Vaccinating children against chickenpox - an idea gaining favour in many
countries - could lead to the millions of cases of shingles in older
people, say UK researchers
In America, most children are vaccinated. A vaccine is also available
in Canada. Australia is considering the idea.
In Europe, there is little vaccination as chickenpox is seen as fairly
harmless.
Pharmaceutical company GlaxoSmithKline is developing a vaccine
combining chickenpox and the controversial triple measles, mumps and
rubella vaccine, but it will be at least two years before it is submitted
for licensing approval.
After having chickenpox, people retain the virus within their sensory
nerves.
It lies dormant there until a fall in immunity - which usually occurs
after the age of 60 - allows it to flare up again as shingles (herpes
zoster).
Children link
Around a quarter of people who have had chickenpox go on to suffer the
condition, which manifests itself as a painful rash.

There is no current plan to introduce universal immunisation against
chickenpox

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Department of Health spokeswoman
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Twenty per cent of them experience
severe and lasting pain.
But adults living with children are less likely to develop shingles
than those who do not.
This is because being exposed to children, and therefore chickenpox,
acts like a booster vaccine against shingles.
The researchers from the Public Health Laboratory Service in London
said if all children were vaccinated against chickenpox, adults who had
had the disease would not be exposed to enough of the virus to prevent
full-blown shingles later on.
They say that over the first 50 years, vaccinating a population the
size of the US would save 5,000 children from dying of the complications
of chickenpox.
But there would be 21m extra cases of shingles - and 5,000 people over
60 would die from complications associated with that condition.
John Edmunds, a member of the PHLS team, said: "Vaccination looks good
in terms of costs and benefits if you just look at the economic effect of
chickenpox, such as parents taking time off to look after children."
"But shingles has been ignored. If you include that, the costs and
benefits may not be very good at all."
UK - 'no plans'
A spokeswoman for the PHLS said it was looking at what the impact might
be of introducing a chickenpox vaccine in the UK.
As more evidence became available, it would be shared with the Joint
Committee on Vaccination and Immunisation which advises the Department of
Health, she said.
A Department of Health spokeswoman told BBC News Online: "There is no
current plan to introduce universal immunisation against chickenpox, but
we are aware of Dr Edmunds' work and will look at that."
In America, where vaccination was introduced in 1995, cases of
chickenpox have fallen by up to 80%.
Michael Oxman, of the University of California at San Diego, said: "I
started to support vaccination for chickenpox when I started seeing more
deaths from Group A streptococcus infections."
These bacteria, which is the main complication of chickenpox in
children, can cause toxic shock and the flesh-eating disease necrotising
fasciitis, and are becoming more virulent.
Dr Oxman said there could be a surge in shingles, but suggested a
solution could be to also vaccinate older people, something he is testing
in an ongoing study of 40,000 Americans over 60.
He said even if that did work, it might be difficult to persuade some,
particularly older men, to have their vaccinations.
The report is published in New Scientist and in the journal Vaccine.