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New Approaches to Autism
Television News Service/Medical Breakthroughs
© Ivanhoe Broadcast News, Inc. July 2001


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(Ivanhoe Newswire) — The developmental disorder autism is characterized by three core symptoms. Traditionally doctors use one drug to treat all of them. Now researchers in New York are taking a different approach they hope will help more children.

Like every mother, Jane Neill-Hancock wants the best for her daughter. Her wishes sound simple. "I'd like to see her have a friend and even know what friendship is," she says.

Shinae is autistic. The older she gets, the more severe her symptoms. Neill-Hancock says, "She becomes very focused on something, and she can't give it up. She has a lot of trouble with frustration and with anger."

Experimental diets and numerous drugs have not shown the improvements Neill-Hancock anticipated. Now, she's hoping the antidepressant Prozac will do the trick.

Psychiatrist Eric Hollander, M.D., of Mt. Sinai School of Medicine in New York, N.Y., has seen around 50 percent of children improve their functioning with Prozac but says it's not the answer for everyone.

"Our approach in terms of treating individuals with autism is to break the disorder down into its different symptom domains and then address those different symptom domains with appropriate medication," says Dr. Hollander.

The anti-seizure medication Depakote is under study to treat aggression. For cognitive difficulties, the psychosis drug olanzapine is expected to bring improvements.

Dr. Hollander says, "Just modifying those key target symptoms can have a dramatic impact in terms of their quality of life."

Neill-Hancock learned not to hope for a dramatic change, subtle improvements will do. She says, "[I hope it] will be easier for her to deal with things and maybe to focus a little bit more."

Her ultimate goal is to one day see Shinae able to cope with others around her.

All the drugs in the study have been tested for safety in children and are approved for use by children over the age of 5.

If you would like more information, please contact:

Eric Hollander, M.D.

Mt. Sinai School of Medicine

One Gustave Levy Place

Box 1230

New York, NY 10029-6574

(212) 241-3623

Prior Reports:
Curbing Autistic Aggression December 2000
Antibiotics for Autism December 2000
Overcoming Autism March 1998
Autism/Manic Depression December 1996
Electronic Ear November 1996
Birthday Revelations of Autism July 1996

 

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