http://news.bbc.co.uk/hi/english/health/newsid_636000/636547.stm
Wednesday, 9 February, 2000, 19:03 GMT
Bacteria may be added to tampons
Women’s sanitary products could be fortified with live
bacteria to help reduce the risk of urinary tract and gynaecological
infections, scientists have said.
Live bacteria are often added to dairy products such as
yoghurt to aid digestion.
Now New Scientist magazine reports that Swedish scientists
think the same approach could be applied to women’s hygiene products such as
tampons and panty liners.
They think such an approach could help to kill off
bacteria that can cause infections of the urinary tract and vagina - some of
which are suspected of causing premature births and of infecting newborn
babies.
Eva Grahn Hakansson and her colleagues at the University
of Umea in Sweden have discovered a strain of bacteria which they hope can be
impregnated into such products to displace the harmful bugs.
The idea has been patented by SCA Hygiene Products of
Gothenburg, a major supplier of sanitary products.
Company director Per Martinson said: “We are at a very
early stage, doing basic research, and hoping it will be commercialised some
time.”
The bacteria in question is a previously unknown strain of
Lactobacillus plantarum.
It was originally isolated from the vagina of a healthy
pregnant woman.
In lab tests, Dr Hakansson and her colleagues demonstrated
that the L. plantarum strain completely
inhibits growth of several bacteria known to cause gynaecological and obstetric
problems.
They include gut-dwelling bacteria such as Klebsiella
species and Escherichia coli, which cause vaginal and urinary tract infections
in women.
It also combats group B streptococci, which are notorious
for causing serious infections in newborn babies as they pass through the
vagina.
Staphylococci and yeasts such as Candida albicans, which
causes thrush, were also kept at bay.
The new strain of L. plantarum does not affect harmless
bacteria - such as other strains of lactobacilli - which normally dominate in
the vagina.
The lactic and acetic acids these bacteria produce help to
keep harmful bugs at bay.
In tests on female volunteers, the Umea team showed that
L. plantarum is capable of colonising common sites of infection, such as the
urethral opening and the perineum.
The patent also covers use of the bacterium in ointments,
creams and lotions for treating gynaecological conditions.
The team found that products impregnated with L. plantarum
have a shelf-life of up to a year.
However, these products will have to be validated by
lengthy clinical trials before they can go on sale.
Dr Glenn Gibson, a food researcher at the University of
Reading, is developing strains of Bifidobacterium bifidum which combat harmful
gut bacteria.
He said: “I’ve never come across the use of probiotics in
panties before, but nevertheless, these organisms are pretty good inhibitors of
pathogens.”
Dr Sally Hope, a GP in Oxford and chair of the primary
care gynaecology group, said that women with infections such as thrush were
already recommended by doctors to eat yoghurt containing live bacteria, and in
some cases to insert yoghurt into the vagina.
She said: “The vagina naturally contains beneficial
bacteria, but the problem with modern medicine is that antibiotics wipe out all
bugs, good and bad.”
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