The number of babies born with certain birth defects has soared over the
last five years, a medical charity has warned.
The Birth Defects Foundation (BDF) suggests certain types of
abnormalities have increased by up to 50% over that time.
The BDF estimates one in 16 of all births results in neonatal
abnormalities such as cleft palates of malformations of the hands and
feet, around six times higher than official figures report.
The charity says this could be because they count all birth defects,
rather than just the most severe, some defects may not become apparent for
some time, and because official statistics rely on a voluntary system of
reporting.

If you want to give your child the best chance in life then you can

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Sheila Brown, Birth Defects Foundation
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Figures from the Office for National
Statistics show there were 7,284 children born in 2000 notified to the
National Congenital Abnormality System. But the BDF said this "seriously
underestimated" the true situation.
The charity is launching a campaign on Monday to spell out a five-point
plan to give mothers a better chance of having a healthy baby.
The plan will cover family medical history, taking folic acid
supplements, reducing alcohol, stopping smoking and eating a balanced
diet.
Oestrogen link
The occurrence of some birth defects has declined, but the BDF has
shown a sharp rise in three specific defects; cleft lip or palate,
gastroschisis (abnormality of the abdominal wall) and hypospadias (a
condition affecting boys in which the opening of the penis is situated on
the underside of the shaft).
Why there has been a rise in certain types of defects is not clear, but
long-term use of recreational drugs by young mothers and an increase in
oestrogen-like substances in diets are possible explanations.
Research for the BDF suggests the incidence of cleft lip or palate,
which can require a number of operations to repair, had increased from 5.8
cases per 10,000 births in 1995 to 9.2 cases in 1999.
Hypospadias has risen from 7.5 cases per 10,000 to 8.5.
Gastroschisis, a weakness in the abdominal wall that leaves the
intestines protruding at birth, has risen from 1.3 to 1.9.
The condition has been rising in both the UK and the US and is five
times more common in teenage mothers than other age groups.
Professor Michael Patton, medical director of the BDF and head of
medical genetics at St George's Hospital, Tooting, London, told BBC News
Online said there were theories, though no proof, for why these relatively
rare conditions were being seen more frequently.
He said: "With hypospadias, it is just possible there could be an
environmental effect, possibly with an oestrogen-like effect in the
environment. That would be a potential theory, but we haven't done a study
that proves it."
Other experts have made a link between hypospadias and the fertility
technique intracytoplasmic sperm injection.
Professor Patton added: "Gastroschisis has always been a relatively
rare abnormality. But there seems to have been an increase amongst younger
mothers in urban areas.
Practical planning
"We don't have any positive proof, but there has been a suggestion that
the wider use of a mixture of recreational drugs could be behind that
increase."
One success story highlighted by Professor Patton is the decrease in
incidence of spina bifida, which has fallen by two thirds in women at high
risk because they have a family history of the condition.
Folic acid, known to help prevent spina bifida and other neural tube
defects (NTDs), us now given to all pregnant women.
Sheila Brown, chief executive of the BDF, told BBC News Online it was
important prospective parents were aware of family medical history of
conditions such as congenital heart malformation, so they could make
practical plans like having the baby in hospital rather than at home.
She added: "We're not saying that all birth defects are caused by
drinking, smoking or street drugs. But we are saying, if you want to give
your child the best chance in life, then you can by following the points
in the plan."