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Tuesday, March 13, 2001 | Print this story



Soaring Prices Curb Availability of Tetanus Vaccine
Health: Counties face cuts in immunization programs because state has been unable to buy adequate supplies.

By SHARON BERNSTEIN, Times Health Writer


     The state has been able to purchase and distribute just a third of its normal supply of tetanus/diphtheria vaccine--used mainly for unvaccinated schoolchildren--because the manufacturer has quadrupled the price.
     As a result, counties have been forced to either dramatically cut their immunization programs or purchase the extra vaccine at great cost, officials said Monday.
     "If we're not able to give it to those children who require it, we could possibly be building up a susceptible population," said John Dunajsky, assistant immunization branch chief for the state Department of Health Services.
     "There has been very little tetanus among children in schools since laws were passed [requiring immunization]. But if this continues, there is the possibility of building up a population of kids who aren't protected."
     The problem is compounded by a severe nationwide shortage of the vaccine, which is now produced by only one company, Aventis Pasteur of Swiftwater, Pa., the American arm of the French firm Aventis SA.
     Aventis Pasteur says it was forced to raise prices in 2000--affecting vaccines earmarked for use this year--because the vaccine was underpriced and the company had spent millions to modernize its manufacturing plants.
     California, which typically purchases about 210,000 doses of the vaccine each year and distributes them to county health departments, was able to buy just 70,025 doses for use in late 2000 and early 2001, said Natalie Smith, immunization branch chief of the state health department.
     Counties generally use the vaccines to immunize schoolchildren who did not receive them as infants, as well as youths and adults who have been exposed to tetanus or need booster shots. The vaccine is different from the one administered to infants; there is only a slight shortage of that vaccine, which protects against diphtheria, pertussis and tetanus.
     Because the state has cut back so severely on its purchases of the vaccine, Smith and her staff are allowing counties to use it for children only.
     To make matters worse, the federal government, which until 1999 purchased the vaccine at discounted rates and then resold it to states, no longer does so. Officials say the price has risen so high that it outstrips a federal limit on prices that the Centers for Disease Control and Prevention are allowed to pay for immunizations.
     "We used to have a stockpile" of the tetanus/diphtheria vaccine," said Robert Snyder, who is in charge of purchasing vaccines for the CDC's National Immunization Program. "But that changed when I could no longer buy it."
     Now, Snyder said, immunization programs in all 50 states are suffering.
     California, with its large populations of uninsured residents and immigrants who may not have been immunized as children, has been hit the hardest, he said.
     The shortage and price hikes have affected private doctors and hospitals as well. They too have begun rationing the vaccine.
     Aventis Pasteur has given priority in distribution to emergency rooms