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Vaccines and Immune Suppression citations
Auwaerter PG, Hussey GD, Goddard EA, Hughes J, Ryon JJ, Strebel
PM, Beatty D, Griffin DE. Changes within T cell receptor V
beta subsets in infants following measles vaccination.
Clin Immunol Immunopathol. 1996 May;79(2):163-70. PMID: 8620622
Measles produces immune suppression which contributes to an
increased susceptibility to other infections. Recently, high titered measles
vaccines have been linked to increased long-term mortality among some female
recipients.... [The following citation, Martinez X et al.,reiterates that
vaccinations can impair cell-mediated immunity by shifting cytokines release
into a Th2 pattern, thereby allowing intracellular pathogens (eg, many viruses)
to be more successful. We note that the authors of this 1997 study are trying to
devise a way around the general immune-impairing effect of conventional
vaccinations.]--Teresa Binstock
Beckenhauer, W H, et al, "Immunosuppression with Combined Vaccines", J AM
Vet Med Assoc, Aug 15, 1983, 183(4):389-390.
Blumberg DA, "Leukocyte responses to diphtheria-tetanus- pertussis and
diphtheria-tetanus immunization", Pediatr Infect Dis J 1991 Mar; 10(3):247-248.
Bastin, R et al, "Repeated Cholera Vaccination Immunological "Depressive" effect," Ann Med Interne (Paris), Jun-July 1974, 125(6-7):513-518.
Castan, P et al, "Coma Revealing an acute Leukosis in a child, 15 days after an Oral Anti-poliomyelitis Vaccination," Acta Neurol Bekg, May 1965, 65:349-367.
Dankova E, et al. [Immunologic findings in children with abnormal reactions after vaccination]. Cesk Pediatr. 1993 Jan;48(1):9-12. Czech.PMID: 8477472; UI: 93238311.
Daniliuk, O S et al, "Immunodepressive action Vaccinia Virus", Biull Eksp Biol Med, Jul 1982, 94(7):73-74.
Ehrland, W, "Susceptibility to Infection After Vaccination", Br Med J, Mar 11, 1972, 1:683.
Eibl MM, Mannhalter JW, Zlabinger G. Abnormal T-lymphocyte
subpopulations in healthy subjects after tetanus booster immunization.N
Engl J Med. 1984 Jan 19;310(3):198-9. No abstract available.PMID: 6228737 [PubMed
- indexed for MEDLINE]
"As reported in a letter to the New
England Journal of Medicine in 1984, tests of T-lymphocyte subpopulations were
done on 11 healthy adults before-and-after routine tetanus booster
immunizations. Tests showed a significant though temporary drop in T-helper
lymphocytes (a class of white blood cells which helps govern the immune system)
in all of the subjects. Special concern rests in the fact that in 4 of the
subjects the T-helper cells fell to levels found in active AIDS patients. (2) If
this was the result of a single vaccine in healthy adults, it is sobering to
think of the consequences of the multiple vaccines (twenty-one at last count)
routinely given to infants with their immature systems during the first six
months of life. However, we can only speculate as to the consequences, as this
test has never been repeated."--Dr
Buttram MD
Fattom, A, Cho, Y.H, Chu, C.Y, Fuller, S, Fries, L, Naso, R,
"Vaccines May Cause Immune Suppression ....", Vaccine, Jan 1999;17(2):126-133.
Futton, A et al, "Vaccines May Cause Immune Suppression", Vaccine, Jan 1999,
17(2):126-133.
Green, MS, et al , "Depression of Immune Response to an Inactivated Hepatitis A Vaccine Administered Concomitantly with Immune Globulin", J Infect Dis, 1993 Sep; 168(3):740-743.
Hussey GD, Goddard EA, Hughes J, Ryon JJ, Kerran M, Carelse E, Strebel PM,
Markowitz LE, Moodie J, Barron P, Latief Z, Sayed R, Beatty D, Griffin DE.
