Vaccination News Home Page

http://www.medscape.com/infectiousdiseaseshome

Click for FREE CME: http://www.medscape.com/mp/cmectr/infectiousdiseases

VACCINES FOR VIRAL HEMORRHAGIC FEVERS: FILOVIRUSES AND ARENAVIRUSES The VHFs are among the most feared, least understood, and most deadly viruses in the world. Medscape Infectious Diseases 4(1) 2002 http://www.medscape.com/viewarticle/433535?srcmp=id-052402

3RD INTERNATIONAL WORKSHOP ON CLINICAL PHARMACOLOGY OF HIV THERAPY John G. Gerber, MD, presents a critical review of new data on PI boosting, pharmacokinetics, pharmacogenomics, and TDM. Medscape HIV/AIDS eJournal 8(1) 2002 http://www.medscape.com/viewarticle/433477?srcmp=id-052402

A review of selected articles from the allergy and clinical immunology literature Medscape Allergy & Clinical Immunology 2(1) 2002 http://www.medscape.com/viewarticle/433665?srcmp=id-052402

POTENTIAL SHORTAGE OF SUPPLEMENTAL TEST KITS FOR DETECTING HIV-1 ANTIBODIES Calypte might stop manufacturing the Cambridge Biotech HIV-1 Western blot kit, one of two licensced supplemental tests. MMWR 51(18) 2002 http://www.medscape.com/viewarticle/433435?srcmp=id-052402

NASOPHARYNGEAL CARRIAGE OF S PNEUMONIAE IN HEALTHY CHILDREN: IMPLICATIONS FOR THE USE OF HEPTAVALENT PNEUMOCOCCAL CONJUGATE VACCINE Most isolated strains are covered by the heptavalent conjugate vaccine, especially in the first years of life. Emerg Infect Dis 8(5) 2002 http://www.medscape.com/viewarticle/432528?srcmp=id-052402

These results support development of a comprehensive conjugate vaccine that would include serogroup X polysaccharide. Emerg Infect Dis 8(5) 2002 http://www.medscape.com/viewarticle/432522?srcmp=id-052402

GENETIC AND ANTIGENIC ANALYSIS OF THE FIRST A/NEW CALEDONIA/20/99-LIKE H1N1 INFLUENZA ISOLATES REPORTED IN THE AMERICAS WHO has recommended including this strain in the vaccine for both the southern and northern hemispheres. Emerg Infect Dis 8(4) 2002 http://www.medscape.com/viewarticle/432415?srcmp=id-052402

LABORATORY REPORTING OF S AUREUS WITH REDUCED SUSCEPTIBILITY TO VANCOMYCIN IN US VETERANS AFFAIRS FACILITIES Between the two survey periods the reported cases of SARV increased 170%. Emerg Infect Dis 8(4) 2002 http://www.medscape.com/viewarticle/432414?srcmp=id-052402

INTRODUCTION OF WEST NILE VIRUS IN THE MIDDLE EAST BY MIGRATING WHITE STORKS The storks were probably infected with WNV at some point along their route of migration in Europe. Emerg Infect Dis 8(4) 2002 http://www.medscape.com/viewarticle/432144?srcmp=id-052402

At least one species is migratory and might be responsible for dissemination around the Mediterranean. Emerg Infect Dis 8(4) 2002 http://www.medscape.com/viewarticle/432416?srcmp=id-052402

EMERGENCE AND RAPID SPREADING OF TETRACYCLINE RESISTANT VIBRIO CHOLERAE STRAINS, MADAGASCAR The Indian Ocean was free of cholera for decades, until January 1998, when an outbreak was detected in Comoros Islands. Emerg Infect Dis 8(3) 2002 http://www.medscape.com/viewarticle/432077?srcmp=id-052402

Comparing computer viruses with their biological counterparts can help us control both. Emerg Infect Dis 8(3) 2002 http://www.medscape.com/viewarticle/432076?srcmp=id-052402

Combination vaccines with an Hib conjugate offer continued protection to infants and young children. Infect Med 19(4) 2002 http://www.medscape.com/viewarticle/433131?srcmp=id-052402

