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January 8, 2002        News Morgue Search  www.feat.org/search/news.asp

 

PUBLIC HEALTH

Vaccinations Update

·        U.S. Study Says Multiple Infant Vaccines Safe

·        Docs: Babies Need Hepatitis B Vaccine

·        Opposition to Vaccine Ups Children’s Tetanus Risk

·        1,000 Families Seek Compensation For Alleged Vaccine Harm

·        Reader’s Posts

 

 

U.S. Study Says Multiple Infant Vaccines Safe

[By Michael Conlon in Reuters.]

http://dailynews.yahoo.com/h/nm/20020107/sc/health_vaccines_dc_1.html

Today’s children, who receive as many as 11 vaccinations routinely, are not in danger of having their immune system overwhelmed, according to a study published on Monday.

“Current studies do not support the hypothesis that multiple vaccines overwhelm, weaken, or ‘use up’ the immune system,” said the report from Children’s Hospital of Philadelphia and several other institutions.

“On the contrary, young infants have an enormous capacity to respond to multiple vaccines, as well as to the many other challenges present in the environment,” it added.

“By providing protection against a number of bacterial and viral pathogens, vaccines prevent the ‘weakening’ of the immune system and consequent secondary bacterial infections occasionally caused by natural infection,” it added.

The report was published in this month’s issue of “Pediatrics,” the journal of the American Academy of Pediatrics. The authors said they investigated the subject because recent surveys in the United States indicated that about a quarter of all parents were concerned about the possible negative impacts of multiple vaccinations.

A century ago, the study said, children received only one vaccination, for smallpox. Forty years ago four others came into common use—for polio, diphtheria, whooping cough and tetanus. Today children in developed countries receive 11 vaccines routinely and will have had as many as 20 completion shots by age two, the report added.

Capacity To Cope With 10,000 Vaccines

By a conservative estimate infants have the theoretical capacity to respond to as many as 10,000 vaccines, it said.

“Parents who are worried about the increasing number of recommended vaccines may take comfort in knowing that children are exposed to fewer antigens (proteins and polysaccharides) in vaccines today than in the past,” the report said.

“Although we now give children more vaccines, the actual number of antigens they receive has declined. Whereas previously one vaccine, smallpox, contained about 200 proteins, now the 11 routinely recommended vaccines contain fewer than 130 proteins in total,” it added.

“Two factors account for this decline: First, the worldwide eradication of smallpox obviated the need for that vaccine, and second, advances in protein chemistry have resulted in vaccines containing fewer antigens ...”

In a related development, the academy in the same issue published its annual recommendation for immunizations, saying there were no major changes to suggested timetables except one involving pneumococcal vaccine. Because there is a shortage of that vaccine, it said, healthy children should receive only the first three doses and doctors should defer the fourth or booster shot until the shortage eases.

The vaccine wards off pneumonia, meningitis and bloodstream infections. The U.S. manufacturer of the vaccine has reported it has been unable to keep up with demand.

* * *

 

Docs: Babies Need Hepatitis B Vaccine

[By Lindsey Tanner via The Associated Press. Hepatitis B is contracted

through intravenous drug use and sexual contact. Newborns can get it from

so-acting mothers. Thanks to S. Mendez.]

http://www.washingtonpost.com/wp-dyn/articles/A6615-2002Jan7.html

All U.S. newborns should be vaccinated against hepatitis B before leaving the hospital to protect against possible disease from infected mothers, doctors recommend.

Previously, giving the shots in the hospital was recommended only for newborns whose mothers were known to be infected or whose disease status was unknown.

The new recommendation is listed in the childhood immunization schedule for 2002, prepared by the American Academy of Pediatrics, the Centers for Disease Control and Prevention’s Advisory Committee on Immunization Practices, and the American Academy of Family Physicians.

It is a minor change from the group’s list last year. For one of the first times in recent years, no new shots are recommended; both lists recommend a series of seven vaccine shots starting in infancy for all U.S.  children.

The list is published in January’s Pediatrics.

The recommendation for hepatitis B shots was made out of concern that

some infants of mothers mistakenly thought to be disease-free might be falling through the cracks, said Dr. Julia McMillan, a member of the AAP committee that helped create this year’s list.

Doctors also worried that some infants were not being vaccinated early because of concerns that some shots had a mercury-containing preservative called Thimerosal, which has since been removed from most vaccines, said Dr.  Louis Cooper, AAP president.

While there’s been no known increase in infants infected with hepatitis B, vaccinating them before they leave the hospital “just makes good sense,” Cooper said.

Newborns can contract the virus from infected mothers’ blood during childbirth, but vaccinating them soon afterward can prevent the disease from taking hold, said McMillan, a pediatrics professor at Johns Hopkins University.

The seven recommended vaccines are: hepatitis B; diphtheria, tetanus and pertussis combined; haemophilus influenza type b; inactivated polio; measles, mumps, rubella combined; chickenpox; and pneumococcal vaccine.  Hepatitis A and flu vaccines are recommended for certain at-risk children.

McMillan noted that because of a current shortage of pneumococcal vaccine – which protects against childhood pneumonia, meningitis and ear infections – doctors are urged to reserve the full four-shot series for at-risk children with weakened immune systems until supplies rebound.

Vaccine maker Wyeth-Ayerst Laboratories has said it expects the shortage, blamed on unforeseen demand, to ease by the end of March.

