MEDSCAPE's Pediatrics MedPulse 3-7-02

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MedPulse is a weekly index of key news and features on Medscape's specialty sites compiled by Medscape's Editors. _______________________________________________________________________

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WOMEN AND PSYCHOPHARMACOLOGY

A practical review for clinicians who prescribe psychotropic medication to their female patients, especially during pregnancy. Medscape Women's Health eJournal 7(1) 2002 http://www.medscape.com/viewarticle/423938?srcmp=ped-030102

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CASE 11: COULD THIS BE GUILLAIN-BARRE SYNDROME?

What's wrong with this toddler?

Medscape Neurology & Neurosurgery 4(1) 2002 http://www.medscape.com/viewarticle/424997?srcmp=ped-030102

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BARRIERS TO DIETARY CONTROL AMONG PREGNANT WOMEN WITH PHENYLKETONURIA -- UNITED STATES, 1998--2000 It is important to control blood phenylalanine levels before and during pregnancy to prevent mental retardation. MMWR 51(6) 2002 http://www.medscape.com/viewarticle/425977?srcmp=ped-030102

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EFFECT OF METFORMIN IN PEDIATRIC PATIENTS WITH TYPE 2 DIABETES: A RANDOMIZED CONTROLLED TRIAL Should metformin be considered as an alternative to insulin therapy for children with type 2 diabetes? Diabetes Care 25(1) 2002 http://www.medscape.com/viewarticle/424457?srcmp=ped-030102

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CSAP STUDY FINDS PREVENTION PROGRAMS EFFECTIVE

Prevention programs for high-risk youth have been effective in reducing rates of alcohol, tobacco, and marijuana use. Alcoholism & Drug Abuse Weekly 14(7) 2002 http://www.medscape.com/viewarticle/425777?srcmp=ped-030102

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SEPSIS RESOURCE CENTER ON MEDSCAPE

The Sepsis Resource Center gives the latest on pathophysiology,

diagnosis, prevention, and treatment, plus news and related

resources for sepsis.

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___________________________________ NEWS ______________________________

--Fetus/Neonate--

OBESITY BEFORE PREGNANCY PUTS WOMEN AND INFANTS AT RISK

Losing weight before pregnancy could increase both maternal and infant health. MedscapeWire 2002 http://www.medscape.com/viewarticle/429052?srcmp=ped-030102

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SOUTH AFRICA REPORT GIVES GREEN LIGHT FOR NEVIRAPINE PROGRAM South Africa released a report stating that its nevirapine trial programme to prevent vertical HIV transmission is safe and should be extended to other sites. Reuters Health Information 2002 http://www.medscape.com/viewarticle/429207?srcmp=ped-030102

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MATERNAL INJECTION DRUG USE INCREASES RISK OF VERTICAL HEPATITIS C TRANSMISSION Maternal injection drug use, but not co-infection with HIV, significantly increases the risk of hepatitis C virus (HCV) transmission to a fetus. Reuters Health Information 2002 http://www.medscape.com/viewarticle/428958?srcmp=ped-030102

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SKIN COLONIZATION WITH MALASSEZIA SPECIES COMMONLY OCCURS AT BIRTH Skin colonization with Malassezia species, yeast flora linked to the development of cephalic pustulosis, begins during the first days of life. Reuters Health Information 2002 http://www.medscape.com/viewarticle/429320?srcmp=ped-030102

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--Infants--

NONSURGICAL MANAGEMENT OF INFANT CLUBFOOT YIELDS EXCELLENT RESULTS Using a series of casts to progressively modify pronation and internal rotation of the foot, orthopedic surgeons are reporting excellent results with the nonsurgical correction of clubfoot in infants. Reuters Health Information 2002 http://www.medscape.com/viewarticle/429202?srcmp=ped-030102

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FINDINGS ON DIFFUSION-WEIGHTED MRI MAY POINT TO SHAKEN-BABY SYNDROME Conducting diffusion-weighted MRI scans immediately upon admission for suspicion of shaken-baby syndrome adds crucial information needed for diagnosis. Reuters Health Information 2002 http://www.medscape.com/viewarticle/429032?srcmp=ped-030102

