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“Healing Autism: No Finer a Cause on the Planet”

January 14, 2002        News Morgue Search  www.feat.org/search/news.asp

RESEARCH

Abstracts

·        The Children’s Communication Checklist In A Clinical Setting

·        Relaxation Training On The Disruptive Behavior Of An Autistic Boy

·        Autistic Kids Receiving Parent-Managed Intensive Interventions

·        Enhanced Discrimination In Autism

·        Can Checklist Sort Autism from Developmental Delays in Toddlers?

·        Parents’ Perspectives on the MMR Immunisation

·        Mind Blindness And The Brain In Autism.

·        The Genetics Of Autism.

·        Pervasive Developmental Disorder And Parental Adaptation

 

The Children’s Communication Checklist In A Clinical Setting

Parent and teacher report of pragmatic aspects of communication: use of the children’s communication checklist in a clinical setting.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_ui ds=11769267&dopt=Abstract <- - address ends here.  Bishop DV, Baird G.

Department of Experimental Psychology, University of Oxford, UK.

dorothy.bishop@psy.ox.ac.uk

The Children’s Communication Checklist (CCC) was developed to provide an objective assessment of pragmatic aspects of children’s communication difficulties. We aimed to (1) see whether the checklist provided valid and reliable information when completed by parents, and (2) consider its usefulness in a clinical context.

Checklists were completed by parents and a professional who knew the child well for all 5 to 17-year-old referrals to a tertiary developmental paediatrics centre over a 31-month period. Children who were not yet speaking in sentences were excluded. From a sample of 151 children (81% male; mean age 8.7 years) with pervasive or specific developmental disorders, valid checklists were completed by 119 parents and 93 professionals.

Reliability, as measured by internal consistency, was 0.7 or higher for most scales. Correlations between ratings for parents and professionals were in the range of 0.30 to 0.58 for individual pragmatic scales, with a correlation of 0.46 (n=82) for the pragmatic composite.

For both parents and professionals, the pragmatic composite was lowest for children with a diagnosis of autism; intermediate for those with a diagnosis of Asperger syndrome, pervasive developmental disorder not otherwise specified or attention-deficit-hyperactivity disorder (ADHD); and highest for those with a diagnosis of specific learning disability. The strongest relation between the pragmatic composite and diagnosis was seen when ratings from parents and professionals were combined. Differences between diagnostic groups were not explicable in terms of age or verbal IQ.

PMID: 11769267 [PubMed - in process]

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Relaxation Training On The Disruptive Behavior Of An Autistic Boy The effects of progressive relaxation training on the disruptive behavior of a boy with autism.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_ui ds=11768670&dopt=Abstract <- - address ends here.  Mullins JL, Christian L.  University of Kansas, USA.

This study examined the effects of progressive relaxation training on the disruptive behaviors of a boy with autism. Moreover, his overt relaxed behaviors before and after relaxation training were measured using the Behavioral Relaxation Scale (Poppen, 1988, Poppen, 1998).

After the participant received training in progressive relaxation procedures a multielement design with three conditions was utilized to determine the effects of the procedures on the duration of the boy’s disruptive behaviors during leisure activity sessions.

The conditions were: (a) relaxation prior to a leisure activity session; (b) cued relaxation; and (c) no relaxation prior to the session, which represented a baseline condition. Results indicated that the participant acquired progressive relaxation skills, displayed more relaxed behaviors after performing the procedures, and showed a decrease in the duration of his disruptive behaviors upon completing progressive relaxation training prior to a leisure activity session. Implications for future research are discussed.

PMID: 11768670 [PubMed - in process]

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Autistic Kids Receiving Parent-Managed Intensive Interventions Progress and outcomes for children with autism receiving parent-managed intensive interventions.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_ui ds=11768669&dopt=Abstract <- - address ends here.  Bibby P, Eikeseth S, Martin NT, Mudford OC, Reeves D.

Autism & Developmental Disorders Education Research, London, England, United

Kingdom. PeterJBibby@compuserve.com

Parent-managed behavioral interventions for young children with autism are under-researched. We analyzed data from 66 children served by 25 different early intervention consultants. After a mean of 31.6 months of intervention IQ scores had not changed (N = 22). Vineland adaptive behavior scores had increased significantly by 8.9 points (N = 21). No children aged > 72 months attained normal functioning, i.e., IQ > 85 and unassisted mainstream school placement (N = 42).