On the Net: Academy of Pediatrics:

http://www.pediatrics.org/cgi/content/full/109/1/162/F1

CDC: http://www.cdc.gov

 

 

 

 

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* * *

 

Opposition to Vaccine Ups Children’s Tetanus Risk

 

http://www.reutershealth.com/archive/2002/01/07/eline/links/20020107elin003.  html <- - address ends here.

Reuters Health - Children whose parents decide not to vaccinate them against tetanus are at risk of contracting the potentially serious disease, according to researchers.

Tetanus is an infection that occurs when a toxin found in soil and animal and human intestines enters the body through a wound. The disease, which is not contagious, leads to muscle spasms and may be fatal.

The study of 15 cases of tetanus in children younger than 15 years found that 80% had not been vaccinated due to their parents’ religious or philosophic objections. Vaccinated children had milder illness compare with unvaccinated children. Although none of the children died, all were hospitalized and about two-thirds were put on a respirator.

Two cases of tetanus occurred in infants younger than 10 days old and 13 were diagnosed in children aged 3 to 14 years, the report indicates.

Typically, US children are inoculated against tetanus at 2, 4 and 6 months, and 15 to 18 months of age. The vaccine, known as DTP, is given along with an inoculation against diphtheria, a potentially fatal infection that damages the heart and central nervous system, and pertussis (whooping cough), a highly contagious respiratory infection.

In recent years, an increasing number of parents have decided not to vaccinate their children against a handful of diseases, some potentially fatal, due to concerns about the safety of vaccines, the belief that these diseases are rare, and the belief that parents can protect their children.

But according to the report in the January online edition of the journal Pediatrics, these decisions can put children at risk of contracting tetanus.

“Parents who choose not to vaccinate their children should be advised of the seriousness of the disease and be informed that tetanus is not preventable by means other than vaccination,” conclude Elizabeth Fair from Stanford University School of Medicine in Stanford, California, and colleagues.

According to their report, all US states require children entering school to be vaccinated against tetanus. However, the majority of states also recognize religious and medical exemptions, while 15 states recognize philosophic objections.

“Tetanus in individuals who are not protected can result from mild injury and can cause life-threatening disease even with the availability of intensive medical care,” Fair’s team concludes.

Source: Pediatrics online 2002;109:e2.

Copyright © 2002 Reuters Limited.

* * *

 

1,000 Families Seek Compensation For Alleged Vaccine Harm

[By Richard Woodman via Reuters Health, UK.] http://www.reutershealth.com/archive/2002/01/07/eline/links/20020107elin021.  html <-- address ends here.

More than 1,000 British families have joined a legal battle for millions of pounds compensation for harm they claim was caused to their children by measles, mumps and rubella (MMR) vaccines, their solicitors said on Monday.

The case—which is scheduled to come to trial in February 2003--follows controversial research findings suggesting that use of the vaccines could be linked to inflammatory bowel disease and autism.

Two firms of solicitors, Alexander Harris and Freethcartwright, have been appointed as the joint leading firms in the generic litigation against Aventis Pasteur MSD, GlaxoSmithKline and Merck.

A spokeswoman at Alexander Harris said that the firm represented about 1,000 families while the total number involved was probably around 1,500.  She said likely levels of compensation varied but could be worth several million pounds for children with serious brain damage.

The firm’s Web site says that the case is being brought under the Consumer Protection Act—part of the European Union’s Product Liability Directive that imposes liability on manufacturers of products for any injury caused by an unsafe product. The families had been granted public funds to pay for the legal action.

The firm said that the UK Department of Health stopped using SmithKline Beecham’s Pluserix and Aventis Pasteur MSD’s Immaravax in 1992, two years after a similar vaccine containing the Urabe strain of mumps vaccine virus was withdrawn in Canada after reports of meningitis.

“After we had been contacted by several hundred families a clear pattern began to emerge,” the solicitors said. “Children who were developing well, both physically and intellectually, before the vaccine, regressed after vaccination, often accompanied by other symptoms and a gradual decline into autism.”

They added: “It is important to stress that we appear to be dealing with cases where the children, who were fit and well before being vaccinated and were developing normally in every way, are now chronically ill and as a result many are seriously mentally or physically disabled.”

A spokesman for GlaxoSmithKline said that all the manufacturers were still trying to clarify exactly what was being alleged by the families. He added that numerous studies had failed to show a link between MMR vaccination and autism, and that the legal action would be defended.

The Department of Health and the Medical Research Council have also

dismissed reports by researchers at London’s Royal Free Hospital suggesting

that the triple vaccine may trigger autism. Copyright © 2002 Reuters Limited

* * *

 

Reader’s Posts

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I am a Year 12 student at Gilgandra High School in New South Wales in

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Looking for a good child psychiatrist in the South Metro Minneapolis area

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ALL INFORMATION, DATA, AND MATERIAL CONTAINED, PRESENTED, OR PROVIDED HERE IS FOR GENERAL INFORMATION PURPOSES ONLY AND IS NOT TO BE CONSTRUED AS REFLECTING THE KNOWLEDGE OR OPINIONS OF THE PUBLISHER, AND IS NOT TO BE CONSTRUED OR INTENDED AS PROVIDING MEDICAL OR LEGAL ADVICE.  THE DECISION WHETHER OR NOT TO VACCINATE IS AN IMPORTANT AND COMPLEX ISSUE AND SHOULD BE MADE BY YOU, AND YOU ALONE, IN CONSULTATION WITH YOUR HEALTH CARE PROVIDER.