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CONSERVATIVE MEASURES NOT PROVEN TO RELIEVE REFLUX IN INFANTS Changes in infant positioning, changes in feeding, and other conservative measures do not have proven efficacy against gastroesophageal reflux disease in infants. Reuters Health Information 2002 http://www.medscape.com/viewarticle/429037?srcmp=ped-030102

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--Children and Adolescents--

DAY CARE HELPS BOOST IMMUNITY

Children who attend day care experience far fewer colds in elementary school later. MedscapeWire 2002 http://www.medscape.com/viewarticle/427217?srcmp=ped-030102

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ABACAVIR-BASED REGIMENS SHOW PROMISE FOR TREATMENT OF HIV-INFECTED CHILDREN Antiretroviral therapy containing the reverse transcriptase inhibitor abacavir may be an important first-line therapy in children infected with HIV-1. Reuters Health Information 2002 http://www.medscape.com/viewarticle/429313?srcmp=ped-030102

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SPECIFIC STRAIN OF S. AUREUS TIED TO LETHAL NECROTIZING PNEUMONIA IN YOUNG PATIENTS A French research team has found that the strain of Staphylococcus aureus that carries the gene for Panton-Valentine leukocidin (PVL) is associated with a rapidly progressive, hemorrhagic, necrotizing pneumonia found in children and young adults. Reuters Health Information 2002 http://www.medscape.com/viewarticle/429317?srcmp=ped-030102

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ADHD MANIFESTATIONS IN PRESCHOOL CHILDREN SIMILAR TO THOSE IN OLDER CHILDREN Preschool children with attention-deficit/hyperactivity disorder (ADHD) are similar to older children with ADHD in terms of disease severity, impaired functioning, and psychiatric comorbidity rates. Reuters Health Information 2002 http://www.medscape.com/viewarticle/429312?srcmp=ped-030102

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STIMULANTS MAY TREAT ADHD, TIC DISORDERS

Children with ADHD and tic disorders may be effectively treated with stimulants. MedscapeWire 2002 http://www.medscape.com/viewarticle/429050?srcmp=ped-030102

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MEASLES OUTBREAK HITS GERMAN REGION, ATTRIBUTED TO MMR OPPOSITION 'Militant' opposition to the combined measles, mumps and rubella (MMR) vaccine is at least partly responsible for an outbreak of measles in a rural district of southern Bavaria. Reuters Health Information 2002 http://www.medscape.com/viewarticle/429286?srcmp=ped-030102

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WHEEZING IN LATE CHILDHOOD TIED TO ADULT ASTHMA

Although wheezing in early childhood often remits, such symptoms at the age of 11 years are associated with asthma in adulthood in individuals at high risk for atopy. Reuters Health Information 2002 http://www.medscape.com/viewarticle/429299?srcmp=ped-030102

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NEUROMUSCULAR TRAINING REDUCES ACL INJURY RISK BY 88% IN FEMALE ATHLETES Girls and women who play soccer, basketball, or volleyball are two to eight times more likely to injure the anterior cruciate ligament (ACL) than boys and men playing the same sports in the same positions. Reuters Health Information 2002 http://www.medscape.com/viewarticle/428962?srcmp=ped-030102

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EBV ROLE IN PATHOGENESIS OF HODGKIN'S DISEASE?

Is Epstein-Barr virus (EBV) detectable in plasma of patients with

Hodgkin's disease? Investigators in Germany evaluated this association

at the molecular level, analyzing EBV status in peripheral blood of 40

children. Review findings in an original Medscape Journal Scan summary,

available at: http://www.medscape.com/viewarticle/412617

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ALL INFORMATION, DATA, AND MATERIAL CONTAINED, PRESENTED, OR PROVIDED HERE IS FOR GENERAL INFORMATION PURPOSES ONLY AND IS NOT TO BE CONSTRUED AS REFLECTING THE KNOWLEDGE OR OPINIONS OF THE PUBLISHER, AND IS NOT TO BE CONSTRUED OR INTENDED AS PROVIDING MEDICAL OR LEGAL ADVICE. THE DECISION WHETHER OR NOT TO VACCINATE IS AN IMPORTANT AND COMPLEX ISSUE AND SHOULD BE MADE BY YOU, AND YOU ALONE, IN CONSULTATION WITH YOUR HEALTH CARE PROVIDER.