The effect of Edmonston-Zagreb and Schwarz measles vaccines on immune response
in infants. J Infect Dis. 1996 Jun;173(6):1320-6. PMID:
8648203
Eighty-eight children were immunized at 6 or 9 months of age with the
Edmonston-Zagreb (EZ) or Schwarz (SW6, SW9) strain of measles vaccine. Children
were studied before and 2 weeks and 3 months after immunization. ...Mitogen-induced
lymphoproliferation was decreased at 2 weeks in the SW9 group and at 3 months in
all groups and was negatively correlated with measles antibody level at 3 months
(r = -.387, P = .003). CD8 T cells, soluble CD8, neopterin, and
beta2-microglobulin were increased at 2 weeks in the SW9 group, and soluble CD8
and beta2-microglobulin remained elevated at 3 months. Therefore, measles
immunization resulted in suppression of lymphoproliferation, which was most
evident in infants with the highest antibody responses and most immune
activation.
Kumar, L et al, "Cell-Mediated Immuno-deficiency with Normal Immunoglobulins (Nezelof’s Syndrome) with Progressive Vaccinia", Indian Pediatr, Jan 1977, 14 (1):69-72.
Kotwal, G j et al, "Inhibition of the Complement Cascade by the Major Secretory Protein of Vaccinia Virus", Science, Nov 9, 1990, 250(4982):827-830.
Martinez X et al. DNA immunization circumvents deficient induction of T helper type 1 and cytotoxic T lymphocyte responses in neonates and during early life. Proc of the National Academy of Sciences 94.8726-31 1997. ab: The relative deficiency of T helper type 1 (Th1) and cytotoxic T lymphocyte (CTL) responses in early life is associated with an increased susceptibility to infections by intracellular microorganisms. This is likely to reflect a preferential polarization of immature CD4 T cells toward a Th2 rather than a Th1 pattern upon immunization with conventional vaccines...
Munyer, et al, "Depressed Lymphocyte Function after Measles-Mumps-Rubella Vaccination", Jour Infection Disorder, vol 132, No 1, July 1975, p 75-80.
Nakayama T, Urano T, Osano M, Maehara N, Sasaki K, Makino S.
Long-term regulation of interferon production by lymphocytes from children
inoculated with live measles virus vaccine. J Infect Dis.
1988 Dec;158(6):1386-90. No abstract available. PMID: 3143767
In the study, one-year-old infants were vaccinated with the
measles vaccine. This caused a huge drop in the level of alpha-interferon
produced by lymphocytes. Not only that, this harmful reduction in interferon
production lasted for an entire year, at which time the experiment was ended.
Conclusion: The study showed that the measles vaccine produced a significant
long-term immune suppression.
Oski and Naiman, "Effect of Live Measles Vaccine on the
Platelet Count", NEJM, Aug 18, 1966, p 352-356.
Reik, L Jr, "Disseminated Vasculomyelinopathy: An Immune Complex Disease", Ann
Neurol, Apr 1980, 7(4):291- 296.
Pletsityl, DF, et al, "The Effect of the Vaccinal Process on the Non-specific Phagocytic Activity of Peripheral Blood Leukocytes", Biull Eksp Biol Med, Mar 1973, 75(3):76-79.
Strauss, J et al, "Loss of Maternal Measles Antibodies
Acquired By Vaccination Against Measles," Cesk epidemiol Mikrobiol Immunol, May
1991, 40(3):137-143.
Stickl, H, "Iatrogenic Immunosuppression as a Result of Vaccination", Fortschr
Med, Mar 5, 1981, 99(9):289-292.
Children", Acta Paediatr, 1992 Nov; 81(11):887-890.
Toraldo, R, et al, "Effect of Measles-Mumps-Rubella Vaccination on Polymorphonuclear Neutrophil Functions in
Wilkins and Wehrle, "Additional Evidence Against Measles
Vaccine Administration to Infants Less than 12 months of Age: Altered Immune
Response Following Active- Passive Immunization, Jour Ped, 1979, Vol 94, p
865-869.
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