MEDSCAPE's Infectious Diseases MedPulse(R) 6-26-02

Vaccination News Home Page

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MedPulse is a weekly index of key news and features on Medscape's
specialty sites compiled by Medscape's Editors.
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___________________ NEW FEATURE ARTICLES THIS WEEK ____________________

-- MEDSCAPE ORIGINAL ARTICLES --

JOURNAL SCAN - INFECTIOUS DISEASES, JUNE 2002
Read reviews of recent literature by David Haburchak, MD, including:
- The Case of the Contaminated Fentanyl
- Updated Anthrax Management Recommendations
- Mycobacterial Furunculosis and a Nail Salon
- Outbreak of Poliomyelitis in Hispaniola
Medscape Infectious Diseases 4(1) 2002
medscape.com/viewarticle/436546?srcmp=id-062102

-- EMERGING INFECTIOUS DISEASES --

S PNEUMONIAE, BROOKLYN, NEW YORK: FLUOROQUINOLONE RESISTANCE AT OUR DOORSTEP
Brooklyn residents appear to be at high risk for fluoroquinolone-resistant S. pneumoniae.
Emerg Infect Dis 8(6) 2002
medscape.com/viewarticle/434413?srcmp=id-062102

TRENDS IN FLUOROQUINOLONE (CIPROFLOXACIN) RESISTANCE IN ENTEROBACTERIACEAE FROM BACTEREMIAS, ENGLAND AND WALES, 1990-1999
Resistance in Klebsiella rose from 3.5% in 1990 to 7.1% in 1999, and in Enterobacter from 2.1% in 1990 to 10.9% in 1999.
Emerg Infect Dis 8(5) 2002
medscape.com/viewarticle/432524?srcmp=id-062102

DROUGHT-INDUCED AMPLIFICATION OF SAINT LOUIS ENCEPHALITIS VIRUS, FLORIDA
During extended spring droughts, mosquitoes and wild birds congregate in selected refuges, facilitating amplification.
Emerg Infect Dis 8(6) 2002
medscape.com/viewarticle/434409?srcmp=id-062102

PHYLOGENETIC ANALYSIS OF A HUMAN ISOLATE FROM THE 2000 ISRAEL WEST NILE VIRUS EPIDEMIC
This isolate was more closely related to 1996 Romanian and 1999 Russian isolates.
Emerg Infect Dis 8(5) 2002
medscape.com/viewarticle/432548?srcmp=id-062102

PARACHLAMYDIACEAE: POTENTIAL EMERGING PATHOGENS
Some of these Chlamydia-like endosymbionts could cause pneumonia.
Emerg Infect Dis 8(6) 2002
medscape.com/viewarticle/434407?srcmp=id-062102

DEER MEAT AS THE SOURCE FOR A SPORADIC CASE OF ESCHERICHIA COLI O157:H7 INFECTION, CONNECTICUT
Hunters need to know how to safely handle and process venison.
Emerg Infect Dis 8(5) 2002
medscape.com/viewarticle/432547?srcmp=id-062102

EPIDEMIOLOGIC DIFFERENCES BETWEEN CYCLOSPORIASIS AND CRYPTOSPORIDIOSIS IN PERUVIAN CHILDREN
Cryptosporidiosis was more frequent in houses without a toilet; cyclosporiasis was associated with domestic animals.
Emerg Infect Dis 8(6) 2002
medscape.com/viewarticle/434411?srcmp=id-062102

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HAJJ-RELATED NEISSERIA MENINGITIDIS SEROGROUP W135 IN MAURITIUS
Epidemiologic case reports investigate transmission routes
for rare new cases of meningococcal disease in Mauritius. Review
"Hajj-Related Neisseria meningitidis Serogroup W135 in
Mauritius," featured in the Sepsis Resource Center:
medscape.com/mp/rc/usmd/sepsis

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___________________________________ NEWS ______________________________

-- SMALLPOX --

CDC PANEL RECOMMENDS SMALLPOX VACCINE FOR SMALL NUMBER OF AMERICANS
A federal advisory committee on Thursday recommended against immunizing the general American public against smallpox, saying that the vaccine's risks far outweigh the likelihood of a terrorist attack with the virus.
Reuters Health Information 2002
medscape.com/viewarticle/437006?srcmp=id-062102

SMALLPOX VACCINATION OF HEALTHCARE PERSONNEL DEBATED
With federal health authorities preparing this week to set policy for using hundreds of millions of doses of soon-to-be stockpiled smallpox vaccine, physicians and other healthcare workers are recommending a broad definition of who qualifies for early vaccination as 'medical first responders.'
Reuters Health Information 2002
medscape.com/viewarticle/436752?srcmp=id-062102

SOVIET SMALLPOX REPORT PROBABLY WILL NOT AFFECT US VACCINATION POLICY
A report detailing the possible environmental release of weaponized smallpox in the Soviet Union in 1971 has so far done little to make US officials rethink this country's evolving strategy for countering a smallpox attack.
Reuters Health Information 2002
medscape.com/viewarticle/436753?srcmp=id-062102

