The discovery of unexpected similarities between dozens of different
viruses has produced the distant prospect of a "universal" treatment.
Bacteria, despite causing hundreds of different types of infection,
essentially reproduce and spread in the same way.
A single "broad spectrum" antibiotic may be able to tackle dozens of
different types.
However, viruses are split into seven different main types - all of
which use widely differing methods to replicate.
Common threads
Creating a drug which can tackle each class is enough of a challenge -
but making one which can handle more than one class is seen as a much
greater problem.
However, researchers at the Howard Hughes Medical Institute in the US
believe they have found a common process that links three of the virus
types.

The eventual hope might be for a general-purpose antiviral drug
which could perhaps be given by GPs for a wide range of viral
infections

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Dr Alan Cann, Leicester University
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Between them, this group covers the
majority of viruses which cause disease in humans, including hepatitis B
and C, polio, HIV, and even haemorrhagic fevers such as Ebola.
Studies of the replication process of the virus by the Howard Hughes
Institute researchers revealed that, while each type used different
genetic tricks to copy itself, one vital stage of the process involved
creating a "bud" to contain genetic material from the virus.
The researchers believe that a future drug which disrupted the
formation of the "bud" could hold the key to interrupting the progress of
dozens of viruses.
Long wait
Researcher Paul Ahlquist said: "Recognition of these links means that
principles learned from a variety of virus systems could be used to
illuminate many others, allowing integration and generalisation of
knowledge across a wide range of important viruses."
He did concede that much remained to be done before new treatments
could be developed.
Dr Alan Cann, a virologist from the University of Leicester, agreed
that many hurdles had to be overcome before new "broad spectrum" antiviral
drugs could be developed.
He said: "The biggest problem for antiviral drugs is that viruses are
so tied into the biochemistry of human cells.
"It's hard to find a way to harm them without being toxic to the cell
itself.
"The eventual hope might be for a general-purpose antiviral drug which
could perhaps be given by GPs for a wide range of viral infections.
"This is likely to take a long time to produce."
The research was published in the journal Molecular Cell.