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AUTISM FIRST STEPS
AUTISM DAILY NEWSLETTER     
Wednesday January 9, 2002  


INDEX:
*  Savoring Victory, Bush Signs Education Bill
*  
Education Bill at a Glance
*  Education Bill Signing Sets Off Seismic Shift to States
*  
Health Care Spending Climbed in 2000, Report Says
*  
Proteins Needed To Ensure Accurate Chromosome Copies
*  
Immune system protein linked to ADHD  
*  
Soon-to-be-ex-governor gives his pen a workout
*  
When your 3-year-old isn’t talking

*
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Savoring Victory, Bush Signs Education Bill


President Hails 'New Path' for Nation's Schools


By RON FOURNIER
.c The Associated Press

HAMILTON, Ohio (Jan. 8) - President Bush sat at school desk Tuesday and signed the most far-reaching federal education bill in nearly four decades, a $26 billion plan to broaden academic testing, triple spending for literacy programs and help children escape America's worst public schools.

''We've spent billions of dollars with lousy results,'' the president said. ''Now it's time to spend billions of dollars and get good results.''

With his signature, Bush fulfilled a campaign promise to increase federal education spending and offer the money as incentive to make states and educators accountable for failures in teaching the nation's 48 million public school students.

''We do not want children trapped in schools that will not change and will not teach,'' Bush told several hundred foot-stomping students, teachers and parents in a packed high school gym.

Though some of his initial ideas did not survive in Congress, Bush claimed success on his top domestic priority. He meets Wednesday with educators and will urge them to implement the changes. He may propose an education tax credit later in the year, aides said.

Bush signed the foot-thick bill behind a worn, wooden school desk and a sign that read, ''No child left behind.'' The shrieks and squeals of students were an ear-rattling reminder of Bush's high approval ratings since the Sept. 11 terrorist attacks.

Drawing from his popularity as commander in chief, Bush pledged to win a war against illiteracy as well as the war in Afghanistan.

''As of this hour, American schools will be on a new path of reform,'' the president said.

The most immediate changes will appear next school year when children in some 3,000 poorly run schools will be eligible for taxpayer-financed tutoring or other educational services. The money can go to private companies and religious institutions.

Children in an additional 6,700 failing schools will be eligible for transfers to more successful public schools, and federal money could pay for their transportation.

A new regime of student tests in math, reading and science will begin to take effect in the fall of 2005, identifying more failing schools that could lose federal money as students take advantage of the new options.

After a year of debate, a strong majority of Democrats and Republicans approved the bill - a rare point of bipartisanship that Bush hopes will impress voters weary of political bickering. He celebrated its passage during a 12-hour, 1,600-mile swing through the states of lawmakers who sponsored the bill.

He signed it in Ohio, in the home district of GOP Rep. John Boehner.

Later, in New Hampshire, home of GOP Sen. Judd Gregg, he said, ''The hope of the future for this country is not only to make sure that we're secure and we're safe, but the true hope for the country is to make sure everybody gets a good education.''

He also was touring the nation's oldest public school, the 365-year-old Boston Latin in Massachusetts, home state of Democratic Sen. Edward Kennedy. The fourth sponsor, Rep. George Miller, D-Calif., also made the trip.

Though Kennedy's liberal policies rankle conservatives, Bush called him a fabulous senator.

Partisan politics had its moments. Bush met privately with GOP donors in New Hampshire, the site of the leadoff presidential primary in 2004. His political team is readying him for a re-election bid.

The education bill authorizes the federal government to spend $26.5 billion, though the actual amount spent will be slightly less. The current budget is $18.5 billion.

The increase form current spending, combined with the strings attached to the money, makes the legislation the most significant federal school measure since the 1960s, many analysts say.

By any measure, it greatly expands the federal government's role in an education system that traditionally protects the autonomy of states, local school boards, teachers and parents. Changes won't come easy, even with the bill's passage.

