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Archive Number 20020531.4375
Published Date 31-MAY-2002
Subject PRO/EDR> Child deaths after vaccination - Cuba
CHILD DEATHS AFTER VACCINATION - CUBA
*************************************
A ProMED-mail post
<http://www.promedmail.org>
ProMED-mail is a program of the
International Society for Infectious Diseases
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Date: Thurs 30 May 2002 10:28 PM EDT
From: ProMED-mail <promed@promedmail.org>
Source: AP Online [edited]


Cuba suspends measles vaccination
---------------------------------
HAVANA (AP): Cuba announced on Thursday that its measles vaccination 
program had been suspended after an "uncommon accident" with imported 
vaccine dosages that left 3 children dead and 42 others sick. The 3 
children died last week after receiving injections from "apparently 
contaminated" vials filled with the anti-measles vaccine manufactured in 
India. "After the accident was known, it was decided a week ago to stop the 
vaccinations underway across the country," the government said in a 
communique carried in the Communist Party daily Granma. Cuba said it had 
formed a commission to investigate.

The communique said the vaccines had been certified by and acquired through 
the World Health Organization. It provided no other details on Cuba's 
acquisition of the vaccines, nor where in Cuba the children had died.

"Through the Health Ministry's monitoring systems, an uncommon accident was 
detected on 22 May 2002 in several vaccinated children," the communique said.

Cuba said that during this year's anti-measles campaign more than 750 000 
other children between 4 and 9 years old have been vaccinated without 
adverse reactions. Cuba, which is proud of its world renowned childhood 
health care programs, has had an extensive vaccination program for its 
children since the 1970s.

Cuba produces some vaccines, such as for meningitis B and hepatitis B. But 
it does not manufacture vaccines for childhood diseases such as measles, 
said Dr Pedro Lopez Saura, clinical trials director for Cuba's Center of 
Genetic Engineering and Biotechnology.

-- 
ProMED-mail
<promed@promedmail.org>

[Last year a cluster of deaths was associated with measles vaccination in 
Algeria (see ProMED-mail postings listed below). Investigation revealed 
that an inappropriate diluent was used to reconstitute the lyophilized 
vaccine, and involved one vial of vaccine used in the country. The above 
report mentions use of "contaminated vaccine" with 3 deaths and 42 
additional ill children. As the newswire goes on to mention that more than 
750 000 other children were vaccinated with measles vaccine without any 
untoward effects, one wonders if this incident might be due to a similar 
cause. There is no mention of the geographic distribution of the cases, nor 
of the clinical syndromes involved. If all affected children came from the 
same vaccination center it would more strongly suggest a localized event 
rather than a broader vaccine supply event.

ProMED-mail would greatly appreciate more information on this episode from 
official sources, rather than rely upon speculation and information from 
the lay press. - Mod.MPP]

[see also:
Infant deaths after vaccination - Algeria (Mascara) (02) 20011226.3115
Infant deaths after vaccination - Algeria (Mascara)      20011224.3107]

....................mpp/pg/sh

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