A 53-year-old man with a 45 pack-year history of smoking presented with worsening dyspnea, fever, and cough. Infect Med 19(4) 2002 http://www.medscape.com/viewarticle/433132?srcmp=id-052402

This year's meeting covered developments in fusion inhibitors, clinical debuts of 2 second-generation NNRTIs, and more. Infect Med 19(4) 2002 http://www.medscape.com/viewarticle/433134?srcmp=id-052402

EVALUATION OF SURVIVAL AND PHARMACODYNAMIC RELATIONSHIPS FOR FIVE FLUOROQUINOLONES IN A NEUTROPENIC MURINE MODEL OF PNEUMOCOCCAL LUNG INFECTION The antistreptococcal activity of 5 fluoroqunolones is compared. Pharmacotherapy 22(4) 2002 http://www.medscape.com/viewarticle/432393?srcmp=id-052402

http://www.medscape.com/mp/rc/usmd/sepsis

Some 1200 World Bank employees were advised to stay home from work on Tuesday after inconclusive tests detected anthrax contamination on mail bound for their building, a World Bank spokeswoman said on Monday. Reuters Health Information 2002 http://www.medscape.com/viewarticle/433940?srcmp=id-052402

The US House of Representatives on Wednesday overwhelmingly approved a bill to boost funding for bioterrorism preparedness by $4.6 billion and to renew for 5 more years the law under which prescription drugmakers pay 'user fees' to the Food and Drug Administration to speed the drug review process. Reuters Health Information 2002 http://www.medscape.com/viewarticle/434039?srcmp=id-052402

The US Senate on Thursday unanimously approved a bill designed to expand the nation's bioterrorism preparedness that also includes an unrelated measure renewing the Prescription Drug User Fee Act (PDUFA) for five years. Reuters Health Information 2002 http://www.medscape.com/viewarticle/434097?srcmp=id-052402

NONPROFIT GROUP PETITIONS FDA FOR NEW NEEDLESTICK SAFETY ADVISORY The National Alliance for the Primary Prevention of Sharps Injuries, a non-profit group founded by catheter safety devices maker Venetec International, said on Wednesday that it has petitioned the US FDA to issue a new clinician advisory on needlestick injury prevention. Reuters Health Information 2002 http://www.medscape.com/viewarticle/434031?srcmp=id-052402

CHRONIC HCV INFECTION DOES NOT AFFECT SURVIVAL AFTER KIDNEY TRANSPLANTATION Patients infected with hepatitis C virus prior to kidney transplantation are not at risk for increased mortality following the procedure, according to a report in the April issue of Clinical Transplantation. Reuters Health Information 2002 http://www.medscape.com/viewarticle/434111?srcmp=id-052402

Randomized trials support its use alone and in combination. MedscapeWire 2002 http://www.medscape.com/viewarticle/433755?srcmp=id-052402

HCV-3 IDENTIFIED AS RISK FACTOR FOR LIVER ENZYME ELEVATION AFTER HAART In patients coinfected with HIV and hepatitis C virus, HCV genotype 3 is an independent risk factor for highly elevated transaminase following highly active antiretroviral therapy, according to a recent report. Reuters Health Information 2002 http://www.medscape.com/viewarticle/433970?srcmp=id-052402

CIPROFLOXACIN RESISTANCE SHOWS 'ALARMING' CLIMB IN CALIFORNIA Resistance to the antibiotic ciprofloxacin has shown an 'alarming' increase among patients at one of the western US's largest rehabilitation facilities, a study released here on Monday shows. Reuters Health Information 2002 http://www.medscape.com/viewarticle/433892?srcmp=id-052402

Britain's Public Health Laboratory Service on Friday reported the first case in England involving a new strain of methicillin-resistant Staphylococcus aureus. Reuters Health Information 2002 http://www.medscape.com/viewarticle/433794?srcmp=id-052402

Reuters Health Information 2002 http://www.medscape.com/viewarticle/434100?srcmp=id-052402

