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Vaccine 2002 Feb 22;20(11-12):1541-3 |
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Detection of measles vaccine in the throat of
a vaccinated child.
Morfin F, Beguin A, Lina B, Thouvenot D.
Laboratory of Virology, Hospices Civils de Lyon, Domaine Rockefeller, 8 avenue
Rockefeller, 69373 Cedex 08, Lyon, France
Measles vaccine is widely used, most often in association with mumps and
rubella vaccines. We report here the case of a child presenting with fever 8
days after vaccination with a measles-mumps-rubella vaccine. Measles virus was
isolated in a throat swab taken 4 days after fever onset. This virus was then
further genetically characterised as a vaccine-type virus. Fever occurring
subsequent to measles vaccination is related to the replication of the live
attenuated vaccine virus. In the case presented here, the vaccine virus was
isolated in the throat, showing that subcutaneous injection of an attenuated
measles strain can result in respiratory excretion of this virus.
PMID: 11858860 [PubMed - in process]
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