MEDSCAPE's Pediatrics MedPulse(R) March 29, 2002

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extensive online CME resources -- more than 100 activities at any one time,

all of them free. CME activities that have been recently posted or are of

particular interest in Pediatrics include:

MEASLES, HAEMOPHILUS INFLUENZAE TYPE B, VARICELLA: PRE- AND POSTVACCINE EPIDEMIOLOGY IN THE UNITED STATES

Routine childhood vaccination ranks as the number 1 public health achievement in the United States in the last century. Review the effects that the measels, Haemophilus influenzae type b (HIB), and varicella vaccines have had on disease epidemiology. http://www.medscape.com/viewprogram/596?srcmp=ped-032202

<a href="http://www.medscape.com/viewprogram/596?srcmp=ped-032202"> Read it Here</a>

THERAPEUTIC OPTIONS IN AN ERA OF EVOLVING HOSPITAL BACTERIAL SUSCEPTIBILITY PATTERNS Careful management of febrile neutropenic patients as well as appropriate selection of antibiotic therapies can help to reduce bacterial infection in hospitalized patients. http://www.medscape.com/viewprogram/156?srcmp=ped-032202

<a href="http://www.medscape.com/viewprogram/156?srcmp=ped-032202"> Read it Here</a>

INNOVATIVE EPILEPSY THERAPIES FOR THE 21ST CENTURY

Reevaluating the current medical and surgical options for epilepsy, with a look toward the latest in drug development strategies.

http://www.medscape.com/viewprogram/234?srcmp=ped-032202

<a href="http://www.medscape.com/viewprogram/234?srcmp=ped-032202"> Read it Here</a>

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MedPulse is a weekly index of key news and features on Medscape's specialty sites compiled by Medscape's Editors. _______________________________________________________________________

___________________ NEW FEATURE ARTICLES THIS WEEK ____________________

MATERNAL ESTIMATES OF NEONATAL BIRTH WEIGHT IN DIABETIC PATIENTS Learn about the accuracy of maternal, clinical and ultrasonographic assessment of fetal weight in diabetic women. South Med J 95(1) 2002 http://www.medscape.com/viewarticle/426980?srcmp=ped-032202

<a href="http://www.medscape.com/viewarticle/426980?srcmp=ped-032202">

Read it Here</a>

CAROTID ARTERY INTIMA-MEDIA THICKNESS IN CHILDREN WITH TYPE 1 DIABETES Studies have shown that the atherosclerotic process begins in childhood and is hastened in the presence of risk factors. Diabetes 51(2) 2002 http://www.medscape.com/viewarticle/427738?srcmp=ped-032202

<a href="http://www.medscape.com/viewarticle/427738?srcmp=ped-032202">

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ACQUIRED RIFAMYCIN RESISTANCE IN PERSONS WITH ADVANCED HIV DISEASE BEING TREATED FOR ACTIVE TUBERCULOSIS WITH INTERMITTENT RIFAMYCIN-BASED REGIMENS Persons with HIV-TB and low CD4 counts should receive daily therapy during the intensive phase. MMWR 51(10) 2002 http://www.medscape.com/viewarticle/430134?srcmp=ped-032202

<a href="http://www.medscape.com/viewarticle/430134?srcmp=ped-032202">

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THERAPY WITH MACROLIDES IN PATIENTS WITH CYSTIC FIBROSIS Macrolides could have a tremendous impact on the quality of life of patients with cystic fibrosis. Pharmacotherapy 22(2) 2002 http://www.medscape.com/viewarticle/427440?srcmp=ped-032202

<a href="http://www.medscape.com/viewarticle/427440?srcmp=ped-032202">

Read it Here</a>

VACCINE SUPPLY UPDATE

Due to a shortage of some pediatric vaccines in 2001, the ACIP has revised recommendations for administration. Infect Med 19(1) 2002 http://www.medscape.com/viewarticle/423500?srcmp=ped-032202

