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Monday June 25 10:39 AM ET

Leading Malaria Vaccine Groups Join Forces

By Will Dunham

WASHINGTON (Reuters) - Three major players in the quest to develop vaccines for malaria have joined forces in a bid to speed the fight against a tropical disease that has plagued humanity for eons and kills 2 million people annually, officials said on Friday.

The private Seattle-based Program for Appropriate Technology in Health (PATH) has formed an alliance with the European Commission (news - web sites)'s malaria vaccine program and a similar program at the US Agency for International Development (USAID), the organizations said in a statement.

PATH's effort is boosted by a $50 million grant from the foundation created by computer software mogul Bill Gates (news - web sites).

Malaria is a parasitic infection transmitted by the bite of a mosquito. Most of those who die are children in Africa, but it also claims victims in parts of Asia and Latin America. Between 300 million and 500 million people are infected annually.

Dr. Regina Rabinovich, director of PATH's Malaria Vaccine Initiative, said the alliance would allow the pooling of information and cut down on unnecessary duplication of efforts. She expressed optimism that the alliance would hasten the development of vaccines and predicted one would be licensed in ''probably a decade.''

``It hasn't created that sense of urgency that can be associated with a newly emerging disease, but it's not something that we, with the scientific tools that exist today, can ethically afford to ignore,'' Rabinovich said in an interview. ''The tools are at hand. We can make this vaccine.''

The groups said they would work together to facilitate the testing and manufacture of vaccine candidates and ensure their accessibility and affordability in impoverished nations. A number of vaccine candidates are in the developmental pipeline, but the one farthest along does not provide long-lasting protection.

Malaria is known for developing resistance to current drug treatments. Experts said only an effective vaccine would enable public health officials to contain the disease.

Rabinovich said the three groups together will spend about $20 million annually on vaccine development. She said the US government's National Institutes of Health (news - web sites) also collaborates with the groups, providing another $28 million annually to the cause.

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