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“Healing Autism: No Finer a Cause on the Planet”

January 9, 2002        News Morgue Search  www.feat.org/search/news.asp

COMMENTARY

·        A Shot In The Arm

 

RESEARCH

Abstracts - Behavioral

 

·        Outcome Of Early Intensive ABA For ASD Kids In A

Community Set

·        Predictors of Treatment Outcome In ASD Kids:

Retrospective Study

·        Increasing Joint Attention, Play & Language

Via Peer Play

·        The Scottish Centre for Autism Preschool Treatment

Programme

·        Predicting Spoken Language Level In ASD Children

·        Classical Eyeblink Conditioning: Clinical Models

And Applications

·        Use of Multimedia & Therapist-Instructed Training For

ASD Kids

·        Use of Multimedia & Therapist-Instructed Training For ASD Kids

 

COMMENTARY

A Shot In The Arm

Sarah Boseley

 

There are likely to be outbreaks of measles because the MMR scare means fewer children are being vaccinated. But does that really matter?

[By Sarah Boseley in The Guardian .]

http://www.guardian.co.uk/analysis/story/0,3604,629666,00.html

Outbreaks of measles are once again possible because parental anxiety about MMR means more and more children are not being vaccinated. Does it really matter? Measles was once a fact of life, as much a part of childhood as rocking horses and climbing trees.

Many people will have had it when they were less than five years old.  Measles parties are part of our folk lore. Some parents used to take their small children to houses where there was measles, or for that matter chicken pox, with the idea of catching hopefully a mild dose and becoming immune for life.

What few remember is that measles is a killer - because the death rate in the UK was always low, so the chances of knowing a family that had lost a child to measles were small. In 1980, 18 children under the age of four died of measles and five over that age. It was a bad year. In most of that decade, the total number of deaths per year did not exceed 10. Yet this was after the introduction of the single measles vaccination which was introduced in 1968. Before there was any immunisation available, there were between 160,000 and 800,000 cases of measles annually in the UK. In an epidemic year - because measles, left to itself, tends to be cyclical - it would cause more than 100 deaths.

The virus, which is incredibly infectious, kept children in bed for about five days with fever, rash, a cough, red and painful eyes, swollen glands and a loss of appetite. One in 100 had to be admitted to hospital, one in 20 got an ear infection, one in 200 went into convulsions and one in a thousand ended up with meningitis or encephalitis. The most unfortunate - one in 8,000 - got SSPE (subacute sclerosing panencephalitis) which would set in about eight years after their measles bout, causing brain damage and eventually early death. There are still deaths from measles in the UK - but they are all due to SSPE in children who contracted measles as a child before the MMR came in.

In spite of the unpleasant and sometimes tragic consequences of measles, the take-up of the single vaccine after 1968 was low - perhaps because the disease was so common and such a predictable childhood event which in the majority passed with no ill-effects. But the low take-up troubled public health officials who were aware as most of the general public would not have been at that time that children in the UK were unnecessarily dying. It was one of the reasons why the combined measles, mumps and rubella (MMR) vaccination was introduced two decades later, in 1988.

Mumps is not a killer although it can have damaging consequences such as deafness and can lead to meningitis. However, rubella, also known as German measles, is a disaster for pregnant women, whose babies can be born deaf, blind, brain damaged or with heart or other serious problems. Adolesce nt girls used to be vaccinated in schools. The decision was taken to put the vaccines together and work for the immunity of the entire population from all three diseases. The population was at first persuaded. Take-up of the first dose of MMR at around 15 months (to be followed by a pre-school booster) hit a high of 92% in the mid-1990s. But the controversial work of Andrew Wakefield and colleagues of the Royal Free Hospital Inflammatory Bowel Disease Study Group, published in the Lancet in 1998, has undermined public confidence. Coverage has now dropped to 84.2% nationally, according to the latest figures from the Public Health Laboratory Service from April-June last year. There are patches of the country which are far worse.  North Cheshire made headlines a few days ago by publishing a figure of 77%, but in London, take-up has hit an all-time low of 72.3%.

The World Health Organisation says only 95% coverage will ensure there are no outbreaks. The UK is not facing a major epidemic of the pre-1968 scale because most parts have above 80% coverage, but it is more than possible that there will be localised outbreaks. The belief that measles is a minor ailment which children are better off catching and getting over never quite went away and tends now to be aired again by many who are frightened that the MMR may damage their child. Dr Wakefield, who led the research into a possible link between the vaccination, bowel disease and autism (in fact the Lancet paper conceded that no link had been found) has recently left the Royal Free.

