http://www.nytimes.com/2001/04/25/health/25CONF.html
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In reviewing 61,134 scholarly articles published in 181 academic
journals in 1997, researchers at Tufts University and the University of
California at Los Angeles found that just one-half of 1 percent detailed
personal financial interests, including consulting arrangements,
honorariums, expert witness fees, company equity and stock, and patents. All
of those few disclosures appeared in just a third of the 181 journals. It is possible, of course, that scientists have few conflicts to report.
But experts say previous studies have shown that as many as half of all
academic researchers consult with industry, and roughly 8 percent have
stakes in biomedical companies related to their research. So the more likely explanation, said Dr. Sheldon Krimsky, a professor of
urban and environmental policy at Tufts and the study's lead author, is
that journal editors "are not forceful enough" in requiring
disclosure, "or there is widespread disobedience" of their rules.
Dr. Krimsky's study appears in the April issue of Science and
Engineering Ethics, a journal that was not part of his survey. It comes at a time of increasing concern about the effects of
commercialization of science. And the findings are not surprising, said Dr.
David Blumenthal, director of the Institute for Health Policy, a research
center at Massachusetts General Hospital. Dr. Blumenthal, who studies the ties between academia and industry, said
that scientists who failed to report conflicts generally "believe that
they are people of integrity, and they feel they can separate their work
from their financial interests." But research suggests otherwise, Dr. Blumenthal said. Studies have found
that scientists with financial ties to the companies whose products they
study are more likely to write favorably about those products. The issue of financial disclosure has been in the news of late; last year,
the editors of The New England Journal of Medicine apologized to readers
for violating their own conflict-of-interest policies by publishing reviews
of the medical literature on drug therapies despite the reviewers'
financial relationships with the companies marketing the drugs. Dr. Jeffrey M. Drazen, The Journal's editor in chief, said that
persuading scientists to divulge personal financial data was not easy.
"We have to work at it," he said. When researchers ignore
inquiries about conflicts, he said, many journals, including his own,
assume none exist. Dr. Drazen said editors of journals around the world would meet in May
and discuss whether researchers should be required to submit either a
disclosure of conflict or what he called an "active negative
disclosure," -- a declaration that the researcher is free of financial
conflict.
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