-- INFLUENZA --

GENETIC REASSORTMENT OF 'BIRD FLU' VIRUSES COULD RESULT IN HUMAN OUTBREAK
Continuing evolution of avian influenza viruses could result in a human pandemic far worse than the outbreak of 'bird flu' in Hong Kong in 1997, investigators report in the June 25th issue of the Proceedings of the National Academy of Sciences.
Reuters Health Information 2002
medscape.com/viewarticle/436856?srcmp=id-062102

-- ENTEROVIRUSES --

HAND, FOOT, AND MOUTH DISEASE STRIKES HONG KONG PRESCHOOLERS
More than 30 children in a Hong Kong kindergarten have contracted hand, foot and mouth disease, a Health Department spokesman said on Tuesday.
Reuters Health Information 2002
medscape.com/viewarticle/436849?srcmp=id-062102

-- SKIN INFECTIONS --

NO COMMON CAUSE FOUND FOR RASHES SEEN IN US CHILDREN
No common source has been identified for the rashes reported among US schoolchildren in recent months, researchers at the US Centers for Disease Control and Prevention (CDC) announced Thursday.
Reuters Health Information 2002
medscape.com/viewarticle/437012?srcmp=id-062102

-- GI TRACT --

LACTOBACILLI AMELIORATE ACUTE CHILDHOOD DIARRHEA WHEN ADMINISTERED EARLY
Oral bacteriotherapy with Lactobacillus rhamnosus and L. reuteri reduces the duration of diarrhea in children with mild gastroenteritis and in those with more severe disease requiring hospitalization, Danish researchers report.
Reuters Health Information 2002
medscape.com/viewarticle/436929?srcmp=id-062102

TYPHOID CARRIER STATE TRACED TO SINGLE POINT MUTATION IN SALMONELLA TYPHIMURIUM
A single point mutation in Salmonella typhimurium may determine why one person infected with typhoid fever can fall ill and die, while another, such as Mary Mallon, known to history as 'Typhoid Mary,' can remain healthy for years, but infect others.
Reuters Health Information 2002
medscape.com/viewarticle/437014?srcmp=id-062102

-- VACCINES & IMMUNIZATION --

CDC LIFTS RESTRICTION ON TETANUS, DIPHTHERIA BOOSTERS AFTER AVENTIS BUILDS UP SUPPLY
Aventis Pasteur, the vaccine arm of France's Aventis SA, said on Thursday that it has produced a large enough supply of its tetanus and diphtheria (Td) vaccine for the US CDC to lift its year-long deferral on Td boosters.
Reuters Health Information 2002
medscape.com/viewarticle/437016?srcmp=id-062102

-- CJD/BSE --

PSYCHIATRIC SYMPTOMS WITH NEUROLOGICAL FEATURES SUGGEST VARIANT CJD
Variant Creutzfeldt-Jakob disease (CJD) should be suspected when patients develop both psychiatric and neurologic features within 4 months after the onset neurologic symptoms, British investigators report in the British Medical Journal for June 22.
Reuters Health Information 2002
medscape.com/viewarticle/437018?srcmp=id-062102

-- PROTOZOAL INFECTIONS --

FUMAGILLIN EFFECTIVE IN INTESTINAL MICROSPORIDIOSIS
It may be the best therapy for immunocompromised patients.
Medscape Medical News 2002
medscape.com/viewarticle/436925?srcmp=id-062102

-- HEPATITIS --

BRITAIN URGED TO COMPENSATE HEMOPHILIACS
The British government was urged to make retribution to people who acquired hepatitis C through tainted blood products.
Reuters Health Information 2002
medscape.com/viewarticle/436872?srcmp=id-062102

-- PEDIATRIC ID --

ANTIBIOTIC PRESCRIPTION RATES FOR US CHILDREN HAVE FALLEN
In the past decade, antibiotic prescription rates for children and adolescents in the US have decreased significantly, according to a report published in the June 19th issue of JAMA.
Reuters Health Information 2002
medscape.com/viewarticle/436847?srcmp=id-062102

-- HIV/AIDS - CLINICAL --

INFANTS OF HIV-INFECTED MOTHERS EXHIBIT PERSISTENT CARDIAC DYSFUNCTION
Infants born to mothers infected with HIV exhibit left ventricular (LV) dysfunction regardless of their HIV status, according to results of a prospective study that appear in the early online edition of The Lancet for June 18.
Reuters Health Information 2002
medscape.com/viewarticle/436793?srcmp=id-062102

PAIN LINKED WITH HIGHER MORTALITY IN HIV-INFECTED CHILDREN ON HAART
Pain is an independent indicator of mortality in children with HIV disease, according to members of the Pediatric AIDS Clinical Trials Group's Late Outcomes Study.
Reuters Health Information 2002
medscape.com/viewarticle/436934?srcmp=id-062102