<a href="http://www.medscape.com/viewarticle/423500?srcmp=ped-032202">

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SUPPORT FOR WHEN MENINGITIS STRIKES

Several organizations are promoting awareness of meningitis and its grave, sometimes life-threatening consequences. Medscape Infectious Diseases 4(1) 2002 http://www.medscape.com/viewarticle/430000?srcmp=ped-032202

<a href="http://www.medscape.com/viewarticle/430000?srcmp=ped-032202">

Read it Here</a>

A CALL FOR HELP: MEDICAL BOOKS, JOURNALS, AND SUPPLIES NEEDED IN AFGHANISTAN Will you help provide medical facilities in Afghanistan with needed medical books, journals, and supplies? Medscape Nurses 4(1) 2002 http://www.medscape.com/viewarticle/430320?srcmp=ped-032202

<a href="http://www.medscape.com/viewarticle/430320?srcmp=ped-032202">

Read it Here</a>

 

ROLE OF CORPECTOMY FOR MANAGING CERVICAL SPONDYLOSIS

Surgical advances have expanded the role of corpectomy for managing

cervical spondylosis. Review indications, techniques, complications,

and outcomes in "Role of Corpectomy in Cervical Spondylosis," a new

article in the Medscape Spine Disorders Resource Center at

http://www.medscape.com/mp/rc/spine

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___________________________________ NEWS ______________________________

 

--Fetal, Neonatal, and Infant Health--

ONE EMBRYO DOES NOT IMPAIR DEVELOPMENT OF ITS TWIN

Dizygotic twins are at no disadvantage during early embryonic development compared with singletons. Reuters Health Information 2002 http://www.medscape.com/viewarticle/430180?srcmp=ped-032202

<a href="http://www.medscape.com/viewarticle/430180?srcmp=ped-032202">

Read it Here</a>

IVF DOES NOT INCREASE CANCER RISK IN MOTHERS OR OFFSPRING Results of two studies by the same research group show that is no excess risk of gynecologic cancer among women undergoing in vitro fertilization or of childhood cancer among their offspring. Reuters Health Information 2002 http://www.medscape.com/viewarticle/430283?srcmp=ped-032202

<a href="http://www.medscape.com/viewarticle/430283?srcmp=ped-032202">

Read it Here</a>

IN UTERO VACCINATION STRATEGY MAY HELP PREVENT VERTICAL DISEASE TRANSMISSION Oral DNA vaccination in utero can induce mucosal and systemic immune responses in the neonate that may help prevent vertical disease transmission. Reuters Health Information 2002 http://www.medscape.com/viewarticle/430241?srcmp=ped-032202

<a href="http://www.medscape.com/viewarticle/430241?srcmp=ped-032202">

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TREATMENT OF PLACENTAL INFLAMMATION MIGHT REDUCE HIV VERTICAL TRANSMISSION RATE Nearly 9% of HIV-infected pregnant women living in Kenya develop acute chorioamnionitis. Treatment of this condition might be expected to reduce the overall HIV vertical transmission rate by about 3%. Reuters Health Information 2002 http://www.medscape.com/viewarticle/430357?srcmp=ped-032202

<a href="http://www.medscape.com/viewarticle/430357?srcmp=ped-032202">

Read it Here</a>

NEUROBLASTOMA SCREENING IN INFANTS YIELDS MARGINAL REDUCTION IN MORTALITY Screening for neuroblastoma at 6 months of age is associated with a dramatic increase in disease diagnosis but only a marginal decrease in mortality. Reuters Health Information 2002 http://www.medscape.com/viewarticle/430344?srcmp=ped-032202

<a href="http://www.medscape.com/viewarticle/430344?srcmp=ped-032202">

Read it Here</a>

 

 

