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MedPulse is a weekly index of key news and features on Medscape's

specialty sites compiled by Medscape's Editors.

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___________________ NEW FEATURE ARTICLES THIS WEEK ____________________

 

 

--DEPARTMENTS--

CLINICAL CASES FROM JOHNS HOPKINS NEUROLOGY - CASE 10: A 5-YEAR-OLD BOY

WITH SUDDEN ONSET OF VOMITING AND INABILITY TO WALK

What could have caused sudden ataxia in this kindergartner?

Medscape Neurology, 2002

http://pediatrics.medscape.com/47214.rhtml?srcmp=ped-011802

<a href="http://pediatrics.medscape.com/47214.rhtml?srcmp=ped-011802">

Read it Here</a>

 

BOOK REVIEW - MISCONCEPTIONS: TRUTH, LIES, AND THE UNEXPECTED ON THE

JOURNEY TO MOTHERHOOD

Naomi Wolf condemns the entire field of obstetrics in her latest book.

MedGenMed, January 15, 2002

http://pediatrics.medscape.com/47201.rhtml?srcmp=ped-011802

<a href="http://pediatrics.medscape.com/47201.rhtml?srcmp=ped-011802">

Read it Here</a>

 

JOURNAL SCAN - PEDIATRICS 5(1)

Journal Scan is the clinician's guide to the latest clinical research

findings in Pediatrics, The Journal of Pediatrics, Archives of

Pediatrics and Adolescent Medicine, Pediatric Infectious Disease

Journal.

http://pediatrics.medscape.com/47199.rhtml?srcmp=ped-011802

<a href="http://pediatrics.medscape.com/47199.rhtml?srcmp=ped-011802">

Read it Here</a>

 

 

--UPDATE ON VACCINES--

THIMEROSAL AND VACCINES

Why is mercury in vaccines of sudden concern in the United States?

http://pediatrics.medscape.com/47200.rhtml?srcmp=ped-011802

<a href="http://pediatrics.medscape.com/47200.rhtml?srcmp=ped-011802">

Read it Here</a>

 

THE SECOND MMR VACCINATION

If a child receives a second measles-mumps-rubella (MMR) vaccine before

the fourth birthday, should another dose be given after the child turns

4?

http://pediatrics.medscape.com/47205.rhtml?srcmp=ped-011802

<a href="http://pediatrics.medscape.com/47205.rhtml?srcmp=ped-011802">

Read it Here</a>

 

MINIMUM INTERVALS BETWEEN VACCINE ADMINISTRATIONS

What should be the minimum interval between 2 nonlive vaccine

administrations? What about 2 live vaccines?

http://pediatrics.medscape.com/47223.rhtml?srcmp=ped-011802

<a href="http://pediatrics.medscape.com/47223.rhtml?srcmp=ped-011802">

Read it Here</a>

 

CURRENT SMALLPOX VACCINE GUIDELINES

Given the current political climate, what is the current guideline for

children regarding smallpox vaccine?

http://pediatrics.medscape.com/47224.rhtml?srcmp=ped-011802

<a href="http://pediatrics.medscape.com/47224.rhtml?srcmp=ped-011802">

Read it Here</a>

 

HEPATITIS A VACCINE AND HEMOPHILIACS

What is the rationale for the hepatitis A vaccine recommendation for

hemophiliacs?

http://pediatrics.medscape.com/47225.rhtml?srcmp=ped-011802

<a href="http://pediatrics.medscape.com/47225.rhtml?srcmp=ped-011802">

Read it Here</a>

 

 

--PROMOTING INFANT AND CHILD HEALTH--

VITAMIN K FOR THE PREVENTION OF BLEEDING IN NEWBORNS

The prevention of vitamin K-deficiency bleeding in infancy remains a

worldwide concern.

Pediatric Pharmacotherapy (7)10, 2001

http://pediatrics.medscape.com/47232.rhtml?srcmp=ped-011802

<a href="http://pediatrics.medscape.com/47232.rhtml?srcmp=ped-011802">

Read it Here</a>

 

ETIOPATHOGENESIS OF BILIARY ATRESIA

Biliary atresia, a progressive sclerosis of the extrahepatic biliary

tree that occurs only within the first 3 months of life, is one of the

most common causes of neonatal cholestasis and accounts for over half of

children who undergo liver transplantation.

