Medical journals are often accused of being remote from the real world. They
present the results of trials conducted on highlyselected patients
in ideal circumstances. They view the worldfrom London, Boston, or
Chicago unaware that in Peioria or Harrogatepatients don't turn up,
won't comply with treatments, and scoffat "patient centredness" and
that the local hospitals are fallingdown and run by people who until
yesterday were running sewageplants. Well, this issue has a whiffeven
a stinkfrom the realworld.
The BMJ has published many studies suggesting that serum screening for
Down's syndrome in pregnant women is more effectivethan screening
based on age, but an audit of over 150 000 deliveriessuggests that
may not be true (p
15). The models in support ofserum screening assumed that 5% of
mothers were over 35. In fact,15% are. An editorial considers why
eradication of Helicobacterpylori often fails in ordinary
practice (p
3).
The answer seemsto be growing antibiotic resistance. Antibiotics
have traditionallybeen prescribed for children with acute otitis
media, but systematicreviews suggest that there is little benefit (p
22). But it'shard in the real world to suggest to parents that
antibioticsare not indicated. Now a further review suggests that it
may beworth giving them to children who have high temperatures or
whoare vomitingalthough
even then it may be worth waiting for 24to 48hours.
Selected patients with stroke can probably be helped with thrombolytic drugs
if seen quickly and if they undergo computedtomography. A
multicentre study from Britain shows how hard thisis to achieve in
the real world. Only 37% of patients arrive athospital within three
hours of their stroke. Computed tomographywas requested within three
hours of arrival in hospital in 22%of patients but undertaken in
only 8%. Ideally, all patients withserious illness would be admitted
quickly to hospitals with thefull range of services. But many people
live a long way from suchhospitals, and, says a report from the
Royal College of Physicians,patients in at least 30 "isolated"
hospitals are at increasedrisk because of the lack of intensive care
(p
8). The realpolitikof reconfiguring such hospitals is terrifyingat
least topoliticians.
Any notion of the real world is philosophically questionable (why, for
example, are my dreams less real than what I do duringthe day?) and
certainly relative. In the United Statesunlikein the vast majority of countriesthey
have thought it acceptableto execute mentally retarded prisoners.
Now the Supreme Courthas ruled it unacceptable (p
9). But consider the real world ofSierra Leone described in the
obituary of Arthur Osman FarquarStuart (p
47), the "people's doctor" of Sierra Leone. "What arelief," he
wrote, "to be free of the soldiers who would cut apregnant woman's
belly open to settle a bet whether she was carryinga baby boy or
babygirl."
PRIMARY CARE Predictors of poor outcome and benefits from antibiotics in children
with acute otitis media: pragmatic randomised trial
Commentary: research directions for treatment for acute otitis media.
Paul Little, Clare Gould, Michael Moore, Greg Warner, Joan Dunleavey, Ian
Williamson, Chris Del Mar, and Jenny Doust
BMJ 2002 325: 22. [Abstract][Abridged text][Full text]
OBITUARIES Arthur Osman Farquhar Stuart.
Hugh T Fay and E Luke I B Amara
BMJ 2002 325: 47.
[Full text]
NEWS ROUNDUP Acutely ill patients at risk in 30 "isolated" hospitals.
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YOUR HEALTH CARE PROVIDER.
"A foolish faith in authority is the worst enemy of truth."
-- Albert Einstein, letter to a friend, 1901
"I know of no safe depository of the ultimate powers of the society but the people themselves, and if we think them not enlightened enough to exercise control with a wholesome discretion, the remedy is not to take it from them, but to inform their discretion by education."
-- Thomas Jefferson, letter to William C. Jarvis, September 28, 1820
"What's the point of vaccination if it doesn't protect you from the unvaccinated?"
-- Sandy Gottstein
"Who gets to decide what the greater good is and how many will be sacrificed to it?"