Progress for 60 children across 12 months was found for mental age (5.4 months), adaptive behavior (9.7 months), and language (5.1 months). The interventions did not reproduce results from clinic-based professionally directed programs. The effectiveness of the parent-managed intervention model as it has developed and the adequacy of professional services in that model are discussed.

PMID: 11768669 [PubMed - in process]

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Enhanced Discrimination In Autism

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_ui ds=11765744&dopt=Abstract <- - address ends here.  O’Riordan M, Plaisted K.

Department of Experimental Psychology, University of Cambridge, UK.

mafo100@cus.cam.ac.uk

Children with autism are superior to typically developing children at visual search tasks (O’Riordan, Plaisted, Driver, & Baron-Cohen, in press;

Plaisted, O’Riordan, & Baron-Cohen, 1998b). This study investigates the reasons for this phenomenon. The performance of children with autism and of typically developing children was compared on a series of visual search tasks to investigate two related problems. The first issue was whether the critical determinant of search rate in children is the discriminability of the display items, as it is in normal adults.

The second question investigated was whether the superior performance of individuals with autism on visual search tasks is due to an enhanced ability to discriminate between display items. The results demonstrated that discriminability is the rate-determining factor for children with and without autism, replicating earlier findings with normal adults, and that children with autism have an enhanced ability to discriminate between display items. Thus, it seems that an enhanced ability to discriminate between display items underlies superior visual search in autism.

PMID: 11765744 [PubMed - in process]

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Can Checklist Sort Autism from Developmental Delays in Toddlers?  Can the checklist for autism in toddlers differentiate young children with autism from those with developmental delays?

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_ui ds=11765292&dopt=Abstract <- - address ends here.  Scambler D, Rogers SJ, Wehner EA.

JFK Partners, University of Colorado Health Sciences Center, Denver 80262,

USA. doug.scambler@uchsc.edu

OBJECTIVE: The Checklist for Autism in Toddlers (CHAT) has been demonstrated to be sensitive to the presence of autism in otherwise normally developing 18-month-old children. However, its ability to differentiate autism from other significant developmental delays is unknown. This study examined this question.

METHOD: The CHAT was applied to a group of 44 children aged 2 and 3 years, rigorously diagnosed with autism or with other developmental problems.

RESULTS: By the original CHAT authors’ criteria, the sensitivity and specificity of the CHAT were 65% and 100%, respectively. Slightly altering the criteria resulted in a sensitivity of 85% in the current group of children with developmental disabilities while maintaining specificity of 100%.

CONCLUSIONS: The current study is the first to demonstrate that the CHAT successfully discriminates 2-year-old children with autism from those with other developmental disorders. In addition, the increased sensitivity of the Denver Criteria in children with developmental disabilities may improve its usefulness as a screening tool for community-based early-diagnostic teams and general practitioners.

PMID: 11765292 [PubMed - in process]

 

 

 

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Parents’ Perspectives on the MMR Immunisation

A focus group study.

 

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_ui ds=11761204&dopt=Abstract <- - address ends here.  Evans M, Stoddart H, Condon L, Freeman E, Grizzell M, Mullen R.

Division of Primary Health Care, University of Bristol.

m.a.evans@bristol.ac.uk

BACKGROUND: The uptake of the combined measles, mumps and rubella immunisation (MMR) in Britain has fallen since 1998, when a link was hypothesised with the development of bowel disorders and childhood autism.  Despite reassurances about the safety of MMR, uptake levels remain lower than optimal. We need to understand what influences parents’ decisions on whether to accept MMR or not so that health professionals can provide a service responsive to their needs. AIM: To investigate what influences parents’ decisions on whether to accept or refuse the primary MMR immunisation and the impact of the recent controversy over its safety.

DESIGN: Qualitative study using focus group discussions.

SETTING: Forty-eight parents, whose youngest child was between 14

months and three years old, attended groups at community halls in six localities in Avon and Gloucestershire. METHODS: Purposive sampling strategy was used to include parents from a variety of socioeconomic backgrounds.  Three groups comprised parents who had accepted MMR and three groups comprised parents who had refused MMR. Data analysis used modified grounded theory techniques incorporating the constant comparative method.