The Bush administration promises to strictly uphold the standards, though aides privately acknowledge there will always be a reluctance to strip money or power from local schools.

The bill requires annual state tests in reading and mathematics for every child in grades three through eight, beginning in the fall of 2005. Fifteen states already comply.

Science tests will be added in three grades that same year.

Under current law, states are required to test students in reading and math - once in elementary school, once in middle school and once in high school.

Schools whose scores fail to improve two years in a row could receive more federal money to help improve skills. If scores still don't improve, low-income students can receive tutoring or transportation to other public schools.

Schools that fail to improve for six years could have staff changes forced upon them.

The bill also triples money for literacy programs to $1 billion per year. It sets a 12-year goal to improve academic proficiency of students who are poor, who speak limited English or have various disabilities.

States must develop annual report cards comparing each school's tests scores.

AP-NY-01-08-02 1636EST

AOL News: Bush Savors Victory, Signs Education Bill

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Education Bill at a Glance


.c The Associated Press

Details of the education bill to be signed Tuesday by President Bush:

-Authorizes $26.5 billion for the 2002 budget year, which began Oct. 1, for K-12 education. That is about $8 billion more than the year before. It is $4 billion above what President Bush requested but nearly $6 billion below the level Senate Democrats wanted.

-Requires annual state tests in reading and math for every child in grades three through eight beginning in the 2005-2006 school year. Schools whose scores fail to improve two years in a row could receive more federal aid. If scores still fail to improve, low-income students can receive money for tutoring or transportation to another public school. A school in which scores fail to improve over six years could have staff changes. In schools already considered poor performers, parents could receive tutoring or transportation funds for their children as early as the fall.

-Requires schools to raise all students to reading and math proficiency in the next 12 years. Schools also must close gaps in scores between wealthy and poor students and white and minority students.

-Allows churches or other religious groups to provide tutoring and after-school programs.

-Requires schools to ensure that within four years all teachers are qualified to teach in their subject area. Schools could require teachers to pass subject tests or major in their field in college. If a teacher isn't qualified to teach in his or her subject area, a school would be required to send a letter notifying parents.

-Allows school districts to spend federal teacher-quality funds on other purposes - training, hiring or raises for teachers, for example.

-Provides aid to build new charter schools and help existing ones.

-Requires schools to develop periodic ''report cards'' showing a school's standardized test scores compared with both local and state schools. The reports would also show two-year trends in scores and compare the percentage of qualified teachers in a school to other schools and school districts throughout the state.

-Provides nearly $1 billion per year for the next five years to improve reading - three times as much as this year - with a goal of making sure every student can read by third grade.

-Allows states to use a small portion of their federal funds as they wish. A pilot program further frees seven states and 150 school districts from most restrictions on spending.

-Requires schools to test students with limited English skills to ensure they are proficient in English after three consecutive years of attending school in the United States.

-Takes away federal funds from any district that discriminates against the Boy Scouts or similar groups that bar homosexuals.

-Provides money to help schools form partnerships with colleges and universities to improve science and math instruction.

AP-NY-01-07-02 1535EST


Copyright 2002 The Associated Press. The information contained in the AP news report may not be published, broadcast, rewritten or otherwise distributed without the prior written authority of The Associated Press.  All active hyperlinks have been inserted by AOL.

AOL News: Education Bill at a Glance

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Education Bill Signing Sets Off Seismic Shift to States


