Type 1 diabetes: virus infection or autoimmune disease?

http://www.nature.com/cgi-taf/DynaPage.taf?file=/ni/journal/v3/n4/abs/ni0402-338_fs.html&filetype=&_UserReference=C0A804EF4650B17747B3C8A002213CA264C5

 

Volume 3 No 4 - April 2002
 

News & Views

Nature Immunology 3, 338 - 340 (2002)
DOI:10.1038/ni0402-338
© Nature America, Inc.

Type 1 diabetes: virus infection or autoimmune disease?

DeLisa Fairweather & Noel R. Rose
 

Departments of Pathology and of Molecular Microbiology & Immunology, Johns Hopkins Medical Institutions, Baltimore, MD 21205 USA.
 nrrose@jhsph.edu
 

What does Coxsackie virus have to do with diabetes? Evidence is emerging that insulin-producing beta cells are highly susceptible to acute infection by Coxsackie virus if their production of interferon is inhibited, resulting in diabetes.

ALL INFORMATION, DATA, AND MATERIAL CONTAINED, PRESENTED, OR PROVIDED HERE IS FOR GENERAL INFORMATION PURPOSES ONLY AND IS NOT TO BE CONSTRUED AS REFLECTING THE KNOWLEDGE OR OPINIONS OF THE PUBLISHER, AND IS NOT TO BE CONSTRUED OR INTENDED AS PROVIDING MEDICAL OR LEGAL ADVICE.  THE DECISION WHETHER OR NOT TO VACCINATE IS AN IMPORTANT AND COMPLEX ISSUE AND SHOULD BE MADE BY YOU, AND YOU ALONE, IN CONSULTATION WITH YOUR HEALTH CARE PROVIDER.