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Vaccinating Against Varicella at 9 Months of Age
So, because a 2 dose schedule is routinely
recommended at age 12, it should be okay at 12 months SM
We have just encountered a patient who was inadvertently
vaccinated against varicella at 9 months of age. Should we repeat the vaccine
at 1 year of age?
Dr. D. Katz
Response
from Samuel
L. Katz, MD, 06/21/01
Varicella vaccine was licensed for routine use in the United States in March
1995 and has been recommended for use in healthy varicella-susceptible persons
over the age of 1 year by the Advisory Committee on Immunization Practice of
the Centers for Disease Control (ACIP/CDC), the American Academy of Pediatrics
(AAP), and the American Academy of Family Practitioners (AAFP).[1-3]
Administration of vaccine prior to 12 months of age is inadvisable because
of the persistence of maternal transplacental antibody which may block
replication of the vaccine virus. It is doubtful that varicella vaccine would
be successful at the early age of 9 months. The vaccine should be repeated at
or shortly after the first birthday when its immunogenicity is assured. The
extra dose should have no ill effects and should be safe. Indeed, for
youngsters over 12 years of age, a 2-dose schedule is recommended routinely.
References
Centers for Disease Control
and Prevention. Prevention of varicella. Updated Recommendations of the
Advisory Committee on Immunization Practices (ACIP). MMWR Morb Mortal Wkly
Rep. 1999;48:1-5.
Vazquez N, LaRussa PS,
Gershon AA, Steinberg SP, Freudigman K, Shapiro ED. The effectiveness of
the varicella vaccine in clinical practice. N Engl J Med.
2001;344:955-960.
Committee on Infectious
Diseases. Varicella vaccine update. Pediatrics. 2000;105:136-141.
ALL INFORMATION, DATA, AND MATERIAL CONTAINED, PRESENTED, OR PROVIDED HERE
IS FOR GENERAL INFORMATION PURPOSES ONLY AND IS NOT TO BE CONSTRUED AS
REFLECTING THE KNOWLEDGE OR OPINIONS OF THE PUBLISHER, AND IS NOT TO BE
CONSTRUED OR INTENDED AS PROVIDING MEDICAL OR LEGAL ADVICE. THE DECISION
WHETHER OR NOT TO VACCINATE IS AN IMPORTANT AND COMPLEX ISSUE AND SHOULD BE
MADE BY YOU, AND YOU ALONE, IN CONSULTATION WITH YOUR HEALTH CARE PROVIDER.
"A foolish faith in authority is the worst enemy of truth."
-- Albert Einstein, letter to a friend, 1901
"I know of no safe depository of the ultimate powers of the society but the people themselves, and if we think them not enlightened enough to exercise control with a wholesome discretion, the remedy is not to take it from them, but to inform their discretion by education."
-- Thomas Jefferson, letter to William C. Jarvis, September 28, 1820
"What's the point of vaccination if it doesn't protect you from the unvaccinated?"
-- Sandy Gottstein
"Who gets to decide what the greater good is and how many will be sacrificed to it?"