US Newswire
January 08, 2002

WASHINGTON, Jan 8, 2002 (U.S. Newswire via COMTEX) -- With the flourish of his presidential pen, President George W. Bush will set off a seismic shift of responsibility and mandates to American state governments and schools, the National Education Association (NEA) said today. As the Elementary and Secondary Education Act was signed into law, NEA President Bob Chase urged state lawmakers and schools to let common sense be their guide in implementing the new law to maximize, rather than reduce, student learning. "The true test of this bill's mettle will be in the states," said Chase. "As states begin implementing the new testing provisions, policymakers must practice common sense and let two principles prevail -- to help or at least do no harm." To avoid the pitfalls many states experienced with poorly developed testing and accountability systems, NEA joined other education groups to produce a guide for state policymakers to implement quality tests. (www.aasa.org/issues_and_insights/assessment/Building_Tests.pdf) "States cannot implement tests on the cheap and expect to improve student achievement," said Chase. Chase said the testing and accountability measures in the final package are dramatically improved and focuses more on fixing problems, rather than merely labeling and abandoning the schools that need the most help. As a result, states are directed to use high quality tests and to provide parents and policymakers information that provides a more complete picture of student learning -- not just one test score. "If done correctly, this is the kind of accountability that will help close the achievement gap and target action to schools that need the most help," said Chase. With 44 states facing budget deficits, federal help in footing the extra cost of education reform is imperative. Chase urged Congress and the President to complete work in making up the special education shortfall when Congress reconvenes on January 23. "Inadequate support provided to states that are suffering severe economic decline is lamentable," said Chase. "This bill imposes multi-year mandates on states and schools without providing multi-year funding." Congress is scheduled to reauthorize the Individuals with Disabilities Education Act (IDEA) this year -- a prime opportunity to rescue states from a fiscal burden that hurts children and public education. Congress' refusal to pay its pledged fair share and the current economic slump has forced states to cut more than $11 billion from their education budgets in the past year. In response to budget cuts, schools across the nation are increasing class sizes, delaying purchases of classroom technology, and scaling back after-school classes. According to the National Governors' Association, states now face a $35 billion shortfall in the wake of a national recession. The National Education Association is the nation's largest professional employee organization, representing 2.6 million elementary and secondary teachers, college faculty, education support professionals, school administrators, retired educators, and students preparing to become teachers.
Copyright (C) 2002, U.S. Newswire


http://www.brainconnection.com/SITEWare/2002/01/08/us/0000-0706-KEYWORD.Missing.php3
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Health Care Spending Climbed in 2000, Report Says


By JANELLE CARTER
.c The Associated Press

WASHINGTON (Jan. 8) - The cost of the nation's health care rose 6.9 percent to $1.3 trillion in 2000 as Americans spent more on prescription drugs and hospital care, the government says.

Health care spending averaged $4,637 per person, up from $4,377 in 1999, the government said in a report marking what its economists called the ''end of an era of reasonable health care cost growth throughout most of the 1990s.''

''Given what we know, we expect health care costs will continue to grow ... in 2001,'' economist and author of the report Katharine Levit predicted.

The report, released Tuesday by the Health and Human Services Department's Centers for Medicare and Medicaid Services, said there was a 17.3 percent increase in prescription drug spending. Hospital spending in 2000 rose to $412 billion, a 5.1 percent increase over 1999. For the first time in five years, nursing home expenditures increased, by 3.3 percent.

The higher spending in all categories was attributed to the increased bargaining power of hospitals and health providers for higher insurance payments and the aging of the post-World War II baby boomers.

When managed care plans became popular, health care providers often had to deal with payment caps. Now, more providers are rejecting the strict management of costs by health plans, the report said.

As the population ages, health care gradually is becoming a bigger component of the nation's economy, rising from 13.1 percent of the gross domestic product in 1999 to 13.2 percent in 2000, the report said.

Spending on prescription drugs increased by even more, 19.2 percent, in 1999. The rise in 2000 represents the sixth consecutive year the percentage increase in spending on prescriptions was in double digits.

Government economists attributed the 2000 increase to the aging population and consumer demand for newer, higher-priced drugs marketed directly to them on television.

About 15 percent of national health spending represented out-of-pocket expenditures, a share relatively unchanged since 1994. Prescription drugs were the largest component of out-of-pocket spending, 20 percent, the report said.

Those paying out-of-pocket prescription drug costs are mostly older people without insurance coverage, the report said. Physician services accounted for 17 percent of out-of-pocket spending, and over-the-counter drugs for 15 percent.

