDINE LINKED TO BIRTH DEFECTS IN EUROPE
The European Medicines Evaluation Agency (EMEA) announced a safety review of Schering-Plough's hayfever drug loratidine (Clarityn) after reports of an unusually high number of birth defects in children born to mothers who used the drug while pregnant.
Reuters Health Information 2002
medscape.com/viewarticle/432654?srcmp=ped-050302

MINOR BIRTH COMPLICATIONS UNLIKELY TO AFFECT DEVELOPMENT OF AUTISM
An increased rate of minor birth and pregnancy complications appears to accompany familial factors associated with autism.
Reuters Health Information 2002
medscape.com/viewarticle/432711?srcmp=ped-050302


--Gastrointestinal Disorders--
ONDANSETRON REDUCES VOMITING IN PEDIATRIC GASTROENTERITIS
Ondansetron is safe and effective in reducing the vomiting associated with acute gastroenteritis, according to the results of a randomized trial.
MedscapeWire 2002
medscape.com/viewarticle/432689?srcmp=ped-050302

HEPATITIS B VACCINE UPTAKE IN NEONATES LINKED TO GESTATIONAL AGE
Seroconversion rates following hepatitis B vaccination in neonates is linked with gestational age, with rates significantly lower in preterm infants.
Reuters Health Information 2002
medscape.com/viewarticle/432776?srcmp=ped-050302

TACROLIMUS SEEMS TO CURB CHRONIC REJECTION IN PEDIATRIC LIVER TRANSPLANTS
The results of a long-term study of 166 pediatric liver transplant recipients who received tacrolimus show that cases of chronic rejection are rare.
Reuters Health Information 2002
medscape.com/viewarticle/432854?srcmp=ped-050302


--HIV/AIDS--
PROTEASE INHIBITORS CROSS PLACENTAL BARRIER TO LIMITED EXTENT
In contrast to nevirapine, which readily crosses the placental barrier, protease inhibitors, such as nelfinavir and ritonavir, demonstrate limited transplacental passage.
Reuters Health Information 2002
medscape.com/viewarticle/432680?srcmp=ped-050302

MUTATIONS REDUCE STAVUDINE SUSCEPTIBILITY IN HIV-POSITIVE CHILDREN
Researchers have found that although the effect of stavudine-resistant mutations in HIV-positive children is small, these mutations, which are similar to those found for zidovudine, are clinically significant.
Reuters Health Information 2002
medscape.com/viewarticle/432721?srcmp=ped-050302


--Respiratory Disorders
S-NITROSOGLUTATHIONE IMPROVES OXYGENATION IN PATIENTS WITH CF
Replacement of airway levels of S-nitrosoglutathione in patients with cystic fibrosis (CF) is well tolerated and leads to modest improvement in gas exchange.
Reuters Health Information 2002
medscape.com/viewarticle/432733?srcmp=ped-050302

BRONCHIOLITIS IN INFANTS NOT IMPROVED BY INHALED ADRENALINE
Contrary to previous findings, results of a British study suggest that inhaled adrenaline is of little value in managing infants with bronchiolitis.
Reuters Health Information 2002
medscape.com/viewarticle/432724?srcmp=ped-050302


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