RESULTS: All parents felt that the decision about MMR was difficult and stressful, and experienced unwelcome pressure from health professionals to comply. Parents were not convinced by Department of Health reassurances that MMR was the safest and best option for their children and many had accepted MMR unwillingly. Four key factors influenced parents’ decisions:

(a)  beliefs about the risks and benefits of MMR compared with contracting the diseases,

(b)  information from the media and other sources about the safety of

MMR,

(c)  confidence and trust in the advice of health professionals and attitudes towards compliance with this advice, and

(d)  views on the importance of individual choice within Government policy on immunisation.

CONCLUSIONS: Parents wanted up-to-date information about the risks and benefits of MMR to be available in advance of their immunisation appointment. Many parents did not have confidence in the recommendations of health professionals because they were aware that GPs needed to reach immunisation targets. Most parents would, however, welcome more open discussion about immunisation with health professionals.

PMID: 11761204 [PubMed - in process]

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Mind Blindness And The Brain In Autism.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_ui ds=11754830&dopt=Abstract <- - address ends here.  Frith U.

UCL Institute of Cognitive Neuroscience, 17 Queen Square, WC1N 3AR, London,

United Kingdom

Experimental evidence shows that the inability to attribute mental states, such as desires and beliefs, to self and others (mentalizing) explains the social and communication impairments of individuals with autism.

Brain imaging studies in normal volunteers highlight a circumscribed network that is active during mentalizing and links medial prefrontal regions with posterior superior temporal sulcus and temporal poles. The brain abnormality that results in mentalizing failure in autism may involve weak connections between components of this system.

PMID: 11754830 [PubMed - in process]

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The Genetics Of Autism.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_ui ds=11753107&dopt=Abstract <- - address ends here.  Spence MA.

University of California, Irvine, Medical Center, Department of Pediatrics, Orange, California, USA.

Autism is a significant childhood disorder. Studies are underway to define more clearly the disorder and its various manifestations and to correlate this information with an etiology.

Genes are known to play an important role in autism, and a vigorous search is underway to define those genes.

The Human Genome Project provides the basis that allows us to move beyond single gene disorders and to contemplate progress for complex disorders, such as autism.

Genome screens of affected siblings and detailed molecular analyses of chromosome abnormalities identified in autistic subjects has led in the past year to the identification of several candidate genes. However, the problem of determining which are the real genes remains.

This is complicated because the presentation of the disorder is so variable, and milder manifestations in relatives are not yet understood. But the fact that we can now name possible genes for this disorder reflects how quickly our understanding is progressing.

PMID: 11753107 [PubMed - in process]

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Pervasive Developmental Disorder And Parental Adaptation Previewing and reviewing atypical development with parents in child psychiatric consultation.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_ui ds=11751642&dopt=Abstract <- - address ends here.  Schuntermann P.

Department of Psychiatry, Harvard Medical School, Children’s Hospital, and Beth Israel Deaconess Medical Center, Boston, Mass., and the Developmental Consultation Service of Harvard Vanguard Medical Associates, Somerville, Mass.

Parenting young children with pervasive developmental disorder engenders unique sustained stresses, which have been termed “burden of care.” One specific source of stress for parents is the children’s uneven developmental progress, in which delays and accelerations of adaptive functioning may exist side by side.

This paper proposes a clinical method that may be incorporated into periodic child psychiatric consultations with parents of young children who have high-functioning autism or Asperger’s disorder. Using a semistructured technique, the clinician reviews with the parents the details of the child’s recent developmental course and attempts to identify emergent skills that may serve to preview upcoming developmental issues and gains. This method is aimed at enhancing parental abilities to track and anticipate developmental progress and the resultant shifts in the parent-child relationship, in order to reduce one source of sustained parental stress. Case illustrations of children ages 2-8 years old are discussed in light of recent literature on adaptive issues in families of individuals with a chronic medical or psychiatric condition and, specifically, families of children with pervasive developmental disorder.

PMID: 11751642 [PubMed - in process]

 

 

 

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