''These new expenditures are another indication that the burden on consumers is growing,'' said Gail Shearer, who handles health cost issues for Consumers Union, publisher of Consumer Reports magazine. ''It's been a pretty steady increase over the past few decades. The big question is when will this ever end.''

Economists said the recession will create even more out-of-pocket expenses for health-care consumers as employers lay off workers and opt for less expensive insurance plans.

''In this environment, employers are going to be inclined to choose less costly options for health plans,'' said Cynthia Smith, a government health economist. ''Those who are uninsured are going to have a difficult time paying for health care services, and those who are insured are looking at higher premiums.''

The report appears in the January-February issue of the journal Health Affairs.

AP-NY-01-08-02 0429EST

AOL News: Health Care Spending Climbed in 2000, Report Says  

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Proteins Needed To Ensure Accurate Chromosome Copies


Scientists have discovered that two proteins, previously known for helping to construct "silent" regions of chromosomes, also play an important but unforeseen role in building special structures that cells need to ensure accurate chromosome copying during cell division.The work was performed by researchers in Lawrence Berkeley National Laboratory's Life Sciences Division."When cells divide, they must make sure that both daughter cells receive exactly one copy of each chromosome," says Paul Kaufman, a staff scientist at Berkeley Lab and assistant adjunct professor of biochemistry and molecular biology at the University of California at Berkeley. "This process is known as chromosome segregation, and if it goes awry, cells can lose chromosomes or acquire more than one chromosome copy." In humans, lack of a chromosome can cause blood disorders including leukemia; an extra chromosome 21 causes Down Syndrome.As cell division begins, spindles form that will eventually pull the original chromosomes and their copies apart into two daughter cells. These spindles attach to constricted regions of chromosomes called centromeres: complexes of proteins called kinetochores fasten the centromeres to the spindles.To elucidate this process, Kaufman and his graduate students, Judith Sharp and Alexa Franco, focused their research on Saccharomyces cerevisiae, the familiar single-celled organism used for centuries to ferment beer and wine and to cause bread dough to rise. "We use yeast as a model system in which to investigate the fundamental building blocks of chromosomes," Kaufman says. "The structures we're studying are evolutionarily conserved and are much the same in many organisms, including humans."In particular, the researchers looked at two kinds of proteins known to be important for depositing proteins onto chromosomes. One, CAF-I (for Chromatin Assembly Factor I), puts together nucleosomes, the fundamental building blocks of chromosomes. Nucleosomes consist of DNA wrapped around groups of structural proteins called histones.Kaufman and his coworkers had previously demonstrated that CAF-I and another set of proteins, called Hir (for histone regulatory), are important for the formation of so-called "silenced" regions of chromosomes, where large stretches of DNA are enveloped in protein structures that repress gene expression. Silencing is vital to chromosome stability and accurate segregation. In higher organisms, loss of silencing can lead to cancer; even in yeast it can lead to developmental abnormalities and premature aging."We knew that CAF-I could assemble nucleosomes in a test tube, but it wasn't until we applied genetic tools that we discovered how much more there was to the picture," Kaufman says. "This is the advantage of working with yeast. It's easy to get rid of a specific gene and find out what happens when the protein it codes for is missing."When the researchers removed the genes that code for both CAF-I and Hir proteins, the growth rate of the yeast slowed markedly. Moreover, yeast lacking these genes lost chromosomes or gained extra ones hundreds of times more often than ordinary wild yeast. Yeast that lacked only one of the two genes was not similarly affected, however.The delay in cell division that occurred when both genes were missing seemed due to the activation of something called the "spindle assembly checkpoint," a mechanism that monitors the proper attachment of chromosomes to spindles before separation begins. This clue pointed to the involvement of kinetochores.Kaufman and his colleagues performed a series of tests indicating that both CAF-I and Hir proteins are highly localized on centromeres and therefore act directly to affect structures at these locations. Their functions seem to overlap; thus they can partially substitute for each other if one is missing. But when both are missing, defects in centromere structures occur."This the first demonstration that proteins that control histone deposition contribute to the formation of functional kinetochores," Kaufman says. "Kinetochores are essential to proper chromosome segregation during the cell division process."The Berkeley Lab is a U.S. Department of Energy national laboratory located in Berkeley, California. It conducts unclassified scientific research and is managed by the University of California. - By Paul Preuss(Reference: "Chromatin Assembly Factor I and Hir proteins contribute to building functional kinetochores in S. cerevisiae," by Judith A. Sharp, Alexa A. Franco, Mary Ann Osley, and Paul D. Kaufman, appears in the 1 January 2002 edition of Genes & Development. As of today, the text is accessible online at this URL.)

