http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6792699&form=6&db=m&Dopt=b
[Convulsions after whooping-cough vaccination]
[Article in German]
Tonz O, Bajc S.
Convulsions or status epilepticus in 11 infants after pertussis vaccination are
reported. In 3 cases grand mal epilepsy persisted and 2 children developed
infantile epileptic encephalopathy (Lennox syndrome). On the basis of our own
experience, the incidence of seizures approximates 1:4800 infants vaccinated or
1:12 800 vaccinations. According to a recent prospective study from the USA, the
incidence of seizures may be closer to 1:600 infants. Since there is a
significant difference between the incidence of spontaneous fits in children of
the same age group and the incidence after vaccination, a causal relationship
between the seizures and vaccination appears to be confirmed. The following
conclusions are drawn from these observations: 1. In view of the usually benign
course of whooping cough today, current vaccination against pertussis is hardly
satisfactory. Improvement of the available vaccines is an urgent necessity. The
protection should include the population most at risk, i.e. infants during the
first few months of life. 2. Parents should be better informed about the risks
involved in pertussis vaccination. 3. Booster inoculations should be abandoned.
4. Health authorities should decide whether the current pertussis vaccination
program should be continued. 5. Complications following vaccination should be
registered at a national centre.
PMID: 6792699 [PubMed - indexed for MEDLINE]
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