The number of British children who received the controversial measles, mumps, and rubella vaccine dropped over the winter, but rates are picking up again, public health officials said on Thursday. Reuters Health Information 2002 http://www.medscape.com/viewarticle/433705?srcmp=id-052402

Wyeth Vaccines, a division of Wyeth, has been awarded a grant by the National Institutes of Health to research a vaccine already shown to prevent an AIDS-like disease in monkeys and may prove to be a useful HIV vaccine, the US research institute said on Friday. Reuters Health Information 2002 http://www.medscape.com/viewarticle/433823?srcmp=id-052402

MILD TO MODERATE PID RESPONDS TO OUTPATIENT ANTIBIOTICS Fertility and other outcomes are comparable to those for hospitalized patients. MedscapeWire 2002 http://www.medscape.com/viewarticle/433700?srcmp=id-052402

CRACK COCAINE USE LINKED TO HIV AND STD EPIDEMICS IN THE BAHAMAS Increased crack cocaine use is associated with heterosexual HIV infection, genital ulcer-inguinal adenopathy disease, and lymphogranuloma venereum, according to two studies conducted in the Bahamas. Reuters Health Information 2002 http://www.medscape.com/viewarticle/434044?srcmp=id-052402

Dutch researchers report the case of a man who developed Creutzfeldt-Jakob disease 38 years after receiving a low-dose of human derived growth hormone during a diagnostic procedure. Reuters Health Information 2002 http://www.medscape.com/viewarticle/434053?srcmp=id-052402

New research from an animal model provides clues to why necrotizing fasciitis infections tend to occur in the winter months. Reuters Health Information 2002 http://www.medscape.com/viewarticle/433959?srcmp=id-052402

MOSQUITOES CAN BE GENETICALLY MODIFIED TO RESIST PLASMODIUM Investigators have successfully generated populations of transgenic Anopheles stephensi mosquitoes that have a greatly diminished potential for carrying and transmitting the malaria parasite. Reuters Health Information 2002 http://www.medscape.com/viewarticle/434037?srcmp=id-052402

Up to 25% fewer Brazilians contracted HIV last year than in 2000, a sign that a controversial program involving condom and needle distribution is working, the government said on Monday. Reuters Health Information 2002 http://www.medscape.com/viewarticle/433976?srcmp=id-052402

S. AFRICAN PATIENTS WITH OCULAR SURFACE SQUAMOUS NEOPLASIA OFTEN HIV POSITIVE Results from a recent study suggest that South Africans who develop ocular surface squamous neoplasia are often HIV positive. Reuters Health Information 2002 http://www.medscape.com/viewarticle/433911?srcmp=id-052402

German drug maker Boehringer Ingelheim gave the Kenyan government on Thursday the first batch of a million doses of a drug to fight HIV/AIDS, officials said. Reuters Health Information 2002 http://www.medscape.com/viewarticle/434092?srcmp=id-052402

Reuters Health Information 2002 http://www.medscape.com/viewarticle/434121?srcmp=id-052402

OREGON FREEZES NEW HIV/AIDS ENROLLMENT IN DRUG AND HEALTH PROGRAM Oregon public health officials have temporarily halted new enrollment in CareAssist, a state medical care and prescription drug assistance program for people with HIV and AIDS. Reuters Health Information 2002 http://www.medscape.com/viewarticle/433894?srcmp=id-052402

HIV-1 PHENOTYPE LINKED TO MOTHER-TO-CHILD HIV-1 TRANSMISSION The presence of the nonsyncytium-inducing (NSI) HIV-1 phenotype and a high viral load significantly increase the risk of mother-to-child transmission of HIV-1, according to the results of a case-control study. Reuters Health Information 2002 http://www.medscape.com/viewarticle/433885?srcmp=id-052402

Unstimulated CD8+ T cells from individuals who have been repeatedly exposed to HIV-1 but remain uninfected can inhibit HIV-1 infection in vitro, according to a report in the May 3rd issue of AIDS. Reuters Health Information 2002 http://www.medscape.com/viewarticle/433886?srcmp=id-052402