[Contact: Paul Preuss]

http://unisci.com/stories/20021/0108024.htm
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Immune system protein linked to ADHD


00:01 08 January 02
Emma Young

A common variation in a gene for an immune system protein increases a child's risk of developing Attention Deficit Hyperactivity Disorder (ADHD) by 30 per cent, say Israeli researchers.ADHD affects between four and 10 per cent of school age children and is characterised by inattention, hyperactivity and impulsivity. The causes are unknown. But stimulant drugs such as Ritalin, which boost levels of the neurotransmitter dopamine, have been shown to reduce symptoms in many patients. Other researchers have also found evidence linking ADHD to variations in certain genes exclusively involved in the dopamine system.Ronen Segman of the Hadassah-Hebrew University Medical Center in Jerusalem and colleagues studied 86 families with children diagnosed with ADHD. They found a significant association between a variation in the gene for the immune system protein interleukin-1 (IL-1) and ADHD. IL-1 is involved in the immune inflammatory response. But recent work has shown that it also has other roles in the body. IL-1 helps control the release of dopamine and another neurotransmitter called norepinephrine in several brain regions. It also helps promote the growth of dopamine-producing brain cells in the developing embryo."If replicated, these findings point to the importance of immune factors acting as neuromodulators," Segman told New Scientist. "This might form a basis for future new interventions for ADHD based on neuroimmune modulation."However, the causes of ADHD are complex, he adds. "A number of environmental factors such as maternal smoking, high levels of family problems and emotional stress during pregnancy have also been linked with the risk for ADHD."Journal reference: Molecular Psychiatry (vol 7, p 72)

http://www.newscientist.com/news/news.jsp?id=ns99991754
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Soon-to-be-ex-governor gives his pen a workout

Tuesday, January 8, 2002By BRUNO TEDESCHI
Trenton Bureau Chief

On his last full day in office Monday, acting Gov. Donald T. DiFrancesco signed 35 bills and vetoed or modified nine others, cutting some $130 million in proposed spending. DiFrancesco used a conditonal veto to block $128.3 million in spending for the repair of dams and dredging and cleanup of lakes and streams. A bill passed by the Legislature would have authorized $135 million in spending over five years. DiFrancesco's veto indicated he would accept $6.7 million for the 2002 fiscal year, which ends June 30.DiFrancesco said he supports the aims of the bill but is constrained by budget problems. He said it would be up to lawmakers in the next legislative session to address the problem.He used the conditional veto again on a bill that would have spent $350,000 on an Italian-American cultural commission. The veto indicated he would accept $250,000 there.DiFrancesco vetoed a bill that would have provided $180,000 to a business and industry consortium that makes grants to at-risk school districts.He said he supports the bill but wants to leave the decision to fund such a program to Governor-elect James E. McGreevey, who "has expressed interest in fostering corporate partnerships."McGreevey has called on DiFrancesco to reject any new spending because the state is facing a budget shortfall that the DiFrancesco administration admits could be as high as $1.4 billion. McGreevey believes the shortfall is closer to $1.9 billion.The Legislature passed more than 100 bills Monday. DiFrancesco can sign many more before he leaves office at noon today. On Monday, DiFrancesco said he would continue to cut spending out of bills that are passed."We've sent them messages about not wanting to sign some bills that are spending money, and we probably won't go along with the amounts of money in these bills," he said.Of the 35 bills DiFrancesco signed, only one spent additional money. The bill provides $1.5 million for researching and treating infantile autism.Bills vetoed conditionally must be approved by both houses of the Legislature before noon today to pass into law.
Copyright © 2002 North Jersey Media Group Inc.