Sem Liver Disease 21(4):517-524, 2001

http://pediatrics.medscape.com/47218.rhtml?srcmp=ped-011802

<a href="http://pediatrics.medscape.com/47218.rhtml?srcmp=ped-011802">

Read it Here</a>

 

ENTERAL METHADONE TO EXPEDITE FENTANYL DISCONTINUATION AND PREVENT

OPIOID ABSTINENCE SYNDROME IN THE PICU

Fentanyl is a synthetic opioid that is widely administered for sedation

and analgesia in critically ill infants and children in the pediatric

intensive care unit (PICU).

Pharmacotherapy 21(12):1566-1573, 2001

http://pediatrics.medscape.com/47243.rhtml?srcmp=ped-011802

<a href="http://pediatrics.medscape.com/47243.rhtml?srcmp=ped-011802">

Read it Here</a>

 

STREPTOCOCCAL TONSILLOPHARYNGITIS: ADVANTAGES OF SHORTER ANTIBIOTIC

COURSES

Poor compliance with standard antibiotic regimens contributes

significantly to treatment failure in acute group A streptococcal (GAS)

respiratory tract infection.

Infect Med 18(11):515-518, 2001

http://pediatrics.medscape.com/47207.rhtml?srcmp=ped-011802

<a href="http://pediatrics.medscape.com/47207.rhtml?srcmp=ped-011802">

Read it Here</a>

 

 

_______________________________________________________________________

___________________________________ NEWS ______________________________

 

 

--PRENATAL TESTING AND THERAPY--

NONINVASIVE SCREENING METHOD COULD ALLOW EARLIER DOWN SYNDROME DETECTION

Ultrasonographic screening applied during the first trimester can

identify 85% of Down syndrome pregnancies.

http://pediatrics.medscape.com/47252.rhtml?srcmp=ped-011802

<a href="http://pediatrics.medscape.com/47252.rhtml?srcmp=ped-011802">

Read it Here</a>

 

IN UTERO SURGERY SHOWS PROMISE IN TREATING SPINA BIFIDA

Preliminary findings suggest that fetal surgery to repair defects from

spina bifida has several beneficial effects.

http://pediatrics.medscape.com/47250.rhtml?srcmp=ped-011802

<a href="http://pediatrics.medscape.com/47250.rhtml?srcmp=ped-011802">

Read it Here</a>

 

 

--NEONATAL DISORDERS--

HOSPITAL STAFF MAY NOT BE WELL VERSED IN RISK FACTORS FOR SIDS

A survey of medical professionals at a children's hospital indicates

inconsistencies in knowledge about risk factors for sudden infant death

syndrome (SIDS).

http://pediatrics.medscape.com/47269.rhtml?srcmp=ped-011802

<a href="http://pediatrics.medscape.com/47269.rhtml?srcmp=ped-011802">

Read it Here</a>

 

COMBINATION TEST SHOWS PROMISE IN EARLY DIAGNOSIS OF NEONATAL SEPSIS

Determination of C-reactive protein levels and interleukin-6 levels

appears to be useful in the early diagnosis of neonatal sepsis.

http://pediatrics.medscape.com/47153.rhtml?srcmp=ped-011802

<a href="http://pediatrics.medscape.com/47153.rhtml?srcmp=ped-011802">

Read it Here</a>

 

 

--CHILD DEVELOPMENT--

MODERATELY PREMATURE BIRTH POSES RISK FOR DEVELOPMENTAL DELAYS

Contrary to current assumptions, being born just 2 to 4 weeks premature

can put a child at risk for minor delays in development.

http://pediatrics.medscape.com/47220.rhtml?srcmp=ped-011802

<a href="http://pediatrics.medscape.com/47220.rhtml?srcmp=ped-011802">

Read it Here</a>

 

DISADVANTAGES ASSOCIATED WITH VERY-LOW-BIRTHWEIGHT CONTINUE INTO

ADULTHOOD

Educational and other disadvantages that have been linked with

very-low-birthweight persist into young adulthood.

http://pediatrics.medscape.com/47164.rhtml?srcmp=ped-011802

<a href="http://pediatrics.medscape.com/47164.rhtml?srcmp=ped-011802">

Read it Here</a>

 

 

--DIABETES ANF OBESITY--

METFORMIN IS SAFE, EFFECTIVE FOR TREATMENT OF TYPE 2 DIABETES IN

PEDIATRIC PATIENTS

The oral antidiabetic agent metformin is as effective and well tolerated

in children as it is in adults.

http://pediatrics.medscape.com/47149.rhtml?srcmp=ped-011802

<a href="http://pediatrics.medscape.com/47149.rhtml?srcmp=ped-011802">

Read it Here</a>

 

TYPE 1 DIABETES IN CHILDREN SEEMS NOT TO AFFECT ACADEMIC LEARNING

Children with type 1 diabetes do not have lower academic performance

compared with their siblings and classmates.