Scientific institutions on both sides of the Atlantic have produced vast numbers of safety studies of the vaccines and analyses of Wakefield’s work and invariably concluded that the measles vaccine - whether live or in attenuated form in an injection - is not responsible for the sharp rise in autism which has undoubtedly and worryingly occurred in the UK and the US.

Nobody has managed to prove to the satisfaction of the scientific community that the measles virus has been found in the gut of children with either bowel disease or autism. But in spite of the mountain of scientific data and opinion backing the safety of the MMR - the latest being a paper in the prestigious American journal, Paediatrics, which says a child’s immune system could cope with 10,000 vaccines at one time if it had to - the figures show a continuing loss of confidence on the part of parents.

Public health officials fear we could see sudden deaths once more from measles. Their assessment is categorically that the risk of the deaths of even a few children outweighs any risk from the MMR. It may not be until deaths start to occur once more - and these days they would soon be common knowledge - that the pendulum will swing back and vaccination rates rise once more.

·        Sarah Boseley is the Guardian’s health editor.

* * *

 

Outcome Of Early Intensive ABA For ASD Kids In A Community Set

Outcome survey of early intensive behavioral intervention for young children

with autism in a community setting

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_ui ds=11777258&dopt=Abstract <- - address ends here.

Boyd RD, Corley MJ.

Golden Gate Regional Center, San Francisco, CA, USA.

This article presents findings from an outcome survey of the effects of early intensive behavioral intervention (EIBI) for young children with autism in a community setting. Results from both individual case reviews and parent questionnaires are presented, with the data failing to support any instances of’recovery’ while still yielding a high degree of parental satisfaction with the treatment.

Moreover, a follow-up inquiry into the type of services each child was receiving in his or her post-EIBI setting documents continued dependence on extensive educational and related developmental services, suggesting that the promise of future treatment sparing did not materialize. Limitations of the survey in evaluating community-based EIBI services are discussed along with the need for further research designed to document the effectiveness of services provided to young children with ASD in the community.

PMID: 11777258 [PubMed - in process]

* * *

 

Predictors of Treatment Outcome In ASD Kids: Retrospective Study

Predictors of treatment outcome in young children with autism: a

retrospective study

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_ui ds=11777257&dopt=Abstract <- - address ends here.

Gabriels RL, Hill DE, Pierce RA, Rogers SJ, Wehner B.

University of Colorado Health Sciences, Denver 80262, USA.

robin.gabriels@uchsc.edu

This study examined predictors of developmental outcomes in 17 children diagnosed with autism or PDD-NOS, who received generic treatment over a mean period of 37 months. Pre-treatment evaluations occurred at a mean age of 31 months with follow-up evaluations at a mean age of 69 months.  Significantly different developmental trajectories were observed among the participants at follow-up, separating the participants into two distinct groups (high and low outcome).

However, groups did not differ significantly in treatment intensity or other outcome prediction measures. Pre-treatment developmental intelligence levels between the two groups approached significance. The results raise questions regarding the effect of treatment intensity and type, family stress factors, and intelligence ability in very early childhood on, outcome.

PMID: 11777257 [PubMed - in process]

 

 

 

 

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* * *

 

Increasing Joint Attention, Play & Language Via Peer Play

Increasing joint attention, play and language through peer supported play

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_ui ds=11777255&dopt=Abstract <- - address ends here.

Zercher C, Hunt P, Schuler A, Webster J.

San Francisco State University, CA, USA. craig.zercher@sri.com

The purpose of the present study was to examine the effects of participation in an integrated play group on the joint attention, symbolic play and language behavior of two young boys with autism. Two 6-year-old twin brothers participated in this study, along with three typically developing girls, ages 5, 9 and 11. A multiple baseline design was used with three phases: no intervention, intervention with adult coaching, and intervention without adult coaching.

After being trained, the three typically developing children implemented the integrated play group techniques in 30 minute weekly play group sessions for over 16 weeks. Results indicate that participation in the integrated play group produced dramatic increases in shared attention to objects, symbolic play acts, and verbal utterances on the part of the participants with autism. These increases were maintained when adult support was withdrawn. Implications of these findings for inclusion of children with autism are discussed.