--Childhood and Adolescent Health--

PUBERTAL STATUS INFLUENCES INSULIN PUMP DOSING IN DIABETIC CHILDREN In children with type I diabetes, pubertal status influences the total daily insulin dose needed when converting from multiple daily injections to continuous subcutaneous insulin infusion (CSII). Reuters Health Information 2002 http://www.medscape.com/viewarticle/430291?srcmp=ped-032202

<a href="http://www.medscape.com/viewarticle/430291?srcmp=ped-032202">

Read it Here</a>

VITAMIN D DEPLETION CONTRIBUTES TO OSTEOPENIA IN CHILD SURVIVORS OF SEVERE BURNS Low serum levels of 25-hydroxyvitamin D are associated with low bone mineral density in children who have been burned over more than 40% of their total body surface area. Reuters Health Information 2002 http://www.medscape.com/viewarticle/430166?srcmp=ped-032202

<a href="http://www.medscape.com/viewarticle/430166?srcmp=ped-032202">

Read it Here</a>

LAPAROSCOPIC APPENDECTOMY UNRELATED TO INCREASED ABSCESS RISK IN CHILDREN The rate of intra-abdominal abscess (IAA) formation in children after laparoscopic appendectomy is similar to that following open appendectomy. Reuters Health Information 2002 http://www.medscape.com/viewarticle/430177?srcmp=ped-032202

<a href="http://www.medscape.com/viewarticle/430177?srcmp=ped-032202">

Read it Here</a>

DAY CARE ATTENDANCE SEEMS TO PROTECT AGAINST THE DEVELOPMENT OF ATOPY Among children with atopic parents, the protective effect of day care attendance in the first year of life against the development of atopy begins by 2 years of age. Reuters Health Information 2002 http://www.medscape.com/viewarticle/430239?srcmp=ped-032202

<a href="http://www.medscape.com/viewarticle/430239?srcmp=ped-032202">

Read it Here</a>

HUMAN GROWTH HORMONE 'OVERUSED' IN UK CHILDREN

More than one-in-five children treated with growth hormone in Britain are being given it for unlicensed reasons and are unlikely to gain much extra height. Reuters Health Information 2002 http://www.medscape.com/viewarticle/430347?srcmp=ped-032202

<a href="http://www.medscape.com/viewarticle/430347?srcmp=ped-032202">

Read it Here</a>

 

--Public Policy Issues--

FDA WANTS TO SUSPEND PEDIATRIC STUDY RULE

US health officials said they planned to suspend a rule that requires drug companies to study how the medicines they make affect children, drawing swift criticism from Democrats. Reuters Health Information 2002 http://www.medscape.com/viewarticle/430278?srcmp=ped-032202

<a href="http://www.medscape.com/viewarticle/430278?srcmp=ped-032202">

Read it Here</a>

SUBSPECIALISTS OUTSIDE SPECIALTY MAY BE LESS EFFICIENT, PROVIDE LESS QUALITY CARE Subspecialists practicing outside their subspecialty are likely to have patients that stay in the hospital longer than general internists or subspecialists practicing within their subspecialty. Reuters Health Information 2002 http://www.medscape.com/viewarticle/430300?srcmp=ped-032202

<a href="http://www.medscape.com/viewarticle/430300?srcmp=ped-032202">

Read it Here</a>

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ALL INFORMATION, DATA, AND MATERIAL CONTAINED, PRESENTED, OR PROVIDED HERE IS FOR GENERAL INFORMATION PURPOSES ONLY AND IS NOT TO BE CONSTRUED AS REFLECTING THE KNOWLEDGE OR OPINIONS OF THE PUBLISHER, AND IS NOT TO BE CONSTRUED OR INTENDED AS PROVIDING MEDICAL OR LEGAL ADVICE.  THE DECISION WHETHER OR NOT TO VACCINATE IS AN IMPORTANT AND COMPLEX ISSUE AND SHOULD BE MADE BY YOU, AND YOU ALONE, IN CONSULTATION WITH YOUR HEALTH CARE PROVIDER.