http://www.bergen.com/news/disign200201085.htm
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When your 3-year-old isn’t talking

 

Professional testing is the best way to approach the problem


By Dr. Steven Parker
WEBMD

A child who has yet to start talking at the age of three may suffer from poor hearing or eyesight — or from something more serious, says Dr. Steven Parker, director of behavioral and developmental pediatrics at Boston Medical Center and an associate professor of pediatrics at the Boston University School of Medicine. Having the youngster evaluated by a professional is the first step to combating the problem.

Question: My 3-year-old has yet to start talking and I’m concerned. He seems very sensitive to sounds and tags in his shirts, and he won’t make eye contact with me. Occasionally, when he’s excited, he flaps his arms like he’s about to fly away. Other times, he seems to be in his own world and doesn’t react at all to his surroundings. My pediatrician is setting up a series of assessments for me: hearing, sight, etc. But I think it could be more. Can you help?
      

      Answer: It’s plain to see from your message that your child has a significant language delay. That, I think, you already know. Here’s the harder question: Is this solely a language problem or is this a language delay plus something else?
      Plus what? From your description, I’d have your guy evaluated for possible autistic spectrum disorder (also called pervasive developmental disorder, or PDD). There has been a marked increase in the diagnosis of this condition in the past decade. No one really knows whether it has become more prevalent or whether we are just getting better at recognizing and diagnosing it.
      Autistic spectrum disorder is suspected when a child has language difficulties plus many other atypical behaviors. Aside from poor language development, such children have poor communication skills in general. For example, they don’t point to what they want. Rather, they might grab a parent by the arm and take her to the refrigerator and just cry until you figure out what they might want. They never bring you a toy to show you. And they don’t seem to want to communicate much with others. If they do have language, they may use it in an unusual way. They might just repeat what someone else has just said (called “echolalia”) or only say memorized lines (like a commercial’s jingle).

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      Aside from the communication problems, the behavior of children with autistic spectrum disorder is often unusual. They may have a desire to keep the world the same.
      Lining up toys, rather than playing with them in an age-appropriate way, is common. They may get upset if their neatly ordered universe is disrupted. These children might be hypersensitive to a sensation, like sound, and may become agitated when things are too loud for their taste or when they are touched.
      
INTERACTIONS DIFFERENT
      Finally, their interactions with other people are different. They might make little or no eye contact with others and they may have little interest in playing with someone else. Many parents describe these children as “isolated in their own little world.” They may have unusual self-soothing movements, such as hand flapping or spinning around. Their emotions don’t always seem to coincide with what is happening around them.
      These are just some of the possible indications of autistic spectrum disorder. As the name implies, there is a wide variation in development and behavior for children with this problem. Some have only mild symptoms (which can be difficult to diagnose), while others have more severe symptoms.
      In any event, although no one knows what causes it (there are many theories), it’s pretty well accepted that early educational, speech and occupational therapies can improve long-term outcomes. So, yes, by all means get hearing and vision checked. But then I think you should also talk to your pediatrician about having your son evaluated by a professional with experience in diagnosing autistic spectrum disorder. Good luck!
      
     WebMD content is provided to MSNBC by the editorial staff of WebMD. The MSNBC editorial staff does not participate in the creation of WebMD content and is not responsible for WebMD content. Remember that editorial content is never a substitute for a visit to a health care professional.

http://www.msnbc.com/news/650119.asp?0si=-&cp1=1

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