PMID: 11777255 [PubMed - in process]

* * *

 

The Scottish Centre for Autism Preschool Treatment Programme I:

A developmental approach to early intervention.  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_ui ds=11777254&dopt=Abstract <- - address ends here.

<- - address ends here.

Salt J, Sellars V, Shemilt J, Boyd S, Coulson T, McCool S.

Scottish Centre for Autism, Department of Child and Family Psychiatry,

Yorkhill NHS Trust, Glasgow, UK. jeff_salt@hotmail.com

Early intervention is an area of intense current interest for parents and professionals. This article describes a mainstream National Health Service (NHS) approach to early intervention, developed at the Scottish Centre for Autism. The aims of treatment are to improve the child’s early social communication and social interaction skills, leading to the potential development of play and flexibility of behaviour. This is achieved by 1:1 intensive treatment by trained therapists, and a schedule of parent training. The treatment protocol incorporates a child led approach; the use of imitation as a therapeutic strategy; using language contingent on activities; and the introduction of flexibility into play and social exchanges.

PMID: 11777254 [PubMed - in process]

* * *

 

Predicting Spoken Language Level In ASD Children

Predicting spoken language level in children with autism spectrum disorders http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_ui ds=11777253&dopt=Abstract <- - address ends here.

Stone WL, Yoder PJ.

Vanderbilt University, Nashville, TN, USA. Wendy.Stone@mcmail.vanderbilt.edu

Thirty-five children who received an autism spectrum diagnosis at the age of 2 years (24 with autism, 11 with PDD-NOS) were re-evaluated 2 years later to examine factors related to the development of spoken language.  Child variables (play level, motor imitation ability and joint attention) and environmental variables (socioeconomic status and hours of speech/language therapy between ages 2 and 3) were used to predict an aggregate measure of language outcome at age 4.

After controlling for age 2 language skills, the only significant predictors were motor imitation and number of hours of speech/language therapy. Implications of these results for understanding the early developmental course of autism spectrum disorders and the effects of intervention are discussed.

PMID: 11777253 [PubMed - in process]

* * *

 

Classical Eyeblink Conditioning: Clinical Models And Applications http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_ui ds=11777017&dopt=Abstract <- - address ends here.

       .

Steinmetz JE, Tracy JA, Green JT.

Department of Psychology, Indiana University, Bloomington 47405, USA.

steinmet@indiana.edu

In this paper, we argue that the main reason that classical eyeblink conditioning has proven so useful when applied to clinical situations, is that a great deal of information is known about the behavioral and neural correlates of this form of associative learning. Presented here is a summary of three lines of research that have used classical eyeblink conditioning to study three different clinical conditions; autism, fetal alcohol syndrome, and obsessive-compulsive disorder.

While seemingly very different clinical conditions, classical eyeblink conditioning has proven very useful for advancing our understanding of these clinical pathologies and the neural conditions that may underlie them.

PMID: 11777017 [PubMed - in process]

* * *

 

Use of Multimedia & Therapist-Instructed Training For ASD Kids Effectiveness of a multimedia programme and therapist-instructed training for children with autism.  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_ui ds=11775031&dopt=Abstract <- - address ends here.

Wong SK, Tam SF.

Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hung Hom, Kowloon.

The present study aimed to evaluate the effectiveness of an interactive multimedia training programme and a conventional therapist-instructed training in improving the learning behaviours of children with autism. A multiple-subject, single case-study time-series research design was adopted in the study. Six children with autism, aged 2 years 4 months to 2 years 10 months, were recruited by convenience sampling.  They attended a 12-session training programme on basic concepts (e.g.  colours, shapes) that was presented as an interactive multimedia training programme and also as a conventional, therapist-led training programme.

The attending behaviours and appropriate responses of the subjects were videotaped for further analysis. Participants who attended the conventional therapist-instructed training programme generally showed improvement in attending behaviours and response rates; participants attending the multimedia programme also showed improvement in their attending behaviours and response rates.

The results support the hypothesis that both training programmes are effective in improving the attending behaviours and appropriate responses of children with autism. The authors suggest that, because children with autism respond differently to different training approaches, customized training programmes should be considered for individual children. The implications of the methodology and the potential impact of the present study on the training of children with autism are discussed.

PMID: 11775031 [PubMed - in process]

 

 

 

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