EBV LEVELS IN HIV-POSITIVE PATIENTS ARE NOT REDUCED BY HAART THERAPY The proportion of HIV-infected patients with high levels of Epstein-Barr virus is not affected by HAART, Dutch investigators report. Reuters Health Information 2002 http://www.medscape.com/viewarticle/434104?srcmp=id-052402

INTERMITTENT USE OF ANTIRETROVIRAL THERAPY LINKED TO INCREASED MORTALITY HIV-positive individuals who skip triple-drug antiretroviral therapy or lower their doses intermittently have significantly increased mortality compared with those who follow their treatment regimen, according to the results of a population-based study. Reuters Health Information 2002 http://www.medscape.com/viewarticle/433818?srcmp=id-052402

PHENOTYPE TESTING URGED WHEN SWITCHING HIV-1 POSITIVE PATIENTS FROM AMPRENAVIR Researchers have found that amprenavir-resistant HIV-1 can be cross-resistant to lopinavir, which suggests that phenotypic resistance testing should be done in patients being switched from a failing amprenavir-containing regimen. Reuters Health Information 2002 http://www.medscape.com/viewarticle/434042?srcmp=id-052402

The longer and more complex the prenatal antiretroviral therapy, the more likely it is to prevent mother-to-child HIV-1 transmission, researchers report. Reuters Health Information 2002 http://www.medscape.com/viewarticle/433821?srcmp=id-052402

SEVERE DEMYELINATING LEUKOENCEPHALOPATHY MAY DEVELOP AFTER HAART FAILURE Clinicians are beginning to see cases of severe leukoencephalopathy among AIDS patients who are being treated with HAART. Reuters Health Information 2002 http://www.medscape.com/viewarticle/433969?srcmp=id-052402

REDUCED CONDOM USE SEEN AMONG GAY MEN ON HAART WITH A PI HIV-infected men who have sex with men and who are receiving HAART that includes a protease inhibitor appear to be more likely to use condoms inconsistently or not at all, compared with other HIV-infected individuals, researchers report. Reuters Health Information 2002 http://www.medscape.com/viewarticle/433729?srcmp=id-052402

Another 22 British servicemen in Afghanistan have reported ill with an unidentified disease that struck a field hospital this week, a British military official said on Friday. Reuters Health Information 2002 http://www.medscape.com/viewarticle/433795?srcmp=id-052402

ANTIMICROBIAL PEPTIDE ACTIVE AGAINST PSEUDOMONAS-INFECTED BURN WOUNDS The synthetic antimicrobial peptide D2A21 decreases the growth of Pseudomonas aeruginosa in rats with infected burn wounds, leading to dramatically increased survival. Reuters Health Information 2002 http://www.medscape.com/viewarticle/433953?srcmp=id-052402

Maryland researchers have uncovered clues to the therapeutic effects of an herb used in traditional Chinese medicine. Reuters Health Information 2002 http://www.medscape.com/viewarticle/434102?srcmp=id-052402

http://www.medscape.com/px/registration/profileindex

home page. Or click here: www.medscape.com/cmecenterdirectory

Unsubscribe or subscribe to MedPulse: http://www.medscape.com/profile (<A HREF="http://www.medscape.com/profile">Edit Your Profile</A>).

Forgot your login info?: http://www.medscape.com/password

Need additional support?: http://www.medscape.com/help/tech

Vaccination News Home Page

ALL INFORMATION, DATA, AND MATERIAL CONTAINED, PRESENTED, OR PROVIDED HERE IS FOR GENERAL INFORMATION PURPOSES ONLY AND IS NOT TO BE CONSTRUED AS REFLECTING THE KNOWLEDGE OR OPINIONS OF THE PUBLISHER, AND IS NOT TO BE CONSTRUED OR INTENDED AS PROVIDING MEDICAL OR LEGAL ADVICE.  THE DECISION WHETHER OR NOT TO VACCINATE IS AN IMPORTANT AND COMPLEX ISSUE AND SHOULD BE MADE BY YOU, AND YOU ALONE, IN CONSULTATION WITH YOUR HEALTH CARE PROVIDER.