ETANERCEPT BLUNTS PROINFLAMMATORY EFFECTS OF IL-2 THERAPY IN HIV-INFECTED PATIENTS
HIV-infected patients starting recombinant interleukin-2 (rhIL-2) therapy may benefit from pretreatment with the tumor necrosis factor-alpha (TNF-a) blocker, etanercept (Enbrel; Immunex, Seattle), results of a pilot study suggest.
Reuters Health Information 2002
medscape.com/viewarticle/436994?srcmp=id-062102

BONE MARROW FAT REDUCED IN HIV-INFECTED MEN
Certain HIV-positive men show reduced intravertebral bone marrow fat, researchers from Massachusetts General Hospital in Boston report in the June 14th issue of AIDS.
Reuters Health Information 2002
medscape.com/viewarticle/436782?srcmp=id-062102

TENOFOVIR EFFECTIVE AGAINST WIDE RANGE OF RESISTANT HIV-1 STRAINS
In HIV-infected patients with a wide range of genotypic resistance patterns, the addition of the acyclic nucleoside analogue tenofovir DF to their current regimen provides a significant and lasting reduction in viral loads, according to a recent report.
Reuters Health Information 2002
medscape.com/viewarticle/436860?srcmp=id-062102

VIRAL SPREAD INTO LYMPH NODES MAY LEAD TO HIV-SPECIFIC B-CELL ACTIVATION
Activation of B cells, a hallmark of HIV infection, may be sustained by the spread of virus into the lymph node germinal centers, according to a report in the June 14th issue of AIDS.
Reuters Health Information 2002
medscape.com/viewarticle/436949?srcmp=id-062102

-- HIV/AIDS - GLOBAL/POLITICAL --

EUROPEAN COMMISSION PUBLISHES HIV VERTICAL TRANSMISSION GUIDELINES
New guidelines for preventing the spread of HIV from infected women to their infants were released by the European Commission on Thursday, continuing the international focus on vertical transmission that has been stressed recently by US president George Bush and the United Nations.
Reuters Health Information 2002
medscape.com/viewarticle/436985?srcmp=id-062102

BUSH ANNOUNCES GLOBAL PLAN TO FIGHT HIV SPREAD
President Bush announced a $500 million program on Wednesday to cut the spread of HIV and AIDS from infected mothers to their infants in African and Caribbean nations hardest hit by the global AIDS epidemic.
Reuters Health Information 2002
medscape.com/viewarticle/436937?srcmp=id-062102

US OFFICIALS SEEK AIDS FUNDING FOR MYANMAR
US officials Wednesday asked Congress for $1 million to fight HIV/AIDS in Myanmar despite strict US sanctions on the military-led country, saying it was now the center of the disease in the region.
Reuters Health Information 2002
medscape.com/viewarticle/437017?srcmp=id-062102

-- OTHER NEWS --

AMA APPROVES WIDE REORGANIZATION PLAN
After hours of debate, the American Medical Association approved a plan to overhaul the AMA by changing it from a membership organization to an umbrella organization, similar to the United Nations.
Reuters Health Information 2002
medscape.com/viewarticle/436998?srcmp=id-062102

EUROPE PROPOSES NEW HUMAN TISSUE SAFETY RULES
The European Commission proposed on Wednesday that the region adopt for the first time unified safety and quality standards for human tissue and cells used in medicine.
Reuters Health Information 2002
medscape.com/viewarticle/436941?srcmp=id-062102

FRIST WILL NOT HEAD NEW US HOMELAND SECURITY AGENCY
Sen. Bill Frist, R-Tenn., said Wednesday that he would not accept an offer to become head of the new Department of Homeland Security being proposed by the White House.
Reuters Health Information 2002
medscape.com/viewarticle/436959?srcmp=id-062102

NUCLEAR SCAN IDENTIFIES 100% OF INFECTION, INFLAMMATION SITES
Depreotide detects sites in 3 hours, much faster than WBC scan.
Medscape Medical News 2002
medscape.com/viewarticle/436828?srcmp=id-062102

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Vaccination News Home Page

ALL INFORMATION, DATA, AND MATERIAL CONTAINED, PRESENTED, OR PROVIDED HERE IS FOR GENERAL INFORMATION PURPOSES ONLY AND IS NOT TO BE CONSTRUED AS REFLECTING THE KNOWLEDGE OR OPINIONS OF THE PUBLISHER, AND IS NOT TO BE CONSTRUED OR INTENDED AS PROVIDING MEDICAL OR LEGAL ADVICE.  THE DECISION WHETHER OR NOT TO VACCINATE IS AN IMPORTANT AND COMPLEX ISSUE AND SHOULD BE MADE BY YOU, AND YOU ALONE, IN CONSULTATION WITH YOUR HEALTH CARE PROVIDER.