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ReutersTop Science and Health News


 

MMR Vaccination Linked to Bleeding Disease
Reuters
Feb 22 2001 10:00AM

LONDON (Reuters) - The triple measles, mumps and rubella vaccine (MMR) can cause a rash-like bleeding disease in young children but doctors say it is not dangerous and should not deter parents from having their children vaccinated.

The illness, idiopathic thrombocytopenic purpura (ITP), is an auto-immune disease in which the platelets, or cells that make blood sticky, are destroyed, causing bleeding under the skin. It occurs in about one in 10,000 people.

Doctors are keen to dispel recent allegations of a link between the triple jab and development of autism as well as to counter accusations that they have not been honest about the risks of the vaccination.

Dr. Brent Taylor said the ITP research shows that scientists are open and frank about the effects of MMR and have nothing to hide.

"We're looking carefully for adverse effects and we're very keen to report them to avoid nonsense about a conspiracy of silence," he added.

The link between the MMR vaccine and ITP has been known for more than a decade. Research conducted at Britain's Public Health Laboratory Service (PHLS) and Royal Free Hospital in London shows that about one in every 22,300 MMR vaccinations could result in a child being admitted to hospital for ITP.

"The reason for doing the study was because we could look at much bigger numbers and be confident in terms of the risk," Taylor said in a telephone interview.

The majority of cases of ITP in children will have nothing to do with the vaccination, according to Dr. Elizabeth Miller, of the PHLS, who led the research team. Even in cases linked to MMR the disease is rarely dangerous and is usually easily treated, she said.

LESS SERIOUS THAN GERMAN MEASLES

The scientists, whose research is published in the Archives of Disease in Childhood, said parents should vaccinate their children because ITP is much less serious than German measles.

"We urge parents to protect their children against measles, mumps and rubella with the MMR vaccine," said Miller.

"The risks associated with ITP are small when compared to those of the disease which this vaccine is designed to prevent."

The link between the triple jab, which is given to children when they are 18 months to two years old, and ITP follows earlier fears that the MMR vaccination could cause autism and bowel disease. Concerns about the autism link have led to a drop in the number of children being vaccinated and fears about a resurgence of German measles.

The researchers established the link with ITP by analyzing hospital admissions for the disease between October 1991 and September 1994. The data included records of children who developed the illness within six weeks of an MMR vaccination.

ITP is usually caused by a viral infection and is most common in children under three years old.
RTR/SCIENCE-HEALTH-MMR-DC/
Copyright © 2001 Reuters Limited. All rights reserved. Republication or redistribution of Reuters content, including by framing or similiar means, is expressly prohibited without the prior written consent of Reuters. Reuters shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon. All active hyperlinks have been inserted by AOL Anywhere.

 

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