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Vaccines to Alter Behavior

Cocaine Vaccine

Vaccines Against Cocaine in Cinical Tests — What’s Next?

Will there someday be a vaccine for obesity, coughing during concerts and sneering? Clinical tests are already under way for a cocaine vaccine. (Brian Garrigan/ABCNEWS.com)


Commentary
By Nicholas Regush

ABCNEWS.com
July 20 — Awesome. A new vaccine to blunt the pleasurable effects of cocaine. Clinical tests are already under way. And should it prevent the cocaine “high,” then the spotlight will hover over the delicate issue of who gets the injection.
    
Only those thought likely to become cocaine addicts? Every child? Every human on the face of the earth who might one day come in contact with cocaine?
     The cocaine vaccine competition includes an arresting version being tested by a scientific team at the Scripps Institute in California in La Jolla. The vaccine sets off the body’s immune system to attack the cocaine molecule with antibodies.
    These antibodies essentially blow up the molecule to a size that prevents it from entering the brain. And therefore the cocaine molecule will not trip dopamine, the body’s feel-good drug. Related cocaine vaccines already are actually being tested in humans.
     So much for the kick of cocaine. Unless, of course, someone is into chain-snorting of the drug. That extreme form of behavior could overpower the overall effects of a vaccine and buy a quick snap or two of chemical paradise. Vaccines under development that target pleasure appear to have limits. For now.

Medicalizing Our Foibles
But let us be optimistic. The final product, a powerful, no-nonsense cocaine vaccine might well set the pace for the unfolding New Medical Order, that blossoming movement to medicalize every conceivable sort of human behavior.
    Included in this pathologizing arena are actions considered to be sinful and even menacing to society, such as snorting cocaine and inhaling nicotine and marijuana. It could potentially expand to those human foibles widely perceived to be more irritating than devastating, including inappropriate, compulsive, public nose-picking and knuckle-cracking.
     Who, for example, could have predicted that doctors would prescribe a drug (Zoloft, an antidepressant) to combat shyness? In the fast-approaching medical era of “anything goes if you can find a smart way to humor public vulnerability,” the galaxies of opportunity are there for the taking. IPO enthusiasts, stay alert!
     So why not a new medication or some ingenious vaccine, say, to combat sneering? Too many people walk around sneering these days. Face it, it is socially uncouth and suggests an undertow of uncontrolled aggression.
     The National Institutes of Health, which has socked almost $5 million into cocaine vaccine research, could easily cough up a few million dollars more to discover the gene or brain chemicals that promote sneering and then finance clinical tests of appropriate treatment modalities. Believe me, it will make for a much happier world.

Other Target Vaccines?
Since we’re on the subject, here are a few more behaviors in no apparent ranking that can be considered ripe for medicalization:
        Talking with God (Godliness Syndrome).
        Having sex more than five times a week (Getoff Disease).
        Keeping one’s body in an obese state for more than one year (Naughty Body Disease).
        Saving $1 bills (Pre-Alzheimer’s Disease).
        Coughing during concert performances. (Coughus Interruptus Condition).
     I’m sure you can add to the list.
     Lest we forget the point to all this, let it be stated that anyone with a serious dysfunction that disrupts a healthy life, such as a cocaine addiction, may need medical help. The type of vaccine being tested might be of great benefit to those who can’t shake coke.
     But also let us not forget that this is a culture driven by the bottom line. There will be a hard push to inject a lot of people, including kids, with such a vaccine. Money, not health considerations, will likely rule the day.
     And where do we draw the line on medicalizing human behavior? Where the medical money wants us to.

 

Nicholas Regush

Nicholas Regush produces medical features for ABCNEWS. In his weekly column, published Thursdays, he looks at medical trouble spots, heralds innovative achievements and analyzes health trends that may greatly influence our lives. His latest book is The Virus Within.





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 ALL INFORMATION, DATA, AND MATERIAL CONTAINED, PRESENTED, OR PROVIDED HERE IS FOR GENERAL INFORMATION PURPOSES ONLY AND IS NOT TO BE CONSTRUED AS REFLECTING THE KNOWLEDGE OR OPINIONS OF THE PUBLISHER, AND IS NOT TO BE CONSTRUED OR INTENDED AS PROVIDING MEDICAL OR LEGAL ADVICE.  THE DECISION WHETHER OR NOT TO VACCINATE IS AN IMPORTANT AND COMPLEX ISSUE AND SHOULD BE MADE BY YOU, AND YOU ALONE, IN CONSULTATION WITH YOUR HEALTH CARE PROVIDER.