http://pediatrics.medscape.com/47150.rhtml?srcmp=ped-011802

<a href="http://pediatrics.medscape.com/47150.rhtml?srcmp=ped-011802">

Read it Here</a>

 

BREASTFED CHILDREN OF DIABETICS MIGHT BE AT INCREASED RISK OF OBESITY

Among children of diabetic mothers, those who are principally breast-fed

during the first week of life are more likely than those who principally

receive banked breast milk to be overweight or to develop impaired

glucose tolerance by age 2.

http://pediatrics.medscape.com/47255.rhtml?srcmp=ped-011802

<a href="http://pediatrics.medscape.com/47255.rhtml?srcmp=ped-011802">

Read it Here</a>

 

 

--INFECTIOUS DISEASES--

RAPID INFLUENZA DIAGNOSIS IMPROVES MANAGEMENT IN FEBRILE CHILDREN

The rapid diagnosis of influenza virus type A infection in febrile

infants and toddlers presenting to the emergency department appears to

decrease ancillary tests and antibiotic use.

http://pediatrics.medscape.com/47087.rhtml?srcmp=ped-011802

<a href="http://pediatrics.medscape.com/47087.rhtml?srcmp=ped-011802">

Read it Here</a>

 

THYMIC INVOLUTION TIED TO PROGRESSION OF PEDIATRIC HIV INFECTION

Reduced thymic volume in HIV-1 infected children is associated with

rapid disease progression.

http://pediatrics.medscape.com/47089.rhtml?srcmp=ped-011802

<a href="http://pediatrics.medscape.com/47089.rhtml?srcmp=ped-011802">

Read it Here</a>

 

LYME DISEASE INCIDENCE IN US HAS DOUBLED OVER PAST DECADE

The incidence of new cases of Lyme disease has doubled in the US since

1991.

http://pediatrics.medscape.com/47259.rhtml?srcmp=ped-011802

<a href="http://pediatrics.medscape.com/47259.rhtml?srcmp=ped-011802">

Read it Here</a>

 

 

--RESPIRATORY DISORDERS--

ORAL DEXAMETHASONE IS EFFECTIVE IN CHILDREN WITH MILD CROUP

Children with mild croup benefit from a single dose of oral

dexamethasone, more so than from a nebulized dose.

http://pediatrics.medscape.com/47045.rhtml?srcmp=ped-011802

<a href="http://pediatrics.medscape.com/47045.rhtml?srcmp=ped-011802">

Read it Here</a>

 

EPINEPHRINE COMPARABLE TO SALBUTAMOL IN CHILDHOOD ASTHMA

Subcutaneous epinephrine is as effective as nebulized salbutamol

(albuterol) in the treatment of acute asthma in children.

http://pediatrics.medscape.com/47049.rhtml?srcmp=ped-011802

<a href="http://pediatrics.medscape.com/47049.rhtml?srcmp=ped-011802">

Read it Here</a>

 

IPRATROPIUM NO HELP IN PEDIATRIC ASTHMA EXACERBATION

The addition of inhaled ipratropium bromide to standard therapy offers

no advantages to children hospitalized for asthma exacerbation.

http://pediatrics.medscape.com/47147.rhtml?srcmp=ped-011802

<a href="http://pediatrics.medscape.com/47147.rhtml?srcmp=ped-011802">

Read it Here</a>

 

CETIRIZINE PREVENTS ONSET OF ASTHMA IN SOME ATOPIC INFANTS

Cetirizine may delay or prevent asthma in infants with atopic dermatitis

who are sensitized to grass pollen or to house dust mite.

http://pediatrics.medscape.com/47249.rhtml?srcmp=ped-011802

<a href="http://pediatrics.medscape.com/47249.rhtml?srcmp=ped-011802">

Read it Here</a>

 

 

 

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ALL INFORMATION, DATA, AND MATERIAL CONTAINED, PRESENTED, OR PROVIDED HERE IS FOR GENERAL INFORMATION PURPOSES ONLY AND IS NOT TO BE CONSTRUED AS REFLECTING THE KNOWLEDGE OR OPINIONS OF THE PUBLISHER, AND IS NOT TO BE CONSTRUED OR INTENDED AS PROVIDING MEDICAL OR LEGAL ADVICE.  THE DECISION WHETHER OR NOT TO VACCINATE IS AN IMPORTANT AND COMPLEX ISSUE AND SHOULD BE MADE BY YOU, AND YOU ALONE, IN CONSULTATION WITH YOUR HEALTH CARE PROVIDER.